Nature Search

Randomness tests on the sequence of ascal segregation classes in Neurospora crassa

M R T Wickramaratne
B C Lamb
Research01 Dec 1976
Heredity

Volume: 37, P: 423-433
Growth Patterns in Neurospora: Genetic Control of a Cyclic Growth Pattern in Neurospora

D. R. STADLER
Research18 Jul 1959
Nature

Volume: 184, P: 170-171
Some data on segregation in Saccharomyces

Urs Leupold
Hélène Hottinguer
Research01 Aug 1954
Heredity

Volume: 8, P: 243-258
DDHD2 provides a flux of saturated fatty acids for neuronal energy and function

Saber et al. show that the lipase DDHD2 provides endogenous saturated fatty acids to support fatty acid oxidation and energy production, proteostasis and membrane trafficking balance.

Saber H. Saber
Nyakuoy Yak
Merja Joensuu
ResearchOpen Access30 Sept 2025
Nature Metabolism

P: 1-25
Small subunits can determine enzyme kinetics of tobacco Rubisco expressed in Escherichia coli

In plants, Rubisco is composed of 16 subunits and requires multiple chaperones to assemble. Features of individual tobacco Rubisco subunits that affect kinetic properties are investigated by coexpression with chaperones in Escherichia coli.

Myat T. Lin
William D. Stone
Maureen R. Hanson
Research14 Sept 2020
Nature Plants

Volume: 6, P: 1289-1299
Sodium Acetate Agar as a Sporulation Medium for Yeast

R. R. FOWELL
Research04 Oct 1952
Nature

Volume: 170, P: 578
Charcot–Marie–Tooth type 1A duplication appears to arise from recombination at repeat sequences flanking the 1.5 Mb monomer unit

Liu Pentao
Carol A. Wise
James R. Lupski
Research01 Dec 1992
Nature Genetics

Volume: 2, P: 292-300
Role of premeiotic replication in gene conversion

E. SILVA-LOPEZ
T. J. ZAMB
R. ROTH
Research01 Jan 1975
Nature

Volume: 253, P: 212-214
Observations on the polaron model for genetic recombination

D R Stadler
Research01 May 1963
Heredity

Volume: 18, P: 233-242
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Alterations in the tumour suppressor genes STK11 and/or KEAP1 can identify patients with advanced non-small-cell lung cancer who are likely to benefit from combinations of PD-(L)1 and CTLA4 immune checkpoint inhibitors added to chemotherapy.

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
ResearchOpen Access09 Oct 2024
Nature

Volume: 635, P: 462-471
Occurrence of Unusual Positive Coombs Reactions and M Factors in the Blood of a Mother and Her First Baby

R. JAKOBOWICZ
L. M. BRYCE
R. T. SIMMONS
Research28 Jan 1950
Nature

Volume: 165, P: 158-159
Vestibular function after spinal cord injury: preliminary results

K Ribarić-Jankes
R Čobeljić
B Pešić
Research27 Jan 2009
Spinal Cord

Volume: 47, P: 401-404
Structural Asymmetry in Cilia and Flagella

I. R. GIBBONS
Research17 Jun 1961
Nature

Volume: 190, P: 1128-1129
Permeability of Dormant Bacterial Spores

SAMUEL H. BLACK
R. E. MACDONALD
PHILIPP GERHARDT
Research12 Mar 1960
Nature

Volume: 185, P: 782-783
Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

Relocation of metabolic pathways to yeast mitochondria can increase production levels compared with expression of the same pathways in the cytoplasm.

José L Avalos
Gerald R Fink
Gregory Stephanopoulos
Research17 Feb 2013
Nature Biotechnology

Volume: 31, P: 335-341
Regulation of telomere length and function by a Myb-domain protein in fission yeast

Julia Promisel Cooper
Elaine R. Nimmo
Thomas R. Cech
Research20 Feb 1997
Nature

Volume: 385, P: 744-747
Study of some anomalies of copulation in Saccharomyces cerevisiae Hansen

Françoise Vezinhet
Monique Pellecuer
J Pasero
Research01 Aug 1975
Heredity

Volume: 35, P: 109-114
Maintenance of Heterozygosity in a Homothallic Species of the Neurospora tetrasperma Type

E. R. SANSOME
Research13 Apr 1946
Nature

Volume: 157, P: 484-485
PEX39 facilitates the peroxisomal import of PTS2-containing proteins

Chen et al. show that PEX39 cooperates with PEX7 in the peroxisomal import of proteins containing a PTS2 site and uncover an (R/K)PWE motif in PEX39 and PEX13 that binds to PEX7 and facilitates the import of PTS2-containing proteins.

Walter W. Chen
Tony A. Rodrigues
Bettina Warscheid
ResearchOpen Access30 Jul 2025
Nature Cell Biology

Volume: 27, P: 1256-1271
Increased sensitivity of lymphocyte Δ¹pyrroline-5-carboxylate reductase to inhibition by proline with transformation

DAVID VALLE
R. MICHAEL BLAESE
JAMES M. PHANG
Research01 Jan 1975
Nature

Volume: 253, P: 214-216
Use of High Molecular Weight Solutes in the Study of Isolated Intracellular Structures

JOHN H. McCLENDON
L. R. BLINKS
Research04 Oct 1952
Nature

Volume: 170, P: 577-578
Multispectral live-cell imaging with uncompromised spatiotemporal resolution

A tree-like arrangement of dichroic mirrors and multiple cameras coupled with an iterative spectral unmixing algorithm enables multispectral imaging of live cells in up to eight spectral channels with diffraction-limited spatial resolution and temporal resolution of 0.3 s for imaging a full cell volume.

Akaash Kumar
Kerrie E. McNally
James D. Manton
ResearchOpen Access08 Sept 2025
Nature Photonics

Volume: 19, P: 1146-1156
RECENT GENETICAL EXPERIMENTS WITH YEASTS

EVA R. SANSOME
Research12 Jan 1946
Nature

Volume: 157, P: 52-53
A fungal plant pathogen discovered in the Devonian Rhynie Chert

Here, the authors describe a pathogenic fungus from a 400-million-year-old fossil plant from the Devonian Rhynie Chert in Scotland. They use advanced imaging methods to determine that the fungus belongs to the sac fungi, the most diverse group of Fungi today.

Christine Strullu-Derrien
Tomasz Goral
David L. Hawksworth
ResearchOpen Access01 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness

Pluripotent cells are defined by their ability to self-renew: to proliferate indefinitely while maintaining their identity. Here, authors use genome-scale CRISPR knockout screens to untangle these two aspects of self-renewal.

Bess P. Rosen
Qing V. Li
Danwei Huangfu
ResearchOpen Access17 Oct 2024
Nature Communications

Volume: 15, P: 1-19
Comprehensive single-cell transcriptome lineages of a proto-vertebrate

Comprehensive single-cell transcriptomes in the proto-vertebrate Ciona intestinalis identified provisional gene networks for 41 different neural subtypes, providing insights into the swimming circuit of tadpoles and the evolution of the vertebrate telencephalon.

Chen Cao
Laurence A. Lemaire
Kai Chen
Research10 Jul 2019
Nature

Volume: 571, P: 349-354
Spinal cord and related injuries after attempted suicide: psychiatric diagnosis and long-term follow-up

R E Stanford
R Soden
T K F Taylor
Research06 Mar 2007
Spinal Cord

Volume: 45, P: 437-443
Multiplexed precision genome editing with trackable genomic barcodes in yeast

A method to introduce defined mutations into the yeast genome enables saturation mutagenesis of a gene and genome-scale introduction of genetic variants.

Kevin R Roy
Justin D Smith
Lars M Steinmetz
Research07 May 2018
Nature Biotechnology

Volume: 36, P: 512-520
Self-splicing RNA circularization facilitated by intact group I and II introns

RNA circularization is vital for circRNA therapeutics. Here, authors present two in vitro methods—PIET and CIRC—where CIRC employs intact self-splicing introns to generate circRNAs efficiently, and enables large circRNA generation, broadening the circRNA platform’s potential.

Yong Shen
Bohan Li
Wensheng Wei
ResearchOpen Access10 Aug 2025
Nature Communications

Volume: 16, P: 1-15
New Records of Eucrangonyx gracilis S. I. Smith and Gammarus tigrinus Sexton

R. BASSINDALE
Research13 Apr 1946
Nature

Volume: 157, P: 485
A rare PRIMER cell state in plant immunity

The development of a molecularly defined spatiotemporal atlas of pathogen-infected Arabidopsis thaliana leaves reveals specific cell states that have distinct roles in plant immunity.

Tatsuya Nobori
Alexander Monell
Joseph R. Ecker
ResearchOpen Access08 Jan 2025
Nature

Volume: 638, P: 197-205
Targeted gene correction of α₁-antitrypsin deficiency in induced pluripotent stem cells

Kosuke Yusa
S. Tamir Rashid
Ludovic Vallier
Research12 Oct 2011
Nature

Volume: 478, P: 391-394
Hypomyces Stage of Fusarium solani f. pisi

R. E. REICHLE
W. C. SNYDER
T. MATUO
Research08 Aug 1964
Nature

Volume: 203, P: 664-665
Boosting angiotensin-converting enzyme (ACE) in microglia protects against Alzheimer’s disease in 5xFAD mice

Gomez et al. show that boosting angiotensin-converting enzyme expression in microglia promotes phagocytic clearance of Aβ and endolysosomal trafficking, driven by spleen tyrosine kinase signaling in the 5xFAD transgenic model of Alzheimer’s disease.

Andrew R. Gomez
Hyae Ran Byun
Warren G. Tourtellotte
Research09 Jun 2025
Nature Aging

Volume: 5, P: 1280-1294
Substances Related to Vitamin A

I. M. HEILBRON
E. R. H. JONES
D. G. O'SULLIVAN
Research13 Apr 1946
Nature

Volume: 157, P: 485-486
Genome-scale analysis of interactions between genetic perturbations and natural variation

Here the authors investigate the interactions between genetic perturbations and segregating loci on a genome scale in yeast using barcoded CRISPRi. Strains’ responses to perturbations are shaped by perturbation-locus interactions that cannot be measured by examining perturbations or natural variation alone.

Joseph J. Hale
Takeshi Matsui
Ian M. Ehrenreich
ResearchOpen Access18 May 2024
Nature Communications

Volume: 15, P: 1-15
Projection-TAGs enable multiplex projection tracing and multi-modal profiling of projection neurons

Tools to simultaneously trace multiple neuronal projections and/or profile projection neurons for multi-modal investigations are lacking. Here authors introduce Projection-TAGs, a retrograde AAV platform to enable multiplexed spatial neuroanatomical studies, high-throughput multi-modal (transcriptional, and epigenetic) profiling of projection neurons using various commercial assays.

Lite Yang
Fang Liu
Vijay K. Samineni
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-18
NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis

Endodermal neurogenesis is an uncommon trait among animals. Here they identify a population of endoderm-specific neural progenitor cells in the cnidarian Nematostella vectensis that is characterized by the expression of the transcription factor prdm14d.

Quentin I. B. Lemaître
Natascha Bartsch
Fabian Rentzsch
ResearchOpen Access10 Aug 2023
Nature Communications

Volume: 14, P: 1-18
Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe

Elaine R. Nimmo
Alison L. Pidoux
Robin C. Allshire
Research01 Apr 1998
Nature

Volume: 392, P: 825-828
The yeast genome is globally accessible in living cells

The authors measure the accessibility of the yeast genome using DNA methylases. They show that the genome is globally accessible in living cells, except for centromeres and silenced loci, unlike in isolated nuclei, in which accessibility is strictly limited.

Hemant K. Prajapati
Peter R. Eriksson
David J. Clark
ResearchOpen Access25 Nov 2024
Nature Structural & Molecular Biology

Volume: 32, P: 247-256
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function

RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.

Alexander Sasse
Debashish Ray
Quaid Morris
ResearchOpen Access25 Jul 2025
Nature Biotechnology

P: 1-11
A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein

Li Muhua
Neil R. Adames
John A. Cooper
Research04 Jun 1998
Nature

Volume: 393, P: 487-491
Targeted accurate RNA consensus sequencing (tARC-seq) reveals mechanisms of replication error affecting SARS-CoV-2 divergence

Targeted accurate RNA consensus sequencing enables study of de novo errors caused by RNA-dependent RNA polymerases and provides deeper insights into how SARS-CoV-2 genetic diversity emerges.

Catherine C. Bradley
Chen Wang
Christophe Herman
Research22 Apr 2024
Nature Microbiology

Volume: 9, P: 1382-1392
Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation

Delivering MR1 ligand in the context of an MR1 monomer demonstrates transfer of this ligand onto cellular MR1. The stabilization of an inherently unstable ligand in the monomer has implications for antigen delivery and possibly vaccine design.

Corinna A. Kulicke
Gwendolyn M. Swarbrick
Melanie J. Harriff
ResearchOpen Access24 Feb 2024
Communications Biology

Volume: 7, P: 1-13
Wheat Pm4 resistance to powdery mildew is controlled by alternative splice variants encoding chimeric proteins

The wheat Pm4 gene conferring race-specific powdery mildew resistance is identified to encode a chimeric kinase-MCTP protein. Its two alternative splice variants interact to form an ER-associated complex and are both essential for resistance function.

Javier Sánchez-Martín
Victoria Widrig
Beat Keller
Research11 Mar 2021
Nature Plants

Volume: 7, P: 327-341
Genome organization around nuclear speckles drives mRNA splicing efficiency

Nuclear speckles are shown to have a functional role in mRNA splicing, whereby dynamic three-dimensional organization of DNA around these structures mediates splicing efficiency.

Prashant Bhat
Amy Chow
Mitchell Guttman
Research08 May 2024
Nature

Volume: 629, P: 1165-1173
Far-red fluorescent genetically encoded calcium ion indicators

Genetically-encoded indicators with more red-shifted excitation and emission wavelengths are advantageous for in vivo imaging. Here, Dalangin et al. report the engineering of far-red fluorescent Ca2+ indicators and demonstrate their utility for monitoring of all-optical cardiac pacing in embryonic zebrafish.

Rochelin Dalangin
Bill Z. Jia
Robert E. Campbell
ResearchOpen Access07 Apr 2025
Nature Communications

Volume: 16, P: 1-14
An activity-regulated transcriptional program directly drives synaptogenesis

Neuronal activity contributes to synapse formation and plasticity. Here the authors demonstrate that activity stimulates developmental programs to directly modulate synapse formation.

Callista Yee
Yutong Xiao
Kang Shen
ResearchOpen Access05 Aug 2024
Nature Neuroscience

Volume: 27, P: 1695-1707
Inactivation of Organo-Mercurial Fungicides in Groundwood Pulp made from Logs stored in Salt Water, and the Possible Role of Sulphur Compounds

B. H. BROWNING
P. RUSSELL
R. J. PEERLESS
Research09 May 1959
Nature

Volume: 183, P: 1346-1347
A transcriptional reporter of intracellular Ca²⁺ in Drosophila

The authors developed a transcriptional reporter of intracellular Ca²⁺ and used it to monitor activity in Drosophila sensory and neuromodulatory neurons. They demonstrate that this tool can be used to manipulate neurons basis of their activity and report variants that can be adapted to report activity across a wide range.

Xiaojing J Gao
Olena Riabinina
Liqun Luo
Research11 May 2015
Nature Neuroscience

Volume: 18, P: 917-925

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