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Showing 1–50 of 95 results

Advanced filters: Author: R Orlowski Clear advanced filters

Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy

LM Mir
LF Glass
R Heller
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 2336-2342
Electrochemotherapy on liver tumours in rabbits

LH Ramirez
S Orlowski
LM Mir
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 2104-2111
The role of the ubiquitin-proteasome pathway in apoptosis

Robert Z Orlowski
Reviews09 Apr 1999
Cell Death & Differentiation

Volume: 6, P: 303-313
Increased platinum accumulation in SA-1 tumour cells after in vivo electrochemotherapy with cisplatin

M Cemaz̆ar
D Miklavc̆ic̆
G Sers̆a
ResearchOpen Access26 Feb 1999
British Journal of Cancer

Volume: 79, P: 1386-1391
Enzymatic Dedifferentiation of Neoplastic Cells

M. THIERY
R. G. J. WILLIGHAGEN
Research30 Mar 1963
Nature

Volume: 197, P: 1312-1313
CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells

K-F Chen
C-Y Liu
A-L Cheng
Research23 Aug 2010
Oncogene

Volume: 29, P: 6257-6266
The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

Feroz R. Papa
Mark Hochstrasser
Research25 Dec 1993
Nature

Volume: 366, P: 313-319
Radiation effects and the leach rates of vitrified radioactive waste

W. G. Burns
A. E. Hughes
A. M. Stoneham
Research14 Jan 1982
Nature

Volume: 295, P: 130-132
1D thermoembolization model using CT imaging data for porcine liver

Rohan Amare
Danielle Stolley
Erik Cressman
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

The clinical benefit of anti-PD-1 antibody treatment is dependent on the extent to which exhausted CD8 T cells are reinvigorated in relation to the tumour burden of the patient.

Alexander C. Huang
Michael A. Postow
E. John Wherry
Research10 Apr 2017
Nature

Volume: 545, P: 60-65
Protein-altering germline mutations implicate novel genes related to lung cancer development

In lung cancer, relatively few germline mutations are known to impact risk. Here the authors looked at rare variants in 39,146 individuals and find novel germline mutations associated with risk, as well as implicating ATM and a new candidate gene for lung cancer risk.

Xuemei Ji
Semanti Mukherjee
Christopher I. Amos
ResearchOpen Access11 May 2020
Nature Communications

Volume: 11, P: 1-14
Is bortezomib superior to high-dose dexamethasone for the treatment of relapsed multiple myeloma?

Robert Z Orlowski
Comments & Opinion01 Jan 2006
Nature Clinical Practice Oncology

Volume: 3, P: 16-17
Characteristics and Functional Capacities of Human Cord Blood Granulocytes and Monocytes

L Marodi
P C J Leijh
R Van Furth
Research01 Nov 1984
Pediatric Research

Volume: 18, P: 1127-1131
The equilibrium and kinetic drug binding properties of the mouse P-gp1a and P-gp1b P-glycoproteins are similar

J C Taylor
D R Ferry
R Callaghan
ResearchOpen Access15 Oct 1999
British Journal of Cancer

Volume: 81, P: 783-789
Neurofibromatosis 2 tumour suppressor schwannomin interacts with βII-spectrin

Daniel R. Scoles
Duong P. Huynh
Stefan M. Pulst
Research01 Apr 1998
Nature Genetics

Volume: 18, P: 354-359
Giant retinal tear and retinal detachment with underlying retinitis pigmentosa and hearing loss

Robert Y Kim
Steven D Schwartz
Robert J Cooling
Research01 Nov 1996
Eye

Volume: 10, P: 697-700
Transcriptional repression by the HDAC4–RelB–p52 complex regulates multiple myeloma survival and growth

NF-κB has largely been known as a transcriptional activator. Here the authors show that a transcriptionally repressive NF-κB complex, HDAC4–RelB–p52, maintains repressive chromatin at proapoptotic genes Bim and BMF, and regulates multiple myeloma survival and growth in an ERK1 dependent manner.

Subrahmanya D. Vallabhapurapu
Sunil K. Noothi
Sivakumar Vallabhapurapu
Research12 Oct 2015
Nature Communications

Volume: 6, P: 1-15
Impact of clonal plasma cells in autografts on outcomes in high-risk multiple myeloma patients

Oren Pasvolsky
Denái R. Milton
Muzaffar H. Qazilbash
ResearchOpen Access03 May 2023
Blood Cancer Journal

Volume: 13, P: 1-7
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Christopher Amos and colleagues perform genome-wide association analysis for lung cancer using cohorts genotyped on the OncoArray and combing these with existing data. They identify 18 loci, 10 of which are new, finding heterogeneity across the different lung cancer subtypes, and explore candidate genes through eQTL analysis in lung tissue.

James D McKay
Rayjean J Hung
Christopher I Amos
Research12 Jun 2017
Nature Genetics

Volume: 49, P: 1126-1132
Characterization of Insulin-Like Growth Factor Binding Protein-3 in Chronic Renal Failure Serum

David R Powell
Francis Liu
Raymond L Hintz
Research01 Feb 1993
Pediatric Research

Volume: 33, P: 136-143
Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

Cell cycle kinetics of pre-leukemic stem cells (pre-LSCs) may be an important determinant of clonal evolution and therapeutic resistance. Here, the AUs use a transgenic T-ALL mouse model that allows non-dividing cells to be tracked and identify a subset of non-dividing pre-LSCs maintained by p21.

Cedric S. Tremblay
Jesslyn Saw
David J. Curtis
ResearchOpen Access30 Aug 2018
Nature Communications

Volume: 9, P: 1-13
Sensors and regulators of intracellular pH

The pH of individual cellular compartments is independently regulated and highly variable. Molecules that sense the proton concentration and dynamically transport acid and base equivalents stringently regulate pH to ensure that it is maintained at optimal levels for organellar function.

Joseph R. Casey
Sergio Grinstein
John Orlowski
Reviews09 Dec 2009
Nature Reviews Molecular Cell Biology

Volume: 11, P: 50-61
Optimal infused CD34⁺ cell dose in multiple myeloma patients undergoing upfront autologous hematopoietic stem cell transplantation

Oren Pasvolsky
Curtis Marcoux
Muzaffar H. Qazilbash
ResearchOpen Access31 Oct 2024
Blood Cancer Journal

Volume: 14, P: 1-8
A phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma

J Cavenagh
H Oakervee
K Yong
ResearchOpen Access05 Sept 2017
British Journal of Cancer

Volume: 117, P: 1295-1302
Control of oncogenesis and cancer therapy resistance

R Perona
I Sánchez-Pérez
ReviewsOpen Access03 Feb 2004
British Journal of Cancer

Volume: 90, P: 573-577
Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells

M Amit-Vazina
S Shishodia
Z Estrov
ResearchOpen Access21 Jun 2005
British Journal of Cancer

Volume: 93, P: 70-80
International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation

A Palumbo
O Sezer
S Lonial
Reviews04 Jun 2009
Leukemia

Volume: 23, P: 1716-1730
Multiple myeloma patients with a long remission after autologous hematopoietic stem cell transplantation

Oren Pasvolsky
Zhongya Wang
Muzaffar H. Qazilbash
ResearchOpen Access17 May 2024
Blood Cancer Journal

Volume: 14, P: 1-7
Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion

K Viola
S Kopf
M Grusch
ResearchOpen Access23 Oct 2012
British Journal of Cancer

Volume: 108, P: 564-569
Diagnostic value of protein induced by vitamin K absence (PIVKAII) and hepatoma-specific band of serum gamma-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to α-fetoprotein

R Cui
J He
X Chen
ResearchOpen Access10 Jun 2003
British Journal of Cancer

Volume: 88, P: 1878-1882
Outcomes of patients with multiple myeloma and 1q gain/amplification receiving autologous hematopoietic stem cell transplant: the MD Anderson cancer center experience

Oren Pasvolsky
Sassine Ghanem
Muzaffar H. Qazilbash
ResearchOpen Access10 Jan 2024
Blood Cancer Journal

Volume: 14, P: 1-8
Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia

Cedric S. Tremblay
Jesslyn Saw
David J. Curtis
ResearchOpen Access23 Jan 2025
Leukemia

Volume: 39, P: 577-589
Primary therapy with single agent bortezomib as induction, maintenance and re-induction in patients with high-risk myeloma: results of the ECOG E2A02 trial

A Dispenzieri
S Jacobus
P R Greipp
Research10 Jun 2010
Leukemia

Volume: 24, P: 1406-1411
Radionecrosis and cellular changes in small volume stereotactic brain radiosurgery in a porcine model

Hamed Zaer
Andreas Nørgaard Glud
Dariusz Orlowski
ResearchOpen Access01 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
The use of novel agents in the treatment of relapsed and refractory multiple myeloma

J P Laubach
A Mahindra
P G Richardson
Reviews10 Sept 2009
Leukemia

Volume: 23, P: 2222-2232
Phase I clinical trial with IL-2-transfected xenogeneic cells administered in subcutaneous metastatic tumours: clinical and immunological findings

E Tartour
M Mehtali
T Dorval
ResearchOpen Access14 Nov 2000
British Journal of Cancer

Volume: 83, P: 1454-1461
Transdermal Delivery of Heparin by Skin Electroporation

Mark R. Prausnitz
Elazer R. Edelman
James C. Weaver
Research01 Nov 1995
Bio/Technology

Volume: 13, P: 1205-1209
KRD vs. VRD as induction before autologous hematopoietic progenitor cell transplantation for high-risk multiple myeloma

Mahmoud R. Gaballa
Junsheng Ma
Muzaffar H. Qazilbash
Research06 May 2022
Bone Marrow Transplantation

Volume: 57, P: 1142-1149
Daratumumab-based quadruplet therapy for transplant-eligible newly diagnosed multiple myeloma with high cytogenetic risk

Natalie S. Callander
Rebecca Silbermann
Peter M. Voorhees
ResearchOpen Access22 Apr 2024
Blood Cancer Journal

Volume: 14, P: 1-8
Sensitization of tumour cells to lysis by virus-specific CTL using antibody-targeted MHC class I/peptide complexes

G S Ogg
P R Dunbar
P Savage
ResearchOpen Access03 Feb 2000
British Journal of Cancer

Volume: 82, P: 1058-1062
Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma

C S Chim
R Pang
R Liang
Research20 Sept 2007
Leukemia

Volume: 21, P: 2527-2536
Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)

A Arlt
I Bauer
H Schäfer
Research07 Sept 2009
Oncogene

Volume: 28, P: 3983-3996
Modified high-dose melphalan and autologous SCT for AL amyloidosis or high-risk myeloma: analysis of SWOG trial S0115

V Sanchorawala
A Hoering
B Barlogie
Research15 Jul 2013
Bone Marrow Transplantation

Volume: 48, P: 1537-1542
Siltuximab (CNTO 328) with lenalidomide, bortezomib and dexamethasone in newly-diagnosed, previously untreated multiple myeloma: an open-label phase I trial

J J Shah
L Feng
R Z Orlowski
ResearchOpen Access12 Feb 2016
Blood Cancer Journal

Volume: 6, P: e396
Cysteine proteinase cathepsin H in tumours and sera of lung cancer patients: relation to prognosis and cigarette smoking

A Schweiger
A Staib
J Kos
ResearchOpen Access20 Jan 2000
British Journal of Cancer

Volume: 82, P: 782-788
Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma

S Kikuchi
R Suzuki
K C Anderson
Research24 Mar 2015
Leukemia

Volume: 29, P: 1918-1927
Auto-SCT improves survival in systemic light chain amyloidosis: a retrospective analysis with 14-year follow-up

S Parmar
P Kongtim
M H Qazilbash
Research02 Jun 2014
Bone Marrow Transplantation

Volume: 49, P: 1036-1041
High-dose therapy with auto-SCT is feasible in high-risk cardiac amyloidosis

P Kongtim
M H Qazilbash
S Parmar
Research02 Mar 2015
Bone Marrow Transplantation

Volume: 50, P: 668-672
Prevention and management of adverse events of Novel agents in multiple myeloma: A consensus of the european myeloma network

H Ludwig
M Delforge
P Sonneveld
ReviewsOpen Access18 Dec 2017
Leukemia

P: 1-46
Increased expression of the major heat shock protein Hsp72 in human prostate carcinoma cells is dispensable for their viability but confers resistance to a variety of anticancer agents

Vladimir L Gabai
Karine R Budagova
Michael Y Sherman
Research21 Feb 2005
Oncogene

Volume: 24, P: 3328-3338

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