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Quantum emitters respond to weak near-field coupling with topological photonic waveguides, revealing polarization and spectral reshaping.

Group-IV color centers in diamond show promise for spin-photon interfaces, but precise positioning and activation are challenging. Here the authors combine site-controlled ion implantation with laser annealing and in-situ photoluminescence monitoring to create and tune individual tin vacancy centers in diamond.

Due to entrainment of mantle and crustal fragments, orangeites provide information about the deep Earth; however, the nature of the source of orangeites remains uncertain. Here, the authors suggest that mica-amphibole-rutile-ilmenite-diopside (MARID) enriched mantle produces the orangeite magmas.

This article reports finding of a highly oxidised mineral in diamond inclusion derived from mantle transition zone or lower mantle, very reduced areas on our planet. Such oxidised material is likely linked to subduction of carbonates into this region.

Understanding the molecular basis of leukaemia predisposition is essential for intervention. The authors here investigate germline genetic leukaemia predisposition by studying Shwachman-Diamond syndrome and report compensatory inactivating mutations in EIF6 and transforming biallelic TP53 alterations.

Phaeocystales are ecologically significant nanoplankton whose evolutionary history and functional diversity remain incompletely characterized. Here, the authors integrate genomic and transcriptomic data to reveal their lineage diversification, metabolic plasticity, and adaptation to polar and temperate regimes.

The functional organization of the posterior parietal cortex (PPC) for guiding eye movements has remained unknown. Here, the authors use functional ultrasound neuroimaging to reveal small, tuned clusters in PPC that reliably encode where we look over months to years.

Drugs that rescue function of episodic ataxia 1 (EA1) mutant potassium channels are lacking. Here, Manville et al identify and describe the molecular basis for Native American botanical ataxia remedies that directly rescue EA1 mutant channels.

This Primer provides a comprehensive road map into the experimental design, theory, data collection and interpretation of time-domain thermoreflectance (TDTR) experiments and variants for measuring the thermal properties of materials. The applications of TDTR are discussed, along with its inherent limitations, and future research directions for nanoscale thermal property measurements are presented.

NSF hydrolyzes ATP to disassemble SNARE complexes. Here, the authors find NSF colocalizes with syntaxin nanodomains, reveal disassembly of syntaxin oligomers and other pre-fusion cis-SNARE complexes by NSF, and show how sequential hydrolysis drives disassembly.

Photon collection from quantum emitters is difficult, and their scale requires the use of free-space optical measurement setups which prevent packaging of quantum devices. Here, the authors design and fabricate a metasurface that acts as an immersion lens to collect and collimate the emission of an individual emitter.

Enhanced aerobic oxidation of methane in the Arctic Ocean intensified carbon dioxide emissions during the Palaeocene–Eocene Thermal Maximum, potentially extending the event, according to biomarker records from an Arctic sediment core.

The validation of inhibitors targeting PurF, a novel drug target for tuberculosis drug discovery, is described.

The time at which plate tectonics were initiated on Earth is unclear. Geochemical analysis of diamonds suggests that recycled oxidized material could have been introduced to the mantle via subduction zones more than 3 billion years ago.

Arabzade, Shirnekhi, Varadharajan, Ippagunta and colleagues show that the zinc finger translocation-associated (ZFTA) fusion oncoproteins gain intrinsically disordered regions, inducing nuclear condensate formation and oncogenic activation.

3D visualisation of nano-scale crystals using X-ray ptychography shows that the aggregation of nanolites can increase magma viscosity, increasing the potential of magma fragmentation and a highly explosive volcanic eruption

The spontaneous breaking of chiral symmetry in ferroelectric nematic systems has opened new avenues for exploring exotic textures in liquid crystalline ferromagnets. Authors reveal that the polar smectic phase coexisting with a chiral ferroelectric nematic is itself helical, exhibits pseudo-ferrielectric switching, and shows both first- and second-order helix formation, with pre-transitional helices emerging in the nematic phase.

The ankylosaurian dinosaur Spicomellus afer possessed a tail weapon and uniquely elaborate dermal armour.

Resonant laser excitation is used to control the charge states of colour centre clusters in diamond with sub-diffraction resolution. These states are long-lived and can be read out non-destructively with low energy consumption.

Controlling electron spin states with light is vital for quantum technologies but requires electronic excitations with net spin. Now a molecular diradical with two trityl radical groups coupled via a meta-linked fluorene bridge has been developed that features luminescent singlet and triplet excitons. The spins in the ground state can be written and read using photons, giving rise to broad magnetic and microwave modulation of the photoluminescence.

Diorganozinc reagents (ZnR₂, e.g. R = Et, Ph, C₆F₅) are widely used as Lewis acid catalysts or Lewis base reagents, however, descriptors for predicting the influence of the R substituent are scarce. Here, by using liquid-phase X-ray spectroscopy, the authors have identified the geometric structures of diorganozincs in weakly coordinating solvents and then established Zn-specific descriptors to quantify the properties of their underlying Lewis acidity/basicity.

Protein sequence and structural similarities in large databases are rapidly identified using machine learning.

Lightning Pose is an efficient pose estimation approach that requires few labeled training data owing to its semi-supervised learning strategy and ensembling.

Spin–photon interfaces provide a connection between quantum information stored in atomic or electronic spins and optical communications networks. A quantum photon emitter with long-lived, controllable coherent spin has now been demonstrated.

The sexually transmitted human parasite Trichomonas vaginalis belongs to a clade of host-switching trichomonads that parasitize mammals, birds, livestock, and pets. Here the authors describe a chromosome-scale genome for T. vaginalis and assemblies of other bird and mammal-infecting species, identifying gene functions implicated in the spillover of trichomonads from birds to humans.

Atomistic simulations have a broad range of applications from drug design to materials discovery. Machine learning interatomic potentials (MLIPs) have become an efficient alternative to computationally expensive ab initio simulations. Now a general reactive MLIP (called ANI-1xnr) has been developed and validated against a broad range of condensed-phase reactive systems.

Antiferromagnets offer the potential for higher speed and density than ferromagnetic materials for spintronic devices. Here, Reimers et al study the domain structure of CuMnAs, demonstrating the role of defects in stabilizing the location and orientation of antiferromagnetic domain walls.

Gas adsorption in porous materials offers an alternative technology for efficient hydrogen isotope separation. Here, the authors report high separation efficiency through isotopologue-induced structural dynamics in a readily scalable manganese-triazole metal-organic framework.

Charge transfer is facilitated in molecular systems through orbital coupling. Here the authors use core-hole-clock spectroscopy to show that electron transfer from an argon atom caged in a fullerene can be up to two orders of magnitude faster than for the isolated atom.

Greg Barsh and colleagues show that two loci for dark skin in mice result from mutations in Rps19 and Rps20, encoding the ribosomal proteins S19 and S20. They further show that the dark skin phenotype and other pleiotropic effects of these mutations, including reduced erythrocyte count and body size, are mediated through stabilization of p53.

New fern transcriptomes reveal repeated whole-genome duplications, unique gene families and distinct lignocellulosic evolution, providing a comprehensive database that underscores the ancient divergence and genetic uniqueness of ferns.

Recent studies have shown that energy transfer photoenzymes can be engineered to promote stereocontrolled [2 + 2] cycloadditions; however, existing systems rely on ultraviolet light and display limited photochemical efficiencies. A generation of thioxanthone-containing photoenzymes now harnesses visible light to drive challenging photochemical conversions with high efficiencies and selectivities.

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Local shear stress from an atomic force microscope tip can control the crystal directions in thin oxide films. This approach enables the manipulation of local magnetic anisotropy in ferromagnetic metals.

A climatic record from desert speleothems shows that the central Arabian interior experienced recurrent humid intervals over the past 8 million years, which likely facilitated mammalian dispersals between Africa and Eurasia.

Genome-wide analyses identify common variants associated with 11 distinct neuropathology endophenotypes, providing insights into the mechanisms underlying the genetic risk of Alzheimer’s disease and related dementias.