Nature Search

A Flash-Photolytic Investigation of Rhodopsin at Low Temperatures

K-H. GRELLMANN
ROBERT LIVINGSTON
DOUGLAS PRATT
Research31 Mar 1962
Nature

Volume: 193, P: 1258-1260
Stereospecificity of Certain Soluble and Particulate Preparations of Mitochondrial Reduced Nicotinamide-Adenine Dinucleotide Dehydrogenase From Beef Heart

LARS ERNSTER
HENRY D. HOBERMAN
GIANLUIGI SOTTOCASA
Research28 Aug 1965
Nature

Volume: 207, P: 940-941
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling

Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism underlying genetic risk for these disorders.

Nora I. Strom
Brad Verhulst
John M. Hettema
ResearchOpen Access03 Feb 2026
Nature Genetics

Volume: 58, P: 275-288
Physical and Enzymatic Studies on Poly d(I–C).Poly d(I–C), an Unusual Double-helical DNA

Y. MITSUI
R. LANGRIDGE
ROBERT D. WELLS
Research19 Dec 1970
Nature

Volume: 228, P: 1166-1169
Psychiatric Ward Behaviour and Geophysical Parameters

HOWARD FRIEDMAN
ROBERT O. BECKER
CHARLES H. BACHMAN
Research13 Mar 1965
Nature

Volume: 205, P: 1050-1052
Crystallization of Transfer Ribonucleic Acids from Unfractionated Mixtures

JACQUES R. FRESCO
RICHARD D. BLAKE
ROBERT LANGRIDGE
Research28 Dec 1968
Nature

Volume: 220, P: 1285-1287
High-resolution X-ray Diffraction by Single Crystals of Mixtures of Transfer Ribonucleic Acids

RICHARD D. BLAKE
JACQUES R. FRESCO
ROBERT LANGRIDGE
Research03 Jan 1970
Nature

Volume: 225, P: 32-35
Making cancer research more inclusive

Based on a virtual discussion during the American Association for Cancer Research (AACR) 2020 Annual Meeting, we asked several scientists actively working to improve representation of Black American populations in cancer research how they are addressing these issues.

John D. Carpten
Lola Fashoyin-Aje
Robert Winn
Reviews29 Jun 2021
Nature Reviews Cancer

Volume: 21, P: 613-618
The covalent and tertiary structure of bovine liver rhodanese

Jan H. Ploegman
Gé Drent
John Russell
Research11 May 1978
Nature

Volume: 273, P: 124-129
The peculiar X-ray and radio star AS431

Jean-Pierre Caillault
Gary A. Chanan
Robert H. Becker
Research31 Jan 1985
Nature

Volume: 313, P: 376-378
Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells

Reduced fitness of the tumor microenvironment is mediated by a long non-coding RNA expressed in tumors.

Esha Madan
António M. Palma
Rajan Gogna
Research09 Dec 2024
Nature Biotechnology

Volume: 43, P: 1833-1847
Global fire at the Cretaceous– Tertiary boundary

Wendy S. Wolbach
Iain Gilmour
Robert R. Brooks
Research01 Aug 1988
Nature

Volume: 334, P: 665-669
Multi-scale and multi-context interpretable mapping of cell states across heterogeneous spatial samples

The alignment of heterogeneous spatial samples has become a growing challenge. Here, authors present a multi-scale, multi-context, and interpretable mapping strategy to map cells across space, time, and disease.

Patrick C. N. Martin
Wenqi Wang
Kyoung Jae Won
ResearchOpen Access21 Aug 2025
Nature Communications

Volume: 16, P: 1-17
Hepatitis-B vaccine: Tempers fray as production nears

Robert Walgate
News28 Jul 1983
Nature

Volume: 304, P: 297
Doubly charged Negative Ions of Oxygen, Fluorine, Chlorine and Bromine

WAYNE K. STUCKEY
ROBERT W. KISER
Research27 Aug 1966
Nature

Volume: 211, P: 963-964
Terpene Formation in Pine from Mevalonic Acid

ROBERT G. STANLEY
Research13 Sept 1958
Nature

Volume: 182, P: 738-739
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Genome-wide association meta-analyses of attention-deficit/hyperactivity disorder symptom measures and clinical diagnoses identify new risk loci, highlight putative effector genes and yield improved polygenic risk scores.

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Research17 Sept 2025
Nature Genetics

Volume: 57, P: 2427-2435
New method for the measurement of osmium isotopes applied to a New Zealand Cretaceous/Tertiary boundary shale

Frederick E. Lichte
Shane M. Wilson
Douglas E. Ryan
Research28 Aug 1986
Nature

Volume: 322, P: 816-817
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Aspartate aminotransferase-like immunoreactivity as a marker for aspartate/glutamate in guinea pig photoreceptors

Richard A. Altschuler
Judith L. Mosinger
Robert J. Wenthold
Research12 Aug 1982
Nature

Volume: 298, P: 657-659
UK nuclear power: At last, a plan

Robert Walgate
News28 Jan 1982
Nature

Volume: 295, P: 272-273
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Here, the authors perform large trans-ancestry fine-mapping analyses identifying large numbers of association signals and putative target genes for colorectal cancer risk, advancing our understanding of the genetic and biological basis of this cancer.

Zhishan Chen
Xingyi Guo
Wei Zheng
ResearchOpen Access26 Apr 2024
Nature Communications

Volume: 15, P: 1-17
Identification of the herpes simplex virus DNA polymerase gene

DOROTHY J. M. PURIFOY
ROBERT B. LEWIS
KENNETH L. POWELL
Research01 Oct 1977
Nature

Volume: 269, P: 621-623
Sequence of a novel simian immunodeficiency virus from a wild-caught African mandrill

Hajime Tsujimoto
Akira Hasegawa
Masanori Hayami
Research12 Oct 1989
Nature

Volume: 341, P: 539-541
The unusual supernova SN1993J in the galaxy M81

Brian P. Schmidt
Robert P. Kirshner
Alejandra A. E. Milone
Research12 Aug 1993
Nature

Volume: 364, P: 600-602
Male Skin Isograft Acceptance in Female Mice of the C57BL/1 Strain after Repeated Injections of Disrupted Spleen Cells

CARLOS MARTINEZ
MICHAEL BLAESE
ROBERT A. GOOD
Research29 Jun 1963
Nature

Volume: 198, P: 1319-1321
Grooming, alliances and reciprocal altruism in vervet monkeys

Robert M. Seyfarth
Dorothy L. Cheney
Research05 Apr 1984
Nature

Volume: 308, P: 541-543
PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

Neuroinflammation has been proposed to accompany the peripheral inflammation observed in PTSD. Here, authors find lower in vivo and postmortem levels of neuroimmune marker TSPO (translocator protein) in PTSD, in association with greater PTSD severity and higher plasma CRP.

Shivani Bhatt
Ansel T. Hillmer
Kelly P. Cosgrove
ResearchOpen Access12 May 2020
Nature Communications

Volume: 11, P: 1-11
Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

Phillip W. Berman
Timothy J. Gregory
Jorg W. Eichberg
Research14 Jun 1990
Nature

Volume: 345, P: 622-625
Parental origin of mutations of the retinoblastoma gene

Thaddeus P. Dryja
Shizuo Mukai
David W. Yandell
Research15 Jun 1989
Nature

Volume: 339, P: 556-558
Responses of cells in monkey visual cortex during perceptual filling-in of an artificial scotoma

Peter De Weerd
Ricardo Gattass
Leslie G. Ungerleider
Research26 Oct 1995
Nature

Volume: 377, P: 731-734
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

A multi-ancestry genome-wide association study meta-analysis, combined with transcriptome- and methylome-wide association analyses, identifies risk loci associated with colorectal cancer. Credible effector genes and their target tissues are also highlighted, showing that over a third probably act outside the colonic mucosa.

Ceres Fernandez-Rozadilla
Maria Timofeeva
Ulrike Peters
Research20 Dec 2022
Nature Genetics

Volume: 55, P: 89-99
Pembrolizumab plus chemotherapy in advanced or recurrent endometrial cancer: overall survival and exploratory analyses of the NRG GY018 phase 3 randomized trial

Secondary and exploratory analyses of the phase 3 NRG GY018 trial show that, in patients with advanced or recurrent endometrial cancer, first-line treatment with pembrolizumab together with paclitaxel and carboplatin leads to prolonged progression-free survival, according to blinded independent central review.

Ramez N. Eskander
Michael W. Sill
Carol Aghajanian
Research05 Mar 2025
Nature Medicine

Volume: 31, P: 1539-1546
Harvesting a crop of gold in plants

Christopher W. N. Anderson
Robert R. Brooks
Robyn Simcock
Research08 Oct 1998
Nature

Volume: 395, P: 553-554
Characterization and Uses of Human Diploid Cell Strains

LEONARD HAYFLICK
FRANK T. PERKINS
ROBERT E. STEVENSON
News21 Dec 1963
Nature

Volume: 200, P: 1161
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

A systematic review of evidence, across the key pillars of prevention, diagnosis, treatment and prognosis, outlines milestones that need to be met to enable the broad clinical implementation of precision medicine in diabetes care.

Deirdre K. Tobias
Jordi Merino
Paul W. Franks
Reviews05 Oct 2023
Nature Medicine

Volume: 29, P: 2438-2457
Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide and genetic susceptibility to the disease is poorly understood. Here, the authors combine data from Japanese, African American and European samples and identify a common variant in VTI1Athat increases CRC risk across all populations.

Hansong Wang
Terrilea Burnett
Loïc Le Marchand
Research08 Aug 2014
Nature Communications

Volume: 5, P: 1-7
Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review

Young, McInnes, Massey et al. systematically review published studies evaluating features associated with heterogenous treatment effects for SGLT2-inhibitor and GLP1-receptor agonist therapies in people with type 2 diabetes. They find limited current evidence on treatment effect heterogeneity, for glycaemic, cardiovascular and renal outcomes.

Katherine G. Young
Eram Haider McInnes
Paul W. Franks
ResearchOpen Access05 Oct 2023
Communications Medicine

Volume: 3, P: 1-20
Human influence on climate in the 2014 southern England winter floods and their impacts

An ensemble of climate model simulations, as well as hydrological modelling and flood risk mapping, are used to show the role of anthropogenic warming on the extreme rainfall that caused the 2013/14 floods in southern England.

Nathalie Schaller
Alison L. Kay
Myles R. Allen
Research01 Feb 2016
Nature Climate Change

Volume: 6, P: 627-634
Economic damages from Hurricane Sandy attributable to sea level rise caused by anthropogenic climate change

Sea level rise amplifies coastal storm impacts, but the role of anthropogenic climate change is poorly resolved. Here the authors reassess Hurricane Sandy, using a dynamic flood model to show that anthropogenic sea level rise added a central estimate of $8 billion in damages.

Benjamin H. Strauss
Philip M. Orton
Sergey Vinogradov
ResearchOpen Access18 May 2021
Nature Communications

Volume: 12, P: 1-9
Nutritional deficiencies in German middle-class male alcohol consumers: relation to dietary intake and severity of liver disease

I Bergheim
A Parlesak
C Bode
Research10 Mar 2003
European Journal of Clinical Nutrition

Volume: 57, P: 431-438
Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

Germline biallelic pathogenic MUTYH variants predispose patients to colorectal cancer (CRC); however, approaches to identify MUTYH variant carriers are lacking. Here, the authors evaluated mutational signatures that could distinguish MUTYH carriers in large CRC cohorts, and found MUTYH-associated somatic mutations.

Peter Georgeson
Tabitha A. Harrison
Daniel D. Buchanan
ResearchOpen Access06 Jun 2022
Nature Communications

Volume: 13, P: 1-12
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Directed conservation of the world’s reef sharks and rays

A survey of sharks and rays on coral reefs within 66 marine protected areas across 36 countries showcases that the conservation benefits of full MPA protection to sharks almost double when accompanied by effective fisheries management.

Jordan S. Goetze
Michael R. Heithaus
Demian D. Chapman
Research20 May 2024
Nature Ecology & Evolution

Volume: 8, P: 1118-1128
Global spatial risk assessment of sharks under the footprint of fisheries

A global dataset of the satellite-tracked movements of pelagic sharks and fishing fleets show that sharks—and, in particular, commercially important species—have limited spatial refuge from fishing effort.

Nuno Queiroz
Nicolas E. Humphries
David W. Sims
Research24 Jul 2019
Nature

Volume: 572, P: 461-466
Synthesizing evidence for the external cycling of NO_x in high- to low-NO_x atmospheres

External cycling regenerates nitrogen oxides from the NO_x oxidative reservoir, NO_z. Aircraft observations reveal NO_x external cycling compensates for NO_x aging, sustaining NO_x distribution and production of OH radicals far from NO_x emission sources

Chunxiang Ye
Xianliang Zhou
Shaojie Song
ResearchOpen Access02 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Dense sampling of bird diversity increases power of comparative genomics

A dataset of the genomes of 363 species from the Bird 10,000 Genomes Project shows increased power to detect shared and lineage-specific variation, demonstrating the importance of phylogenetically diverse taxon sampling in whole-genome sequencing.

Shaohong Feng
Josefin Stiller
Guojie Zhang
Research11 Nov 2020
Nature

Volume: 587, P: 252-257
Predicting the replicability of social and behavioural science claims in COVID-19 preprints

This study assessed COVID-19 social science preprints’ replicability using structured groups. Both beginners and more-experienced participants used a elicitation protocol to make better-than-chance predictions about the reliability of research claims under high uncertainty.

Alexandru Marcoci
David P. Wilkinson
Sander van der Linden
ResearchOpen Access20 Dec 2024
Nature Human Behaviour

Volume: 9, P: 287-304
Participant characteristics in the effectiveness of lifestyle interventions to optimize gestational weight gain: a systematic review and meta-analysis

Grieger, Takele, Vesco, et al. perform a systematic review and meta-analysis of gestational weight gain interventions. Findings indicate lifestyle interventions that reduce excessive gestational weight gain provide greater benefits for women with a normal BMI and higher HDL cholesterol levels at the initiation of interventions.

Jessica A. Grieger
Wubet Worku Takele
Siew Lim
ResearchOpen Access24 Oct 2025
Communications Medicine

Volume: 5, P: 1-13
Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Amendments and Corrections29 Sept 2025
Nature Genetics

Volume: 57, P: 2604

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