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Showing 801–850 of 934 results

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Treatment failure patterns in early versus late introduction of CAR T-cell therapy in large B-cell lymphoma

Magdalena Corona
Andrew Ip
Roni Shouval
Research01 Feb 2025
Bone Marrow Transplantation

Volume: 60, P: 491-498
A machine learning approach to explore predictors of graft detachment following posterior lamellar keratoplasty: a nationwide registry study

M. B. Muijzer
C. M. W. Hoven
Robert P. L. Wisse
ResearchOpen Access21 Oct 2022
Scientific Reports

Volume: 12, P: 1-9
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment

Sonia Missiroli
Mariasole Perrone
Carlotta Giorgi
Research30 Nov 2022
Cell Death & Differentiation

Volume: 30, P: 429-441
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

Thomas W. Winkler
Humaira Rasheed
Iris M. Heid
ResearchOpen Access13 Jun 2022
Communications Biology

Volume: 5, P: 1-20
Precision Military Medicine: Conducting a multi-site clinical utility study of genomic and lifestyle risk factors in the United States Air Force

Susan K. Delaney
Ruth Brenner
Michael F. Christman
ReviewsOpen Access19 Jan 2017
npj Genomic Medicine

Volume: 2, P: 1-5
Dried plum diet protects from bone loss caused by ionizing radiation

A.-S. Schreurs
Y. Shirazi-Fard
R. K. Globus
ResearchOpen Access11 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

A multicenter comparison of DNA methylation assays identifies robust methods for translational research and clinical diagnostics.

Christoph Bock
Florian Halbritter
Kun Zhang
ResearchOpen Access27 Jun 2016
Nature Biotechnology

Volume: 34, P: 726-737
Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies

An epigenome-wide association study of dementia with Lewy bodies discovers differentially methylated probes, genomic regions and pathways associated with this disease.

Paolo Reho
Sara Saez-Atienzar
Sonja W. Scholz
ResearchOpen Access05 Jan 2024
Communications Biology

Volume: 7, P: 1-10
Vibrio cholerae and Salmonella Typhi culture-based wastewater or non-sewered sanitation surveillance in a resource-limited region

Petros Chigwechokha
Ruth Lusungu Nyirenda
Rochelle H. Holm
Research04 Jan 2024
Journal of Exposure Science & Environmental Epidemiology

Volume: 34, P: 432-439
Epigenetic Achilles’ heel of AML

Mutations in genes encoding epigenetic modifiers are frequent in acute myelogenous leukemia (AML) and have been proposed to cause AML via activation of oncogenes and repression of tumor suppressors. Two studies now identify unexpected oncogenic mechanisms and therapeutic vulnerabilities in AML arising from mutations in genes encoding the epigenetic regulators DNMT3A and ASXL1.

Koki Ueda
Ulrich Steidl
News & Views25 May 2021
Nature Cancer

Volume: 2, P: 481-483
Desmoplasia in cervical cancer is associated with a more aggressive tumor phenotype

Benjamin Wolf
Laura Weydandt
Bahriye Aktas
ResearchOpen Access02 Nov 2023
Scientific Reports

Volume: 13, P: 1-9
Bladder management, severity of injury and period of latency: a descriptive study on 135 patients with spinal cord injury and bladder cancer

Ralf Böthig
Birgitt Kowald
Klaus Golka
Research17 Jun 2021
Spinal Cord

Volume: 59, P: 971-977
Effects of training and using an audio-tactile sensory substitution device on speech-in-noise understanding

K. Cieśla
T. Wolak
A. Amedi
ResearchOpen Access25 Feb 2022
Scientific Reports

Volume: 12, P: 1-16
Glucose and unstructured physical activity coupling during sleep and wake in young adults with type 1 diabetes

Stephanie Griggs
Eric Barbato
Ronald L. Hickman Jr.
ResearchOpen Access06 Apr 2022
Scientific Reports

Volume: 12, P: 1-8
Is it time to report carrier state for recessive disorders in every microarray analysis?—A pilot model based on hearing loss genes deletions

Idit Maya
Lina Basel-Salmon
Lena Sagi-Dain
Research22 Mar 2021
European Journal of Human Genetics

Volume: 29, P: 1292-1300
Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented individuals: topographical patterns across two independent cohorts

Raffaele Cacciaglia
Gemma Salvadó
Natalia Vilor-Tejedor
ResearchOpen Access02 Mar 2022
Molecular Psychiatry

Volume: 27, P: 2010-2018
Nerves in cancer

This Review discusses the role that nerves play in the initiation and progression of cancers, focusing on the evidence that tumours may reactivate nerve-mediated developmental and regenerative pathways to promote their own growth and survival.

Ali H. Zahalka
Paul S. Frenette
Reviews23 Jan 2020
Nature Reviews Cancer

Volume: 20, P: 143-157
Interview: Sandra White: 'Dentists need to get more political'

Dr Sandra White has been the National Lead for Dental Public Health at Public Health England (PHE) since 2014. Before taking on her current role, Sandra has had a varied and substantial career in dentistry working as a consultant in dental public health for many years, before which she worked in various roles in special care dentistry, general dental practice and oral surgery.

Ruth Doherty
Comments & Opinion09 Dec 2016
British Dental Journal

Volume: 221, P: 692-695
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

The UK Biobank Exome Sequencing Consortium aims to sequence all the exomes of approximately 500,000 UK Biobank participants. This Perspective describes the results from approximately 200,000 exomes and discusses the lessons learned from this UK Biobank–biopharmaceutical company collaboration.

Joseph D. Szustakowski
Suganthi Balasubramanian
Zhan Ye
Reviews28 Jun 2021
Nature Genetics

Volume: 53, P: 942-948
Functional MRI-based lie detection: scientific and societal challenges

The scientific and legal interest in functional MRI-based lie detection has grown rapidly in the past decade. In this Perspective, Farah and colleagues review the scientific state of the art of this approach to lie detection, discuss its legal status and consider broader ethical and societal implications.

Martha J. Farah
J. Benjamin Hutchinson
Anthony D. Wagner
Comments & Opinion20 Jan 2014
Nature Reviews Neuroscience

Volume: 15, P: 123-131
Persistent thinness and anorexia nervosa differ on a genomic level

Christopher Hübel
Mohamed Abdulkadir
Cynthia M. Bulik
ResearchOpen Access20 Jul 2023
European Journal of Human Genetics

Volume: 32, P: 117-124
Nemaline myopathy: reclassification of previously reported variants according to ACMG guidelines, and report of novel genetic variants

Alireza Haghighi
Zahra Alvandi
Robert J. Desnick
Research18 Jul 2023
European Journal of Human Genetics

Volume: 31, P: 1237-1250
Clinical exome sequencing efficacy and phenotypic expansions involving anomalous pulmonary venous return

Emily A. Huth
Xiaonan Zhao
Daryl A. Scott
Research07 Sept 2023
European Journal of Human Genetics

Volume: 31, P: 1430-1439
Good laboratory practice for clinical next-generation sequencing informatics pipelines

Amy S Gargis
Lisa Kalman
Ira M Lubin
Correspondence08 Jul 2015
Nature Biotechnology

Volume: 33, P: 689-693
The CHD4-related syndrome: a comprehensive investigation of the clinical spectrum, genotype–phenotype correlations, and molecular basis

Karin Weiss
Hayley P. Lazar
Katherine Lachlan
Research07 Aug 2019
Genetics in Medicine

Volume: 22, P: 389-397
Facetime vs. Screentime: Gaze Patterns to Live and Video Social Stimuli in Adolescents with ASD

R. B. Grossman
E. Zane
T. Mitchell
ResearchOpen Access02 Sept 2019
Scientific Reports

Volume: 9, P: 1-10
Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

Sheng-Yao Huang
Jung-Lung Hsu
Balebail Ashok Raj
ResearchOpen Access14 Sept 2018
Scientific Reports

Volume: 8, P: 1-11
Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Garam Lee
Kwangsik Nho
Kristin Fargher
ResearchOpen Access13 Feb 2019
Scientific Reports

Volume: 9, P: 1-12
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

The International Glaucoma Genetics Consortium reports a genome-wide association study meta-analysis of optic disc parameters relevant to primary open-angle glaucoma. They identify two novel variants in PPP1R36-PLEKHG3 and SERPINE3 by multi-trait analysis in European-ancestry cohorts that were replicated in independent Asian cohorts.

Pieter W. M. Bonnemaijer
Elisabeth M. van Leeuwen
Cornelia M. van Duijn
ResearchOpen Access27 Nov 2019
Communications Biology

Volume: 2, P: 1-12
First-line exome sequencing in Palestinian and Israeli Arabs with neurological disorders is efficient and facilitates disease gene discovery

Holger Hengel
Rebecca Buchert
Ludger Schöls
ResearchOpen Access25 Mar 2020
European Journal of Human Genetics

Volume: 28, P: 1034-1043
ERK Activity in Immature Leukemic Cells Drives Clonal Selection during Induction Therapy for Acute Myeloid Leukemia

Michal Hayun
Maria Zaatra
Yishai Ofran
ResearchOpen Access20 May 2020
Scientific Reports

Volume: 10, P: 1-12
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

Lisa Borghini
Eileen Png
Peter Schermann
ResearchOpen Access06 May 2019
Scientific Reports

Volume: 9, P: 1-15
Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours

Rebecca Kristeleit
Jeffry Evans
Juanita Lopez
ResearchOpen Access03 Aug 2020
British Journal of Cancer

Volume: 123, P: 1360-1369
Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium

Emily L. Dennis
Seth G. Disner
Rajendra A. Morey
Research19 Dec 2019
Molecular Psychiatry

Volume: 26, P: 4315-4330
The Coral Trait Database, a curated database of trait information for coral species from the global oceans

Joshua S. Madin
Kristen D. Anderson
Andrew H. Baird
ResearchOpen Access29 Mar 2016
Scientific Data

Volume: 3, P: 1-22
Oxygen saturation histogram classification system to evaluate response to doxapram treatment in preterm infants

Liron Borenstein-Levin
Jarinda A. Poppe
Sinno H. P. Simons
Research23 Jun 2022
Pediatric Research

Volume: 93, P: 932-937
Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia

Sarra L. Ryan
John F. Peden
Mark T. Ross
ResearchOpen Access19 Jan 2023
Leukemia

Volume: 37, P: 518-528
Cortical profiles of numerous psychiatric disorders and normal development share a common pattern

Zhipeng Cao
Renata B. Cupertino
Hugh Garavan
Research15 Nov 2022
Molecular Psychiatry

Volume: 28, P: 698-709
Identification of fusions with potential clinical significance in melanoma

Jakob M. T. Moran
Long P. Le
Mai P. Hoang
Research23 Jul 2022
Modern Pathology

Volume: 35, P: 1837-1847
Collagen Type 1 Accelerates Healing of Ruptured Fetal Membranes

Haruta Mogami
Annavarapu Hari Kishore
R. Ann Word
ResearchOpen Access12 Jan 2018
Scientific Reports

Volume: 8, P: 1-9
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Yuetiva Deming
Jian Xia
Carlos Cruchaga
ResearchOpen Access04 Jan 2016
Scientific Reports

Volume: 6, P: 1-17
Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns

Jong-Yun Park
Han Kyu Na
Balebail Ashok Raj
ResearchOpen Access09 Mar 2017
Scientific Reports

Volume: 7, P: 1-14
Phenol-soluble modulin α4 mediates Staphylococcus aureus-associated vascular leakage by stimulating heparin-binding protein release from neutrophils

Lin li
Yaya Pian
Yongqiang Jiang
ResearchOpen Access07 Jul 2016
Scientific Reports

Volume: 6, P: 1-12
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features

Asha Singanamalli
Haibo Wang
Kristin Fargher
ResearchOpen Access15 Aug 2017
Scientific Reports

Volume: 7, P: 1-14
Clinicohematologic and molecular response of essential thrombocythemia patients treated with pegylated interferon-α: a multi-center study of the German Study Group-Myeloproliferative Neoplasms (GSG-MPN)

Frank Stegelmann
Lino L. Teichmann
Steffen Koschmieder
ResearchOpen Access24 Feb 2023
Leukemia

Volume: 37, P: 924-928
Healing of Preterm Ruptured Fetal Membranes

Haruta Mogami
Annavarapu Hari Kishore
R. Ann Word
ResearchOpen Access13 Oct 2017
Scientific Reports

Volume: 7, P: 1-15
Different formulas, different thresholds and different performance—the prediction of macrosomia by ultrasound

A Aviram
Y Yogev
R Gabbay-Benziv
Research14 Sept 2017
Journal of Perinatology

Volume: 37, P: 1285-1291
Precision prognostics for cardiovascular disease in Type 2 diabetes: a systematic review and meta-analysis

Ahmad, Lim, Morieri, Tam et al perform a systematic review and meta-analysis of biomarkers, genetic markers, and risk scores for prediction of cardiovascular outcomes in Type 2 diabetes. A few prognostic markers are identified that provide incremental predictive utility beyond established cardiovascular risk factors.

Abrar Ahmad
Lee-Ling Lim
Nestoras Mathioudakis
ResearchOpen Access22 Jan 2024
Communications Medicine

Volume: 4, P: 1-28
Childhood overeating is associated with adverse cardiometabolic and inflammatory profiles in adolescence

Christopher Hübel
Moritz Herle
Nadia Micali
ResearchOpen Access14 Jun 2021
Scientific Reports

Volume: 11, P: 1-15
Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study

Rajiv V. Dave
Baek Kim
Zaid Al-Ishaq
ResearchOpen Access25 Mar 2021
British Journal of Cancer

Volume: 124, P: 1785-1794

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