Nature Search

Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
New therizinosaurid dinosaur from the marine Osoushinai Formation (Upper Cretaceous, Japan) provides insight for function and evolution of therizinosaur claws

Yoshitsugu Kobayashi
Ryuji Takasaki
Yoshinori Hikida
ResearchOpen Access03 May 2022
Scientific Reports

Volume: 12, P: 1-12
Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509

Masato Iwatsuki
Ryuji Uchida
Satoshi Ōmura
Research01 Apr 2008
The Journal of Antibiotics

Volume: 61, P: 230-236
A case of Baraitser–Winter cerebrofrontofacial syndrome diagnosed by whole-exome sequencing

Kenichi Suga
Hiroki Sato
Maki Urushihara
ResearchOpen Access03 Sept 2025
Human Genome Variation

Volume: 12, P: 1-3
Electrophoretic variants of blood proteins in Japanese V. Ceruloplasmin

Mikio Fujita
Chiyoko Satoh
Kazuaki Goriki
Research01 Jun 1985
Japanese journal of human genetics

Volume: 30, P: 43-50
Structure Elucidation of Fungal Sespendole, an Inhibitor of Lipid Droplet Synthesis in Macrophages

Ryuji Uchida
Yong-Pil Kim
Satoshi Ōmura
Research01 Jun 2006
The Journal of Antibiotics

Volume: 59, P: 338-344
Yaequinolones, New Insecticidal Antibiotics Produced by Penicillium sp. FKI-2140

Ryuji Uchida
Rie Imasato
Satoshi Ōmura
Research01 Oct 2006
The Journal of Antibiotics

Volume: 59, P: 652-658
New Insecticidal Antibiotics, Hydroxyfungerins A and B, Produced by Metarhizium sp. FKI-1079

Ryuji Uchida
Rie Imasato
Satoshi Ōmura
Research01 Dec 2005
The Journal of Antibiotics

Volume: 58, P: 804-809
Electrophoretic variants of blood proteins in Japanese VI. Transferrin

Mikio Fujita
Chiyoko Satoh
Todor Krasteff
Research01 Sept 1985
Japanese journal of human genetics

Volume: 30, P: 191-200
Superconductivity in a van der Waals layered quasicrystal

Recent theoretical work has shown that quasicrystal (QC) superconductors should exhibit unconventional behaviors, such as vortex pinning without impurities and FFLO-like states. Here, Y. Tokumoto et al. report experimental observation of bulk superconductivity in Ta_1.6Te, a van-der-Waals-layered QC with T_c = 1 K.

Yuki Tokumoto
Kotaro Hamano
Keiichi Edagawa
ResearchOpen Access01 Mar 2024
Nature Communications

Volume: 15, P: 1-7
Mitosis specific serine phosphorylation and downregulation of one of the focal adhesion protein, paxillin

Ryuji Yamaguchi
Yuichi Mazaki
Hisataka Sabe
Research09 Oct 1997
Oncogene

Volume: 15, P: 1753-1761
New Sesquicillins, Insecticidal Antibiotics Produced by Albophoma sp. FKI-1778

Ryuji Uchida
Rie Imasato
Satoshi Ōmura
Research01 Jun 2005
The Journal of Antibiotics

Volume: 58, P: 397-404
Electrophoretic variants of blood proteins in Japanese

Chiyoko Satoh
Norio Takahashi
Ryuji Hazama
Research01 Sept 1984
Japanese Journal of Human Genetics

Volume: 29, P: 287-310
Electrophoretic variants of blood proteins in Japanese I. Phosphoglucomutase-2 (PGM2)

Chiyoko Satoh
Norio Takahashi
Keiko Iwamoto
Research01 Jun 1984
Japanese journal of human genetics

Volume: 29, P: 89-104
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
A novel missense mutation of COL5A2 in a patient with Ehlers–Danlos syndrome

Miki Watanabe
Ryuji Nakagawa
Issei Imoto
ResearchOpen Access15 Sept 2016
Human Genome Variation

Volume: 3, P: 1-3
Exome-first approach identified a novel gloss deletion associated with Lowe syndrome

Miki Watanabe
Ryuji Nakagawa
Issei Imoto
ResearchOpen Access10 Nov 2016
Human Genome Variation

Volume: 3, P: 1-4
Reproducible production and image-based quality evaluation of retinal pigment epithelium sheets from human induced pluripotent stem cells

Ke Ye
Yuto Takemoto
Fumitaka Osakada
ResearchOpen Access01 Sept 2020
Scientific Reports

Volume: 10, P: 1-15
Tumor microenvironment-mediated immune profiles and efficacy of anti-PD-L1 antibody plus chemotherapy stratified by DLL3 expression in small-cell lung cancer

Masayuki Shirasawa
Tatsuya Yoshida
Yuichiro Ohe
Research20 Sept 2023
British Journal of Cancer

Volume: 129, P: 2003-2013
Role of transforming growth factor-β1 in regulating adipocyte progenitors

Nguyen Quynh Phuong
Muhammad Bilal
Kazuyuki Tobe
ResearchOpen Access17 Jan 2025
Scientific Reports

Volume: 15, P: 1-12
Correction: Tumor microenvironment-mediated immune profiles and efficacy of anti-PD-L1 antibody plus chemotherapy stratified by DLL3 expression in small-cell lung cancer

Masayuki Shirasawa
Tatsuya Yoshida
Yuichiro Ohe
Amendments and Corrections03 Nov 2023
British Journal of Cancer

Volume: 129, P: 2034
Novel large deletion involving EVC and EVC2 in Ellis–van Creveld syndrome

Hiroki Sato
Kenichi Suga
Ryuji Nakagawa
ResearchOpen Access17 May 2022
Human Genome Variation

Volume: 9, P: 1-4
Assessment of catabolic state in infants with the use of urinary titin N-fragment

Sachiyo Fukushima
Nobuto Nakanishi
Masafumi Matsuo
Research17 Jul 2021
Pediatric Research

Volume: 91, P: 1748-1753
Molecular diagnosis of an infant with TSC2/PKD1 contiguous gene syndrome

Keita Osumi
Kenichi Suga
Shoji Kagami
ResearchOpen Access16 Jul 2020
Human Genome Variation

Volume: 7, P: 1-5
A novel frameshift mutation of CHD7 in a Japanese patient with CHARGE syndrome

Tomohiro Kohmoto
Miki Shono
Issei Imoto
ResearchOpen Access07 Apr 2016
Human Genome Variation

Volume: 3, P: 1-3
Detection of 1p36 deletion by clinical exome-first diagnostic approach

Miki Watanabe
Yasunobu Hayabuchi
Issei Imoto
ResearchOpen Access12 May 2016
Human Genome Variation

Volume: 3, P: 1-4
Refinement of a locus for autosomal dominant hereditary motor and sensory neuropathy with proximal dominancy (HMSN-P) and genetic heterogeneity

Kouji Maeda
Ryuji Kaji
Gen Tamiya
Research02 Oct 2007
Journal of Human Genetics

Volume: 52, P: 907-914
Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy

Mariko Taniguchi-Ikeda
Kazuhiro Kobayashi
Tatsushi Toda
Research05 Oct 2011
Nature

Volume: 478, P: 127-131
Augmented O-GlcNAcylation exacerbates right ventricular dysfunction and remodeling via enhancement of hypertrophy, mitophagy, and fibrosis in mice exposed to long-term intermittent hypoxia

The impact of intermittent hypoxia (1 min at 5% O₂ and 5 min at 20% O₂, 8 h/day) for 4 weeks (IH4W) in Ogt-Tg mice. Augmented O-GlcNAcylation may aggravate IH4W-induced right ventricular dysfunction and remodeling by promoting hypertrophy, mitophagy, and fibrosis via GSK-3β inactivation, increased p-Drp-1/MFN2 ratio, and Smad2 activation, respectively.

Shunichi Yokoe
Tetsuya Hayashi
Michio Asahi
Research14 Nov 2022
Hypertension Research

Volume: 46, P: 667-678
Decadal–centennial-scale solar-linked climate variations and millennial-scale internal oscillations during the Early Cretaceous

Hitoshi Hasegawa
Nagayoshi Katsuta
Takeshi Nakagawa
ResearchOpen Access19 Dec 2022
Scientific Reports

Volume: 12, P: 1-16
New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942: II. structure elucidation

Narihiro Ugaki
Hiroyuki Yamazaki
Hiroshi Tomoda
Research30 Nov 2011
The Journal of Antibiotics

Volume: 65, P: 21-24
Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 1

Issei Imoto
Masako Saito
Kiyoshi Masuda
ResearchOpen Access05 May 2021
Scientific Reports

Volume: 11, P: 1-12
PD-L1 expression, tumor-infiltrating lymphocytes, mismatch repair deficiency, EGFR alteration and HPV infection in sinonasal squamous cell carcinoma

Takahiro Hongo
Hidetaka Yamamoto
Yoshinao Oda
Research03 Jul 2021
Modern Pathology

Volume: 34, P: 1966-1978
Neuropeptide receptor genes GHSR and NMUR1 are candidate epigenetic biomarkers and predictors for surgically treated patients with oropharyngeal cancer

Kiyoshi Misawa
Masato Mima
Hiroyuki Mineta
ResearchOpen Access23 Jan 2020
Scientific Reports

Volume: 10, P: 1-11
Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice

Takatoshi Nakagawa
Yuichi Furukawa
Michio Asahi
Research13 Aug 2019
Hypertension Research

Volume: 42, P: 1858-1871
A genome-wide association study identifies three new risk loci for Kawasaki disease

Yoshihiro Onouchi and colleagues report the results of a genome-wide association study of Kawasaki disease. They identify three new risk loci, all mapping near genes previously implicated in adult-onset autoimmune diseases.

Yoshihiro Onouchi
Kouichi Ozaki
Adriana H Tremoulet
Research25 Mar 2012
Nature Genetics

Volume: 44, P: 517-521
New verticilides, inhibitors of acyl-CoA:cholesterol acyltransferase, produced by Verticillium sp. FKI-2679

Taichi Ohshiro
Daisuke Matsuda
Hiroshi Tomoda
Research14 Mar 2012
The Journal of Antibiotics

Volume: 65, P: 255-262
Production of a new type of amidepsine with a sugar moiety by static fermentation of Humicola sp. FO-2942

Junji Inokoshi
Yoichi Takagi
Hiroshi Tomoda
Research27 Nov 2009
The Journal of Antibiotics

Volume: 63, P: 9-16
Production of monapinones by fermentation of the dinapinone-producing fungus Penicillium pinophilum FKI-3864 in a seawater-containing medium

Kyosuke Kawamoto
Hiroyuki Yamazaki
Hiroshi Tomoda
Research25 May 2011
The Journal of Antibiotics

Volume: 64, P: 503-508
Structures and absolute stereochemistry of dinapinones A1 and A2, inhibitors of triacylglycerol synthesis, produced by penicillium pinophilum FKI-3864

Ryuji Uchida
Satoshi Ohte
Hiroshi Tomoda
Research30 May 2012
The Journal of Antibiotics

Volume: 65, P: 419-425
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17

Search

Filter By:

Search

Quick links