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Showing 1–50 of 316 results

Advanced filters: Author: S B Rourke Clear advanced filters

The pericardium forms as a distinct structure during heart formation

The developing heart integrates several progenitor cell types. Here they show that the pericardium enveloping the heart develops among cells that form the mesothelium around inner organs and body cavities, distinct from the classic heart field.

Hannah R. Moran
Obed O. Nyarko
Christian Mosimann
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-21
Antibody-mediated enhancement of Flavivirus replication in macrophage-like cell lines

J. S. M. Peiris
J. S. Porterfield
Research01 Nov 1979
Nature

Volume: 282, P: 509-511
The Conduit Artery Functional Endpoint (CAFE) study in ASCOT

B Williams
M O’Rourke
Research18 Mar 2002
Journal of Human Hypertension

Volume: 15, P: S69-S73
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

Maximilian Zenk
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial

As presented at the 2025 ASCO Annual Meeting, intracerebroventricular infusion of bivalent CAR T cells targeting EGFR and IL-13Rα2 in patients with multifocal, recurrent glioblastoma was feasible and well tolerated, with the maximum tolerated dose identified, one patient with a partial response and one patient with durable stable disease.

Stephen J. Bagley
Arati S. Desai
Donald M. O’Rourke
Research01 Jun 2025
Nature Medicine

Volume: 31, P: 2778-2787
Effect of Disseminated Lupus Erythematosus Sera on the Respiratory Activity of Guinea-Pig Leucocytes

A. E. FRUEHAN
A. J. SBARRA
T. B. BAYLES
Research17 Sept 1966
Nature

Volume: 211, P: 1269-1272
Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats

Christopher Dubay
Madeleine Vincent
G. Mark Lathrop
Research01 Apr 1993
Nature Genetics

Volume: 3, P: 354-357
Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

Yew S. Ho
Lora Swenson
Zygmunt S. Derewenda
Research02 Jan 1997
Nature

Volume: 385, P: 89-93
Superantigen implicated in dependence of HIV-1 replication in T cells on TCR V β expression

Jeffrey Laurence
Andrew S. Hodtsev
David N. Posnett
Research16 Jul 1992
Nature

Volume: 358, P: 255-259
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9

The role of microglia in amyotrophic lateral sclerosis (ALS) is unclear. Here, the authors show that iPSC microglia from C9orf72-ALS patients are toxic to motor neurons and identify microglial MMP9 as a potential therapeutic target.

Björn F. Vahsen
Sumedha Nalluru
Kevin Talbot
ResearchOpen Access22 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Effects of Nifedipine on Systemic and Pulmonary Vascular Impedance in Subjects Undergoing Cardiac Catheterization

Toshitaka Noda
Toshio Yaginuma
Saichi Hosoda
Research01 Jul 2006
Hypertension Research

Volume: 29, P: 505-513
Treatment of malignant hypercalcaemia with aminohexane bisphosphonate (neridronate)

NP O'Rourke
EV McCloskey
JA Kanis
Research01 May 1994
British Journal of Cancer

Volume: 69, P: 914-917
Favourable effects on arterial wave reflection and pulse pressure amplification of adding angiotensin II receptor blockade in resistant hypertension

A Mahmud
J Feely
Research06 Sept 2000
Journal of Human Hypertension

Volume: 14, P: 541-546
Blood Levels of Drug at the Equilibrium State after Multiple Dosing

J. G. WAGNER
J. I. NORTHAM
O. S. CARPENTER
Research18 Sept 1965
Nature

Volume: 207, P: 1301-1302
Effects of Seed Germination-stimulants on the Witchweed Striga euphrasioides (Vahl) Benth.

N. S. RANGASWAMY
T. S. RANGAN
Research23 Apr 1966
Nature

Volume: 210, P: 440-441
Influence of Herbicides on Respiration of Young Pinus Seedlings

S. SASAKI
T. T. KOZLOWSKI
Research23 Apr 1966
Nature

Volume: 210, P: 439-440
Insecticidal Synergism with Valone

P. S. HEWLETT
Research16 Jan 1954
Nature

Volume: 173, P: 132
Electron Spin Resonance in Hydrogen Peroxide–Water Solutions at 90° K. irradiated with Ultra-Violet Light

ROBERT C. SMITH
S. J. WYARD
Research16 Apr 1960
Nature

Volume: 186, P: 226-228
Brain-wide neuronal circuit connectome of human glioblastoma

A study leveraging transsynaptic tracing demonstrates rapid and extensive integration of human glioblastoma organoids into the mouse brain.

Yusha Sun
Xin Wang
Hongjun Song
Research16 Jan 2025
Nature

Volume: 641, P: 222-231
Cytopathic Effects of the Parainfluenza Virus SV₅ in Vero Cells

JOHAG S. RHIM
KLAUS SCHELL
Research21 Oct 1967
Nature

Volume: 216, P: 271-272
Determination of Switching-off and Switching-on Time of Overall Nuclear RNA Synthesis

Y. DOIDA
S. OKADA
Research21 Oct 1967
Nature

Volume: 216, P: 272-273
Accelerated regrowth of non-small-cell lung tumours after induction chemotherapy

S Y El Sharouni
H B Kal
J J Battermann
ResearchOpen Access12 Dec 2003
British Journal of Cancer

Volume: 89, P: 2184-2189
Monoclonal anti-Fc receptor IgG blocks antibody enhancement of viral replication in macrophages

J. S. M. Peiris
S. Gordon
J. S. Porterfield
Research15 Jan 1981
Nature

Volume: 289, P: 189-191
Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies

In an analysis of long-term safety events in 783 patients treated with T cell therapy in 38 trials, 2.3% of patients developed second primary malignancies, and vector integration analyses revealed no pathological insertions.

Julie K. Jadlowsky
Elizabeth O. Hexner
Joseph A. Fraietta
Research20 Jan 2025
Nature Medicine

Volume: 31, P: 1134-1144
Antibody-enhanced dengue virus infection in primate leukocytes

S. B. HALSTEAD
E. J. O'ROURKE
Research24 Feb 1977
Nature

Volume: 265, P: 739-741
Cloning and endonuclease mapping of the hepatitis B viral genome

JOHN J. SNINSKY
ALEEM SIDDIQUI
STANLEY N. COHEN
Research24 May 1979
Nature

Volume: 279, P: 346-348
Protein tyrosine kinase PYK2 involved in Ca²⁺-induced regulation of ion channel and MAP kinase functions

S. Lev
H. Moreno
J. Schlessinger
Research31 Aug 1995
Nature

Volume: 376, P: 737-745
Synergistic optimization of combustion chamber design and hydrogen injection strategies for ultra-lean combustion in hydrogen engines

Zhaoming Huang
Tianyu Zhu
Rasha H. Ahmed
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-18
Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease

Matthew J. Pollman
Jennifer L. Hall
Gary H. Gibbons
Research01 Feb 1998
Nature Medicine

Volume: 4, P: 222-227
A core nucleosome surface crucial for transcriptional silencing

Jeong-Hyun Park
Michael S. Cosgrove
Jef D. Boeke
Research16 Sept 2002
Nature Genetics

Volume: 32, P: 273-279
Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results

In an interim analysis of an ongoing phase 1 trial of CAR T cells targeting EGFR and IL13Ra2 in patients with multifocal, recurrent glioblastoma, intrathecal delivery is feasible and well tolerated, with some reductions seen in tumor size.

Stephen J. Bagley
Meghan Logun
Donald M. O’Rourke
Research13 Mar 2024
Nature Medicine

Volume: 30, P: 1320-1329
A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity

Richard E. Straub
Charles J. MacLean
Kenneth S. Kendler
Research01 Nov 1995
Nature Genetics

Volume: 11, P: 287-293
Chromosome Number of Marsilea

P. N. MEHRA
D. S. LOYAL
Research22 Feb 1958
Nature

Volume: 181, P: 577
Vitamin C from Green Tomatoes

FRANK WOKES
JOAN G. ORGAN
Research31 Oct 1942
Nature

Volume: 150, P: 523-524
A structure-based approach to designing synthetic CD8α peptides that can inhibit cytotoxic T-lymphocyte responses

Swati Choksi
Bradford A. Jameson
Robert Korngold
Research01 Mar 1998
Nature Medicine

Volume: 4, P: 309-314
Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men

A Mahmud
M Hennessy
J Feely
Research12 Oct 2001
Journal of Human Hypertension

Volume: 15, P: 707-713
Cooling positronium to ultralow velocities with a chirped laser pulse train

The one-dimensional laser cooling of positronium enables testing of quantum electrodynamics and could realize Bose–Einstein condensation in positronium.

K. Shu
Y. Tajima
K. Yoshioka
ResearchOpen Access11 Sept 2024
Nature

Volume: 633, P: 793-797
Search for strange matter by Rutherford backscattering

M. Brügger
K. Lützenkirchen
U. Smilansky
Research02 Feb 1989
Nature

Volume: 337, P: 434-436
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

ALT telomeres experience DNA damage that may drive recombination-based telomere elongation. Here, the authors reveal that FANCM plays a critical role in the suppression of ALT activity through its interaction with the BTR (BLM-TOP3A-RMI) complex.

Robert Lu
Julienne J. O’Rourke
Hilda A. Pickett
ResearchOpen Access28 May 2019
Nature Communications

Volume: 10, P: 1-14
Io’s tidal response precludes a shallow magma ocean

By measuring the tidal deformation of Io as it orbits Jupiter using Juno Doppler and historically available data, the hypothesis of a shallow global magma ocean in Io is shown to be false.

R. S. Park
R. A. Jacobson
S. J. Bolton
ResearchOpen Access12 Dec 2024
Nature

Volume: 638, P: 69-73
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers

We evaluate the effects in humans of interleukin-15 co-expression on glypican-3 (GPC3) chimeric antigen receptor (CAR) T cells and demonstrate that IL-15 increases the expansion, intratumoural survival and antitumour activity of GPC3 (expressed in a group of solid cancers) CAR T cells.

David Steffin
Nisha Ghatwai
Andras Heczey
Research27 Nov 2024
Nature

Volume: 637, P: 940-946
Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

B. Margolis
P. Hu
J. Schlessinger
Research05 Mar 1992
Nature

Volume: 356, P: 71-74
Urban water supply systems’ resilience under earthquake scenario

Mo’Tamad H. Bata
Rupp Carriveau
David S.-K. Ting
ResearchOpen Access29 Nov 2022
Scientific Reports

Volume: 12, P: 1-14
Continental distribution as a forcing factor for global-scale temperature

E. J. Barron
S. L. Thompson
W. W. Hay
Research16 Aug 1984
Nature

Volume: 310, P: 574-575
Glucose Uptake, Utilization, and Transfer by the Human Placenta as Functions of Maternal Glucose Concentration

S Hauguel
V Desmaizieres
J C Challier
Research01 Mar 1986
Pediatric Research

Volume: 20, P: 269-273
A combination of a particular HLA-DPβ allele and an HLA-DQ heterodimer confers susceptibility to coeliac disease

Teodorica L. Bugawan
Giovanna Angelini
Henry A. Erlich
Research08 Jun 1989
Nature

Volume: 339, P: 470-473
The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein

Bih-Hwa Shieh
Mark A. Stamnes
Charles S. Zuker
Research02 Mar 1989
Nature

Volume: 338, P: 67-70
Fitness costs of resource overlap among coexisting bird species

Thomas E. Martin
Research28 Mar 1996
Nature

Volume: 380, P: 338-340
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

M. Rozakis-Adcock
J. McGlade
T. Pawson
Research17 Dec 1992
Nature

Volume: 360, P: 689-692
Defining the extracellular matrix for targeted immunotherapy in adult and pediatric brain cancer

Zoe I. Day
Samuel Roberts-Thomson
Misty R. Jenkins
ResearchOpen Access14 Jun 2025
npj Precision Oncology

Volume: 9, P: 1-14

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