Nature Search

Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
New Aromatic Ring-Splitting Enzyme, Protocatechuic Acid-4:5-Oxygenase

R. B. CAIN
Research03 Mar 1962
Nature

Volume: 193, P: 842-844
A rapid and reference-free imputation method for low-cost genotyping platforms

Vinh Chi Duong
Giang Minh Vu
Tham Hong Hoang
ResearchOpen Access27 Dec 2023
Scientific Reports

Volume: 13, P: 1-10
Telomerase is strongly activated in hepatocellular carcinoma but not in chronic hepatitis and cirrhosis

Young Min Park
Jong Young Choi
Boo Sung Kim
ResearchOpen Access01 Mar 1998
Experimental & Molecular Medicine

Volume: 30, P: 35-40
Potential for small and micro modular reactors to electrify developing regions

A new study assesses global small-scale nuclear power reactor deployment suitability, finding that reactors in the 1–50 MWe range could serve 70.9% of the population living in regions without night-time light. However, governance and economic issues eliminate 95% of the potential market.

G. F. L’Her
R. S. Kemp
M. R. Deinert
Research19 Apr 2024
Nature Energy

Volume: 9, P: 725-734
The mitotic STAG3–cohesin complex shapes male germline nucleome

Nagano et al. identify the third mitotic cohesin complex, STAG3–cohesin, which, with its unique biophysical properties, weakens insulation and rewires regulatory interactions of spermatogonial stem cells, shaping the male germline nucleome.

Masahiro Nagano
Bo Hu
Mitinori Saitou
Research25 Aug 2025
Nature Structural & Molecular Biology

P: 1-16
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
Limb muscle mass and phase angle asymmetry in 8-year-old children

Masanori Wako
Taro Fujimaki
Tadao Ooka
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-6
Conversion of Cyclamate to Cyclohexylamine in Rats

B. L. OSER
S. CARSON
R. C. SONDERS
Research12 Oct 1968
Nature

Volume: 220, P: 178-179
Blumgart anastomosis reduces the incidence of pancreatic fistula after pancreaticoduodenectomy: a systematic review and meta-analysis

Zhenlu Li
Ailin Wei
Weiming Hu
ResearchOpen Access21 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
Primordial rotating disk composed of at least 15 dense star-forming clumps at cosmic dawn

A strongly lensed galaxy at redshift z ≈ 6 is resolved into at least 15 star-forming clumps embedded in a rotating disk. Clump formation in this system, which is not predicted by cosmological zoom-in simulations, may be driven by disk instabilities with weak feedback, rather than past mergers.

S. Fujimoto
M. Ouchi
H. Yajima
Research07 Aug 2025
Nature Astronomy

P: 1-15
Degradation of the Benzene Nucleus by Bacteria

S. DAGLEY
P. J. CHAPMAN
J. M. WOOD
Research23 May 1964
Nature

Volume: 202, P: 775-778
Carbon Compounds in Apollo 11 Lunar Samples

BARTHOLOMEW NAGY
WARD M. SCOTT
HAROLD C. UREY
Research14 Mar 1970
Nature

Volume: 225, P: 1028-1032
Essential roles of the Fas ligand in the development of hepatitis

Toru Kondo
Takashi Suda
Shigekazu Nagata
Research01 Apr 1997
Nature Medicine

Volume: 3, P: 409-413
Passage of Antigens across the Vascular Barrier of the Thymus

KAUKO KOUVALAINEN
DAVID GITLIN
Research06 May 1967
Nature

Volume: 214, P: 592-593
Occultation observations of compact radio sources through comet Halley's plasma tail

S. Ananthakrishnan
P. K. Manoharan
V. R. Venugopal
Research22 Oct 1987
Nature

Volume: 329, P: 698-700
Polyacrylamide Gel Electrophoresis of Highly Purified Chick Interferon

K. H. FANTES
I. G. S. FURMINGER
Research07 Oct 1967
Nature

Volume: 216, P: 71-72
Frequency-dependent selection due to kinetic differences between allozymes

BRYAN CLARKE
F. W. ALLENDORF
Research21 Jun 1979
Nature

Volume: 279, P: 732-734
Amino acid substitutions in two functional mutants of yeast alcohol dehydrogenase

CHRISTOPHER WILLS
HANS JÖRNVALL
Research21 Jun 1979
Nature

Volume: 279, P: 734-736
Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure

An air-compressing intermittent-pressure method enables the fabrication of transplantable thick tissues displaying vascularization and a high protein secretion capacity, with potential regenerative medicine applications.

Misako Katsuura
Jun Homma
Tatsuya Shimizu
ResearchOpen Access08 Feb 2025
Communications Biology

Volume: 8, P: 1-17
Protection of savings by reducing the salience of opposing errors

Mousa Javidialsaadi
Scott T. Albert
Jinsung Wang
ResearchOpen Access20 Aug 2025
npj Science of Learning

Volume: 10, P: 1-13
Variation with Temperature of the Magnetic Susceptibility of Some Transition Elements

H. KOJIMA
R. S. TEBBLE
D. E. G. WILLIAMS
Research09 Jan 1960
Nature

Volume: 185, P: 90-91
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Reframing cell therapy for cancer

Technologies for engineering immune cells to recognize features on cancer cells are transforming oncology. Synthetic biologists now expand this approach by conferring therapeutic functions to nonimmune cells and by programming cells to sense and respond to a new class of physiological cues.

Taylor B Dolberg
Patrick S Donahue
Joshua N Leonard
News & Views14 Feb 2018
Nature Chemical Biology

Volume: 14, P: 204-205
Truncated midkine as a marker of diagnosis and detection of nodal metastases in gastrointestinal carcinomas

K Aridome
S Takao
T Muramatsu
Research01 Aug 1998
British Journal of Cancer

Volume: 78, P: 472-477
Activation of protein kinase C augments evoked transmitter release

Roy Shapira
Shai D. Silberberg
Rami Rahamimoff
Research01 Jan 1987
Nature

Volume: 325, P: 58-60
Research on the difference of stroke characteristics and stroke effect between different stroke duration of table tennis players

Jiajie Tian
Yi Xiao
ResearchOpen Access25 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Cross-national analysis of social determinants of frailty among middle-aged and older adults: a machine learning study in the USA, England, and China

Yan Luo
Mengzhuo Guo
Qingpeng Zhang
ResearchOpen Access30 May 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-11
Organ alchemy: producing insulin in the liver

Expressing pancreatic transcription factors in the liver drives the formation of insulin-producing cells and normalizes blood glucose levels in a mouse model of diabetes (pages 596–603).

Kenneth S. Polonsky
Graeme I. Bell
News & Views01 May 2003
Nature Medicine

Volume: 9, P: 504-505
Gene therapy for aromatic L-amino acid decarboxylase deficiency by MR-guided direct delivery of AAV2-AADC to midbrain dopaminergic neurons

Aromatic L-amino acid decarboxylase deficiency (AADC) is a rare neurodevelopmental disorder. Here the authors describe a clinical trial of MR-guided delivery of AAV2-AADC for the treatment of AADC.

Toni S. Pearson
Nalin Gupta
Krystof S. Bankiewicz
ResearchOpen Access12 Jul 2021
Nature Communications

Volume: 12, P: 1-12
Limits on the nucleus of Halley's Comet

Michael J. S. Belton
Harvey Butcher
Research15 Jul 1982
Nature

Volume: 298, P: 249-251
Attenuation of Stimulus Sensitivity induced by Scopolamine

DAVID M. WARBURTON
KENNETH BROWN
Research12 Mar 1971
Nature

Volume: 230, P: 126-127
Phylogenetic trees support the coevolution of parasites and their hosts

Mark S. Hafner
Steven A. Nadler
Research17 Mar 1988
Nature

Volume: 332, P: 258-259
No evidence for frequency-dependent selection acting between clones of the water flea, Daphnia magna

J F Y Brookfield
Research01 Dec 1981
Heredity

Volume: 47, P: 297-315
Volume Rectification in Zincite

S. R. KHASTGIR
S. K. R. TOLPADI
S. C. MITRA
Research28 Jul 1951
Nature

Volume: 168, P: 162-163
MYTHO is a novel regulator of skeletal muscle autophagy and integrity

Here, the authors identify a novel regulator of autophagy, skeletal muscle mass and integrity named MYTHO. Silencing MYTHO protects against muscle atrophy in a wide range of acute catabolic conditions, while prolonged silencing causes a severe myopathy.

Jean-Philippe Leduc-Gaudet
Anais Franco-Romero
Gilles Gouspillou
ResearchOpen Access02 Mar 2023
Nature Communications

Volume: 14, P: 1-20
Submerged Culture Production of Diphtheria Toxin

F. V. LINGGOOD
A. C. MATTHEWS
T. R. SHARLAND
Research18 Sept 1954
Nature

Volume: 174, P: 557
Stability of Epidote Minerals

W. S. FYFE
Research06 Aug 1960
Nature

Volume: 187, P: 497
Haploidy or diploidy: which is better?

Alexey S. Kondrashov
James F. Crow
Research23 May 1991
Nature

Volume: 351, P: 314-315
Dart of an Extinct Mollusc

ALEX. COMFORT
Research22 Feb 1947
Nature

Volume: 159, P: 270-271
Electron Diffraction Investigation and Magnetic Measurements on Nickel (II) Bisacetylacetone

S. SHIBATA
M. KISHITA
M. KUBO
Research09 Feb 1957
Nature

Volume: 179, P: 320-321
The structure and function of the ghrelin receptor coding for drug actions

This study reveals how anamorelin, a superagonist targeting the ghrelin receptor, works compared to other drugs. Structural insights into ligand binding and genetic variations offer a framework for personalized therapies

Yuki Shiimura
Dohyun Im
Ikuo Masuho
Research20 Jan 2025
Nature Structural & Molecular Biology

Volume: 32, P: 531-542
Ferromagnetic Resonance in Ferrites

P. A. MILES
Research24 Jul 1954
Nature

Volume: 174, P: 177-178
Pro-efferocytic nanotherapies reduce vascular inflammation without inducing anemia in a large animal model of atherosclerosis

Systemic blockade of CD47 showed promising results for treating atherosclerosis but induces anemia. Here, the authors show that macrophage-specific nanoparticles promoting efferocytosis reduce apoptotic cell accumulation and inflammation in a porcine model of atherosclerosis without causing anemia.

Sharika Bamezai
Yapei Zhang
Nicholas J. Leeper
ResearchOpen Access13 Sept 2024
Nature Communications

Volume: 15, P: 1-13
Give in the filaments

Malcolm Irving
News & Views02 Mar 1995
Nature

Volume: 374, P: 14-15
Identification of six novel MYH9 mutations and genotype–phenotype relationships in autosomal dominant macrothrombocytopenia with leukocyte inclusions

S. Kunishima
T. Matsushita
H. Saito
Research01 Dec 2001
Journal of Human Genetics

Volume: 46, P: 722-729
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
Stable equilibria under stabilising selection in the absence of dominance

J S Gale
M J Kearsey
Research01 Nov 1968
Heredity

Volume: 23, P: 553-561
Demonstration of nuclear gamma-ray polarimetry based on a multi-layer CdTe Compton camera

S. Go
Y. Tsuzuki
T. Takahashi
ResearchOpen Access09 Feb 2024
Scientific Reports

Volume: 14, P: 1-9

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