Nature Search

Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas

April A. Apfelbaum
Eric Morin
Pratiti Bandopadhayay
Amendments and CorrectionsOpen Access09 Oct 2025
Nature Communications

Volume: 16, P: 1
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors

Simultaneous activation of Wnt and Shh pathways in murine neural precursor cells results in the formation of embryonal tumors with multilayered rosettes (ETMR) that recapitulate the histological and molecular features of human tumors. This novel mouse model represents a platform for evaluating therapeutic approaches for this rare malignant pediatric brain tumor, and provides novel insights into the cell of origin and molecular mechanisms driving the disease.

Julia E Neumann
Annika K Wefers
Ulrich Schüller
Research11 Sept 2017
Nature Medicine

Volume: 23, P: 1191-1202
All-optical phase modulation in a cavity-polariton Mach–Zehnder interferometer

Quantum fluids such as cavity-polaritons show nonlinear optical properties of interest in applications such as quantum optics. Here, Sturm and colleagues demonstrate an optical control of the phase of a polariton flow, and make use of this to realize a compact exciton–polariton interferometer.

C. Sturm
D. Tanese
J. Bloch
ResearchOpen Access11 Feb 2014
Nature Communications

Volume: 5, P: 1-7
Glial reactivity and cognitive decline follow chronic heterochromatin loss in neurons

Heterochromatin loss has been linked to aging and neurodegeneration. Here, the authors show that combined loss of HP1β and HP1γ in neurons results in de-repressesion of endogenous retroviruses, inflammation in glia including accumulation of complement C3, dendritic loss, and cognitive decline in mice.

A. G. Newman
J. Sharif
V. Tarabykin
ResearchOpen Access08 Aug 2025
Nature Communications

Volume: 16, P: 1-20
A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas

A subset of pediatric gliomas harbour alterations in fibroblast growth factor receptor (FGFR)-family proteins. Here, the authors characterise the genomic landscape of 11,635 gliomas across ages and use isogenic model systems to explore the underlying biology of FGFR1-altered gliomas and potential therapeutic vulnerabilities.

April A. Apfelbaum
Eric Morin
Pratiti Bandopadhayay
ResearchOpen Access31 Jul 2025
Nature Communications

Volume: 16, P: 1-23
Community assessment of methods to deconvolve cellular composition from bulk gene expression

Deconvolution methods infer levels of immune infiltration from bulk expression of tumour samples. Here, authors assess 6 published and 22 community-contributed methods via a DREAM Challenge using in vitro and in silico transcriptional profiles of admixed cancer and healthy immune cells.

Brian S. White
Aurélien de Reyniès
Andrew J. Gentles
ResearchOpen Access27 Aug 2024
Nature Communications

Volume: 15, P: 1-22
Autoradiographic Investigation of Tissues after Primary and Multiple Antigenic Stimulation of Rabbits

JUSTINE S. GARVEY
DAN H. CAMPBELL
Research19 Mar 1966
Nature

Volume: 209, P: 1201-1202
Artificial Activation of the Egg in a Gynogenetic Spider Beetle

ANN R. SANDERSON
J. JACOB
Research22 Jun 1957
Nature

Volume: 179, P: 1300
Satellite and ship studies of coccolithophore production along a continental shelf edge

P. M. Holligan
M. Viollier
M. Champagne-Philippe
Research28 Jul 1983
Nature

Volume: 304, P: 339-342
Polymorphism and Parthenogenesis in a Ptinid Beetle

B. P. MOORE
G. E. WOODROFFE
ANN R. SANDERSON
Research05 May 1956
Nature

Volume: 177, P: 847-848
A prognostic neural epigenetic signature in high-grade glioma

A neural epigenetic signature detectable via plasma analyses is prognostic in patients with glioblastoma, resembling an oligodendrocyte-progenitor- and neuronal-progenitor-cell-like state and showing increased neuro-to-glioma synapse formation.

Richard Drexler
Robin Khatri
Franz L. Ricklefs
ResearchOpen Access17 May 2024
Nature Medicine

Volume: 30, P: 1622-1635
Genomic reanalysis of a pan-European rare-disease resource yields new diagnoses

This flagship study from the European Solve-Rare Diseases Consortium presents a diagnostic framework including bioinformatic analysis of clinical, pedigree and genomic data coupled with expert panel review, leading to 500 new diagnoses in a cohort of 6,000 families with suspected rare diseases.

Steven Laurie
Wouter Steyaert
Alexander Hoischen
ResearchOpen Access17 Jan 2025
Nature Medicine

Volume: 31, P: 478-489
Infectious C-type virus isolated from a baboon placenta

Raoul E. Benveniste
Michael M. Lieber
Seymour S. Kalter
Research01 Mar 1974
Nature

Volume: 248, P: 17-20
Diabetogenic Action of Pure Anterior Pituitary Growth Hormone

P. M. COTES
E. REID
F. G. YOUNG
Research06 Aug 1949
Nature

Volume: 164, P: 209-211
Imaging the structure of the trimer systems ⁴He₃ and ³He⁴He₂

Helium is an atom of great scientific interest, yet much debate exists surrounding the shape its molecules form. Here Voigtsberger et al. present experimental results imaging the wavefuction of ⁴He₃ and ³He₄He₂ trimer systems, which suggest that ⁴He₃ is a random cloud while ³He₄He₂is a quantum halo state.

J. Voigtsberger
S. Zeller
R. Dörner
Research09 Dec 2014
Nature Communications

Volume: 5, P: 1-6
Velocity of Electron Pulses

L. L. WHYTE
D. L. RICHARDS
D. GABOR
Research28 Aug 1954
Nature

Volume: 174, P: 398-399
Bowers graben and associated tectonic features cross northern Victoria Land, Antarctica

E. Stump
M. G. Laird
K. E. Lapham
Research28 Jul 1983
Nature

Volume: 304, P: 334-336
Detection of metastable electronic states by Penning trap mass spectrometry

Penning trap mass spectrometry is used to measure the electronic transition energy from a long-lived metastable state to the ground state in highly charged rhenium ions with a precision of 10⁻¹¹.

R. X. Schüssler
H. Bekker
K. Blaum
Research06 May 2020
Nature

Volume: 581, P: 42-46
Accurate diagnosis of pediatric brain cancers

Integrative approaches continue to improve diagnostic accuracy for pediatric brain cancers, but much more is needed from researchers, governments and regulators if precision medicine with curative treatments are to become a reality.

Pratiti Bandopadhayay
Elaine R. Mardis
News & Views17 Mar 2023
Nature Medicine

Volume: 29, P: 787-788
Snow-sensing fleet to unlock water's icy secrets

Airborne experiments aim to fill in the blanks of global water resources as the climate changes.

Alexandra Witze
News06 Apr 2016
Nature

Volume: 532, P: 17
Next-generation phenotyping integrated in a national framework for patients with ultrarare disorders improves genetic diagnostics and yields new molecular findings

Exome sequencing within a structured diagnostic process for rare diseases in Germany shows how facial image analysis and machine learning can guide variant prioritization and uncover many ultrarare diseases.

Axel Schmidt
Magdalena Danyel
Matias Wagner
ResearchOpen Access22 Jul 2024
Nature Genetics

Volume: 56, P: 1644-1653
Cospatial ice mapping of H₂O with CO₂ and CO across a molecular cloud with JWST/NIRCam

Using slitless spectroscopy, JWST/NIRCam has simultaneously mapped three ice species across a dense cloud along 44 lines of sight. This cospatial mapping enables the local cloud chemistry to be probed with a spatial resolution of hundreds of astronomical units, representing a step change in ice mapping.

Z. L. Smith
H. J. Dickinson
E. F. van Dishoeck
ResearchOpen Access24 Mar 2025
Nature Astronomy

Volume: 9, P: 883-894
Interpretation of Experiments on Frictional Electrification

W. R. HARPER
Research10 Mar 1951
Nature

Volume: 167, P: 400-401
Opposite voltage gating polarities of two closely related onnexins

Vytas K. Verselis
Christopher S. Ginter
Thaddeus A. Bargiello
Research24 Mar 1994
Nature

Volume: 368, P: 348-351
High-precision measurement of the atomic mass of the electron

A very precise measurement of the magnetic moment of a single electron bound to a carbon nucleus, combined with a state-of-the-art calculation in the framework of bound-state quantum electrodynamics, gives a new value of the atomic mass of the electron that is more precise than the currently accepted one by a factor of 13.

S. Sturm
F. Köhler
K. Blaum
Research19 Feb 2014
Nature

Volume: 506, P: 467-470
Author Correction: Next-generation phenotyping integrated in a national framework for patients with ultrarare disorders improves genetic diagnostics and yields new molecular findings

Axel Schmidt
Magdalena Danyel
Matias Wagner
Amendments and CorrectionsOpen Access24 Jun 2025
Nature Genetics

Volume: 57, P: 1790-1791
Salmon in Preserved Rivers

F. C. S.
Research15 Sept 1881
Nature

Volume: 24, P: 461
New Seismometer

S. E. PEAL
Research15 Sept 1881
Nature

Volume: 24, P: 461
Archaean tectonics

W. S. FYFE
Research24 May 1974
Nature

Volume: 249, P: 338
Probing QED and fundamental constants through laser spectroscopy of vibrational transitions in HD⁺

Molecular hydrogen ions, the simplest molecules in nature, constitute a benchmark system for tests of quantum electrodynamics in complex forms of matter. Here, the authors report on a laser spectroscopic frequency measurement of a transition in HD⁺in agreement with theory within 0.6 (1.1) part-per-billion.

J. Biesheuvel
J.-Ph. Karr
J. C. J. Koelemeij
ResearchOpen Access27 Jan 2016
Nature Communications

Volume: 7, P: 1-7
Thyrotrophic and Gonadotrophic Hormone Contents of Pituitaries and Blood of Dogs during the Winter and Summer

FOUAD A. SOLIMAN
Y. S. GHANEM
Research12 Jan 1957
Nature

Volume: 179, P: 102
Development, validation, and updating of prognostic models for m7G-associated genes from TAMs in lower-grade gliomas

Lei Ao
Huijun Li
Zaixiang Tang
ResearchOpen Access11 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Excretion of Inulin by Malpighian Tubules

J. A. RAMSAY
J. A. RIEGEL
Research09 Sept 1961
Nature

Volume: 191, P: 1115
Tubule Formation in Rat Brains by Monkey Kidney Cells previously grown in vitro

M. MICHAEL SIGEL
THOMAS M. SCOTTI
MANTLEY DORSEY JUN.
Research11 Oct 1958
Nature

Volume: 182, P: 1034-1035
Radioactive Samarium-145 and Promethium-145

F. D. S. BUTEMENT
Research10 Mar 1951
Nature

Volume: 167, P: 400
Induction of Polyploidy by Pulp and Disintegrating Tissues from Colchicum sp

DONTCHO KOSTOFF
Research18 Feb 1939
Nature

Volume: 143, P: 287-288
Measurement of Gamma-Ray Energies with the Scintillation Counter

E. H. BELCHER
Research11 Nov 1950
Nature

Volume: 166, P: 826-827
Protective Effect of Cysteine against Retinal Degeneration induced by lodate and by lodoacetate

ARNOLD SORSBY
RONALD HARDING
Research13 Aug 1960
Nature

Volume: 187, P: 608-609
An analysis of p53, BAX and vascular endothelial growth factor expression in node-positive rectal cancer. Relationships with tumour recurrence and event-free survival of patients treated with adjuvant chemoradiation

S Cascinu
F Graziano
G Catalano
ResearchOpen Access26 Feb 2002
British Journal of Cancer

Volume: 86, P: 744-749
Calendar of Scientific Pioneers

E. C. S.
News22 Sept 1921
Nature

Volume: 108, P: 134
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology

The integration of DNA methylation profiling and targeted sequencing with neuropathology improves the diagnostic accuracy of central nervous system tumors in a population-based cohort of more than 1,200 newly diagnosed pediatric patients.

Dominik Sturm
David Capper
David. T. W. Jones
ResearchOpen Access16 Mar 2023
Nature Medicine

Volume: 29, P: 917-926
G₀ is a major growth cone protein subject to regulation by GAP-43

Stephen M. Strittmatter
Dario Valenzuela
Mark C. Fishman
Research26 Apr 1990
Nature

Volume: 344, P: 836-841
The cool brown dwarf Gliese 229 B is a close binary

Analysis of the cool brown dwarf Gliese 229 B suggests that it is actually a close binary of two less massive brown dwarfs, explaining its low luminosity and settling the conflict between theoretical predictions and measurements.

Jerry W. Xuan
A. Mérand
J. Woillez
Research16 Oct 2024
Nature

Volume: 634, P: 1070-1074
Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

Pediatric brain cancers are lethal malignancies driven by less-differentiated stem-like cells. Here the authors show that these cells exhibit distinct mitochondrial metabolism programs with targetable vulnerabilities.

Nneka E. Mbah
Amy L. Myers
Costas A. Lyssiotis
ResearchOpen Access17 Oct 2024
Nature Communications

Volume: 15, P: 1-21
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

Shih-Feng Tsai
David I. K. Martin
Stuart H. Orkin
Research08 Jun 1989
Nature

Volume: 339, P: 446-451
Publisher Correction: Genomic reanalysis of a pan-European rare-disease resource yields new diagnoses

Steven Laurie
Wouter Steyaert
Alexander Hoischen
Amendments and CorrectionsOpen Access19 Jun 2025
Nature Medicine

Volume: 31, P: 2819-2820
Identification and characterisation of pathogenic and non-pathogenic FGF14 repeat expansions

Repeat expansions in the FGF14 gene can cause late-onset cerebellar ataxia (SCA27B), however the defining features of pathogenic expansions remain uncertain. Here, the authors compare the sequence and structure of FGF14 repeat expansions in patients and controls, leading them to suggest a lower pathogenic threshold and emphasizing the importance of sequencing the full expansion for accurate interpretation.

Lars Mohren
Friedrich Erdlenbruch
Christel Depienne
ResearchOpen Access03 Sept 2024
Nature Communications

Volume: 15, P: 1-20
Practical diagnosis of cirrhosis in non-alcoholic fatty liver disease using currently available non-invasive fibrosis tests

The practical rules for the early non-invasive diagnosis of cirrhosis in NAFLD are not well defined. Here, the authors develop and validate two diagnostic tools: a stepwise stratification algorithm including a cirrhosis group, and a risk prediction chart providing a personalized assessment of the individual probability of cirrhosis.

Jérôme Boursier
Marine Roux
Philip N. Newsome
ResearchOpen Access26 Aug 2023
Nature Communications

Volume: 14, P: 1-11
Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B

Radiation-induced gliomas (RIGs) have been reported in patients after treatment with cranial irradiation for various primary malignancies but their origin are still unclear. Here, the authors define the genomic, epigenetic and transcriptional landscape of 32 RIGs cases.

Maximilian Y. Deng
Dominik Sturm
David T. W. Jones
ResearchOpen Access20 Sept 2021
Nature Communications

Volume: 12, P: 1-11
Detailed study of a rare hyperluminous rotating disk in an Einstein ring 10 billion years ago

An extreme Einstein ring ~10,000 times as bright as the Milky Way in the infrared is studied with VLT/ERIS and ALMA, and the authors find that the lensed galaxy is a starburst with a fast-rotating disk, rather than being driven by a major merger.

Daizhong Liu
Natascha M. Förster Schreiber
Min S. Yun
ResearchOpen Access15 Jul 2024
Nature Astronomy

Volume: 8, P: 1181-1194

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