Structural and steric restrictions in polymer chains resulted in significant differences between cyclic polymers and their linear counterparts in the interfacial properties. The topological influences on the air–water interfacial activity and aggregation behavior of PEG and Pluronic surfactants were investigated. Silver nanoparticles adsorbed with cyclic PEG exhibited high dispersion stability under physiological and various conditions. This study successfully combined the biocompatibility of PEG with the antibacterial activity of silver nanoparticles. These results demonstrate that utilizing polymer topology can serve as a useful tool for designing new functional materials.
