Nature Search

Nature of the Non-Haem Iron in Ferredoxin and Rubredoxin

R. D. GILLARD
E. D. MCKENZIE
J. E. STANGROOM
Research20 Nov 1965
Nature

Volume: 208, P: 769-771
Natural and synthetic non-peptide antigens recognized by human γδ T cells

Yoshimasa Tanaka
Craig T. Morita
Barry R. Bloom
Research11 May 1995
Nature

Volume: 375, P: 155-158
Natural killer cells’ functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes

Patients with myelodysplastic syndromes (MDS) have limited therapeutic options. Here the authors show that functionally impaired NK cells contribute to immune escape of pre-malignant clones in early stage MDS and that NK adoptive cell therapy can be considered to prevent or delay the development of MDS.

Juan Jose Rodriguez-Sevilla
Irene Ganan-Gomez
Simona Colla
ResearchOpen Access11 Apr 2025
Nature Communications

Volume: 16, P: 1-14
Nature of the charge carriers in electron-doped copper oxide superconductors

J. M. Tranquada
S. M. Heald
M. Croft
Research23 Feb 1989
Nature

Volume: 337, P: 720-721
Sulfonated polybenzimidazole for low-alkalinity ion solvating membrane water electrolysis

KOH-doped membranes, so-called ion-solvating membranes (ISMs), have been used in alkaline water electrolysers but face challenges with stability and narrow operational windows. Here a non-crosslinked, partially sulfonated polybenzimidazole ISM with enhanced conductivity and stability is reported, achieving high current densities and prolonged operation.

Muhammad Mara Ikhsan
Chaeyeon Yang
Dirk Henkensmeier
ResearchOpen Access10 Oct 2025
Nature Energy

P: 1-13
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
Inhibition of formyl peptide receptor-1-mediated cell death as a therapy for lethal cutaneous drug reactions in preclinical models

This study identifies chenodeoxycholic acid as an inhibitor of formyl peptide receptor 1- mediated keratinocyte cell death, demonstrating its therapeutic potential in both in vitro human keratinocyte assays and a humanized mouse model of severe drug-induced skin reactions.

Haruna Kimura
Akito Hasegawa
Riichiro Abe
ResearchOpen Access30 Sept 2025
Nature Communications

Volume: 16, P: 1-13
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations

Polygenic risk scores can help identify individuals at higher risk of type 2 diabetes. Here, the authors characterise a multi-ancestry score across nearly 900,000 people, showing that its predictive value depends on demographic and clinical context and extends to related traits and complications.

Boya Guo
Yanwei Cai
Burcu F. Darst
ResearchOpen Access01 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

Cerebral organoids can be used to gain insights into neuropsychiatric disorders. Here the authors carry out RNAseq characterization from organoids derived from donors with autism spectrum disorder to identify associated cell type specific driver genes.

Elaine T. Lim
Yingleong Chan
George M. Church
ResearchOpen Access10 Jun 2022
Nature Communications

Volume: 13, P: 1-14
Late fluid flow in a primitive asteroid revealed by Lu–Hf isotopes in Ryugu

Analysis of samples from the asteroid Ryugu provide evidence of late fluid flow in a carbonaceous asteroid, indicating that such bodies may have retained two to three times more water than previously thought.

Tsuyoshi Iizuka
Takazo Shibuya
Hisayoshi Yurimoto
Research10 Sept 2025
Nature

Volume: 646, P: 62-67
Stratified wind from a super-Eddington X-ray binary is slower than expected

The XRISM Resolve spectrum of the galactic neutron star X-ray binary, GX 13+1, reveals one of the densest winds ever seen in absorption lines.

Marc Audard
Hisamitsu Awaki
Missagh Mehdipour
ResearchOpen Access17 Sept 2025
Nature

Volume: 646, P: 57-61
Microscopic mechanisms of deformation transfer in high dynamic range branched nanoparticle deformation sensors

Tetrapod quantum dots are promising nanoscale stress sensors because of their non-invasive sensing technique, but sensor versatility has not yet been assessed. Here the authors show that tetrapod quantum dots exhibit a large dynamic range and excellent sensing versatility in a multitude of polymers.

Shilpa N. Raja
Xingchen Ye
Robert O. Ritchie
ResearchOpen Access20 Mar 2018
Nature Communications

Volume: 9, P: 1-10
The impact of chemical reactivity on the quality and stability of RNA–LNP pharmaceuticals

Lipid nanoparticle-based delivery vehicles for mRNA are assembled from several different components. This Perspective discusses how these components react with each other and pose a particular analytical challenge that must be addressed to ensure the reproducibility, stability and safety of such drug formulations.

Tristan Kovačič
Heinrich Haas
Dan Peer
Reviews08 Oct 2025
Nature Reviews Chemistry

P: 1-13
Electrochemical cascade access to hetero[8]circulenes as potent organophotocatalysts for diverse C–X bond formations

The chemistry of hetero[8]circulenes has been limited to three main types, constrained by synthetic challenges in creating unsymmetrical variants. Herein, the authors introduce an electrochemical approach to a type of hetero[8]circulene, featuring five hexagons and three pentagons, and explore its application as an organophotocatalyst.

Ahmed S. Gabr
Mohamed S. H. Salem
Shinobu Takizawa
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-12
Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome

This study identified prevalent giant extrachromosomal elements from the human oral microbiome. The genetic and ecological analysis provides insight on the potential contribution of this element in adaptation against multiple oral environmental stressors.

Yuya Kiguchi
Nagisa Hamamoto
Yutaka Suzuki
ResearchOpen Access11 Aug 2025
Nature Communications

Volume: 16, P: 1-15
Co-option of an ancestral cloacal regulatory landscape during digit evolution

The regulatory landscape controlling Hoxd gene expression in tetrapod digit development was probably co-opted from a pre-existing cloacal regulatory mechanism, as evidenced by the effects of genetic deletion experiments in zebrafish fin, cloaca and mouse urogenital development.

Aurélie Hintermann
Christopher C. Bolt
Denis Duboule
ResearchOpen Access17 Sept 2025
Nature

P: 1-8
Clonal diversity shapes the tumour microenvironment leading to distinct immunotherapy responses in metastatic urothelial carcinoma

The role of polyclonal competition in immunotherapy response is poorly understood. Here, the authors perform multiregional sequencing of a metastatic urothelial carcinoma patient that exhibited different treatment responses to anti-PD-1 therapy at each tumour site and identify distinct cancer-related properties.

Takashi Kamatani
Kota Umeda
Tatsuhiko Tsunoda
ResearchOpen Access27 Aug 2025
Nature Communications

Volume: 16, P: 1-17
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

The genetic basis of atopic dermatitis is not fully understood. Here, the authors find 91 genetic loci associated with atopic dermatitis in a GWAS of >1million individuals, which highlight the importance of systemic immune regulation.

Ashley Budu-Aggrey
Anna Kilanowski
Lavinia Paternoster
ResearchOpen Access04 Oct 2023
Nature Communications

Volume: 14, P: 1-18
Radio Emission from the Nucleus of the Andromeda Nebula

G. G. POOLEY
S. KENDERDINE
Research17 Jun 1967
Nature

Volume: 214, P: 1190-1192
Radio Emitting Electrons in the Galaxy and the Solar Modulation of Cosmic Rays

K. C. ANAND
R. R. DANIEL
S. A. STEPHENS
Research06 Jan 1968
Nature

Volume: 217, P: 25-27
Immunochemical Characterization of Variant Long-Chain Acyl-CoA Dehydrogenase in Cultured Fibroblasts from Nine Patients with Long-Chain Acyl-CoA Dehydrogenase Deficiency

Yasuhiro Indo
Paul M Coates
Kay Tanaka
Research01 Sept 1991
Pediatric Research

Volume: 30, P: 211-215
Decoding sexually dimorphic proteomic landscapes in the context of aging and mortality

Jin, Du et al. develop a proteomic-based aging clock, called ProteAge, designed to estimate biological age and predict mortality risk using proteomics data from the UK Biobank. Findings reveal clear sex-specific differences in aging trajectories with women showing more complex, nonlinear patterns, whereas men tend to age in a more linear fashion.

Zhihao Jin
Bingying Du
Yanxia Rao
ResearchOpen Access29 Sept 2025
Communications Medicine

Volume: 5, P: 1-16
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
Rituximab-induced long-term remission in childhood-onset, uncomplicated, frequently relapsing or steroid-dependent nephrotic syndrome: a randomized, placebo-controlled trial and a follow-up study

Kazumoto Iijima
Mayumi Sako
Mari Oba
ResearchOpen Access10 Oct 2025
Scientific Reports

Volume: 15, P: 1-14
Functionally deficient UBOX5 variants and primary angle-closure glaucoma

Primary angle-closure glaucoma is a leading cause of blindness. Here, the authors identify rare deleterious variants in UBOX5 as risk factors and implicate BIP ubiquitination as a potential disease mechanism.

Zheng Li
Wee Ling Chng
Chiea Chuen Khor
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-13
Investigation on tribological and mechanical behaviour of GFRP composites with varying weight percentages of nano-graphite powders

D. Singh
R. R. Kumar
H. M. Sulfikhar Ali
ResearchOpen Access07 Oct 2025
Scientific Reports

Volume: 15, P: 1-31
Spectroscopic Investigation of Rubredoxin and Ferredoxin

N. M. ATHERTON
K. GARBETT
J. E. STANGROOM
Research01 Nov 1966
Nature

Volume: 212, P: 590-593
Is beryllium in metal-poor stars of galactic or cosmological origin?

Gerard Gilmore
Bengt Gustafsson
Poul E. Nissen
Research04 Jun 1992
Nature

Volume: 357, P: 379-384
Star quality

Japan's Nobel laureates have a celebrity status that outstrips anything seen by their contemporaries in North America or Europe. How have they balanced the desire to be a positive influence with the need to retain some privacy? David Cyranoski finds out.

David Cyranoski
News22 Jan 2004
Nature

Volume: 427, P: 282-283
Basal promoter elements as a selective determinant of transcriptional activator function

Gokul Das
Craig S. Hinkley
Winship Herr
Research13 Apr 1995
Nature

Volume: 374, P: 657-660
Localization of a gene for Fukuyama type congenital muscular dystrophy to chromosome 9q31–33

T. Toda
M. Segawa
Y. Nakamura
Research01 Nov 1993
Nature Genetics

Volume: 5, P: 283-286
Polarization Reversal of Solar Microwave Bursts

REUVEN RAMATY
STEPHEN S. HOLT
Research04 Apr 1970
Nature

Volume: 226, P: 68-69
Estimation of reference curves for brain atrophy and analysis of robustness to machine effects

Elodie Piot
Félix Renard
Maria Luisa Mandelli
ResearchOpen Access03 Oct 2025
Scientific Reports

Volume: 15, P: 1-21
Impact of prophylactic antibiotic duration on surgical site infection rate in neonatal surgery: a multicenter retrospective observational study

Tomohiro Sunouchi
Jun Fujishiro
Yutaka Matsuyama
ResearchOpen Access27 Aug 2025
Journal of Perinatology

Volume: 45, P: 1443-1449
Trust in scientists and their role in society across 68 countries

What is the state of trust in scientists around the world? To answer this question, the authors surveyed 71,922 respondents in 68 countries and found that trust in scientists is moderately high.

Viktoria Cologna
Niels G. Mede
Rolf A. Zwaan
ResearchOpen Access20 Jan 2025
Nature Human Behaviour

Volume: 9, P: 713-730
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Ancient oceans, ice sheets and the hydrological cycle on Mars

V. R. Baker
R. G. Strom
V. S. Kale
Research15 Aug 1991
Nature

Volume: 352, P: 589-594
Data-driven de novo design of super-adhesive hydrogels

A data-driven approach integrates data mining, experimentation and machine learning to design high-performance adhesive hydrogels from scratch, tailored for demanding underwater environments.

Hongguang Liao
Sheng Hu
Jian Ping Gong
ResearchOpen Access06 Aug 2025
Nature

Volume: 644, P: 89-95
New Pathways in the Oxidative Metabolism of Aromatic Compounds by Micro-Organisms

S. DAGLEY
W. CHARLES EVANS
D. W. RIBBONS
Research12 Nov 1960
Nature

Volume: 188, P: 560-566
A Molecular Model for a Sodium Pump

L. J. OPIT
J. S. CHARNOCK
Research30 Oct 1965
Nature

Volume: 208, P: 471-474
Comb-type grafted hydrogels with rapid deswelling response to temperature changes

Ryo Yoshida
Katsumi Uchida
Teruo Okano
Research16 Mar 1995
Nature

Volume: 374, P: 240-242
A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis

Plasma proteomic analysis of presymptomatic individuals with amyotrophic lateral sclerosis identifies novel disease-associated proteins and enables the development of an accurate diagnostic biomarker panel.

Ruth Chia
Ruin Moaddel
Bryan J. Traynor
ResearchOpen Access19 Aug 2025
Nature Medicine

Volume: 31, P: 3440-3450
Spiral Tissue Microarrays as Next Evolutionary Step in the High-density Tissue Microarray Technology

Takeshi Uemura Dr.
Lucian Chirieac Dr.
Ryo Ohsawa
ResearchOpen Access30 Aug 2010
Nature Precedings

P: 1
Model estimates of CO₂ emissions from soil in response to global warming

D. S. Jenkinson
D. E. Adams
A. Wild
Research23 May 1991
Nature

Volume: 351, P: 304-306
Modeling the genomic architecture of adiposity and anthropometrics across the lifespan

Body size and composition are complex traits that are challenging to characterize due to environmental and genetic influences. Here, Arehart et al. disentangle shared and distinct genetic signals underlying body size and composition.

Christopher H. Arehart
Meng Lin
Luke M. Evans
ResearchOpen Access13 Aug 2025
Nature Communications

Volume: 16, P: 1-16
Extreme weather event attribution predicts climate policy support across the world

Literature produced inconsistent findings regarding the links between extreme weather events and climate policy support across regions, populations and events. This global study offers a holistic assessment of these relationships and highlights the role of subjective attribution.

Viktoria Cologna
Simona Meiler
Amber Zenklusen
ResearchOpen Access01 Jul 2025
Nature Climate Change

Volume: 15, P: 725-735
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

Ebselen is an organoselenium drug that inhibits the SARS-CoV-2 main protease (M^pro). Here, the authors co-crystallised M^pro with ebselen and an ebselen derivative and observed an enzyme bound organoselenium covalent adduct in the crystal structures, which was also confirmed by mass spectrometry analysis.

Kangsa Amporndanai
Xiaoli Meng
S. Samar Hasnain
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-7
Molecular basis of positional memory in limb regeneration

A molecular analysis of axolotl limb regeneration has identified a positive genetic circuit that maintains posterior cell identity and can be used to reprogramme anterior cells into posterior cells.

L. Otsuki
S. A. Plattner
E. M. Tanaka
ResearchOpen Access21 May 2025
Nature

Volume: 642, P: 730-738
Hierarchy of bond stiffnesses within icosahedral-based gold clusters protected by thiolates

The hierarchy of bond stiffness may contribute to the thermal properties of metal clusters. Here, the authors use X-ray absorption spectroscopy to study the stiffness of the gold–gold and gold–sulfur bonds in a series of thiolate-protected, icosahedral-based gold clusters.

Seiji Yamazoe
Shinjiro Takano
Tatsuya Tsukuda
ResearchOpen Access18 Jan 2016
Nature Communications

Volume: 7, P: 1-7

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