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npj Parkinson's Disease (4)
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Showing 1–11 of 11 results

Advanced filters: Author: Sara Violante Clear advanced filters

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Qiu et al. provide insight into the metabolic adaptations that enable breast cancer cells to proliferate in the face of glutaminolysis blockade.

Yijian Qiu
Olivia T. Stamatatos
Michael J. Lukey
Research27 Aug 2024
Nature Metabolism

Volume: 6, P: 1529-1548
A genetically encoded tool to increase cellular NADH/NAD⁺ ratio in living cells

A soluble bacterial transhydrogenase from Escherichia coli (EcSTH) was validated as a genetically encoded tool to induce NADH reductive stress in mammalian cells revealing unique transcriptional and metabolic signatures.

Xingxiu Pan
Mina L. Heacock
Valentin Cracan
Research26 Oct 2023
Nature Chemical Biology

Volume: 20, P: 594-604
Genomic insights of Salmonella isolated from dry fermented sausage production chains in Spain and France

Núria Ferrer-Bustins
Claire Yvon
Anna Jofré
ResearchOpen Access22 May 2024
Scientific Reports

Volume: 14, P: 1-14
Distinct metabolic requirements regulate B cell activation and germinal center responses

Sharma et al. identify an early metabolic checkpoint dependent upon lactate dehydrogenase for newly activated B cells to enter germinal centers.

Rahul Sharma
Ryan M. Smolkin
Jayanta Chaudhuri
Research26 Jun 2023
Nature Immunology

Volume: 24, P: 1358-1369
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells

The secondary bile acid 3β-hydroxy-deoxycholic (isodeoxycholic) acid, produced by gut bacteria, promotes the generation of colonic extrathymic regulatory T cells, whose immunosuppressive activities are known to be essential for intestinal health.

Clarissa Campbell
Peter T. McKenney
Alexander Y. Rudensky
Research15 Apr 2020
Nature

Volume: 581, P: 475-479
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease

Multi-ancestry genome-wide association analyses identify new risk loci for Parkinson’s disease, and fine-mapping and co-localization analyses implicate candidate genes whose expression is associated with disease susceptibility.

Jonggeol Jeffrey Kim
Dan Vitale
Ignacio Mata
ResearchOpen Access28 Dec 2023
Nature Genetics

Volume: 56, P: 27-36
Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores

Paula Saffie-Awad
Spencer M. Grant
Sara Bandres-Ciga
ResearchOpen Access03 Jul 2025
npj Parkinson's Disease

Volume: 11, P: 1-13
Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)

Lara M. Lange
Micol Avenali
Masharip Atadzhanov
Amendments and CorrectionsOpen Access13 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-3
The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

Lara M. Lange
Kristin Levine
Masharip Atadzhanov
ResearchOpen Access25 Mar 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

Clodagh Towns
Madeleine Richer
Masharip Atadzhanov
ResearchOpen Access12 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-6