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Showing 1–50 of 59 results

Advanced filters: Author: Shanshan Xiong Clear advanced filters

YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice

SARS-CoV-2 variants often exhibit immune evasion, necessitating antiviral strategies beyond vaccination. This study presents a papain-like protease (PLpro) inhibitor called YL1004, which exhibits potent, broad-spectrum antiviral activity against wild-type, Delta, and Omicron variants in vitro and in vivo.

Jinshan Nan
Huiping Shuai
Shengyong Yang
ResearchOpen Access26 Jan 2026
Nature Communications

P: 1-14
Structural insights into type-I and type-II Lamassu antiphage systems

Li et al. report the cryo-EM structures of type-I and type-II Lamassu systems in apo and double-stranded DNA-bound states, revealing the unique architecture and mechanisms of this prokaryotic antiphage system.

Ming Li
Xiaolong Zhao
Yi Zhang
Research02 Jan 2026
Nature Chemical Biology

P: 1-10
Dynamic interactions between gut microbiome and host lipidome in antenatal depression: a large longitudinal study

Fan Li
Yunhaonan Yang
Xiong-Fei Pan
Research16 Feb 2026
Molecular Psychiatry

P: 1-13
Author Correction: Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery

Bohong Chen
Tianyu Ge
Zhou Songyang
Amendments and Corrections01 Aug 2023
Nature Cell Biology

Volume: 25, P: 1384
Presence of SARS-CoV-2 in fetal organs via intraamniotic infection

Infection with SARS-CoV-2 during pregnancy may result in maternal and fetal complications. Here, the authors analyze 18 fetuses following maternal SARS-CoV-2 infection and identify distribution in fetal organs through vertical transmission.

Shengnan Wu
Linchen Tang
Liping Jin
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-10
Measuring China’s Open Sharing for scientific instruments: an ascendency analysis with benchmark use-time data

Xiaobo Wang
Shanshan Qu
ResearchOpen Access26 Sept 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-17
Zika virus disrupts steroidogenesis and impairs spermatogenesis by stalling the translation of CYP17A1 mRNA

Zika virus impairs male fertility by utilizing its NS2A protein to block the translation of CYP17A1 mRNA in Leydig cells, thereby suppressing testosterone synthesis and sperm production in vivo.

Wei Yang
Hanyu Li
Ying Wu
ResearchOpen Access22 Jul 2025
Nature Communications

Volume: 16, P: 1-20
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas

FBXO11 is identified as the F-box protein that normally targets BCL6 for degradation, and FBXO11 deletions or mutations that prevent this function and thus stabilize BCL6 are found in B-cell lymphomas.

Shanshan Duan
Lukas Cermak
Michele Pagano
Research04 Jan 2012
Nature

Volume: 481, P: 90-93
Silibinin mitigates AKI-to-CKD transition via MAPK and PI3K/AKT signaling pathways in Ischemia-Reperfusion injury

Sijin Dong
Jun Jian
Lei Wang
ResearchOpen Access18 Nov 2025
Scientific Reports

Volume: 15, P: 1-19
Superior outcomes of haploidentical hematopoietic cell transplantation over chemotherapy in AML patients 55 years or older

Lin Li
Lixia Zhu
He Huang
Research30 Mar 2025
Bone Marrow Transplantation

Volume: 60, P: 773-778
Author Correction: Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

Yubin Huang
Zhen Xu
Bo Peng
Amendments and Corrections20 Nov 2020
Nature Neuroscience

Volume: 24, P: 288
EBV miRNAs BART11 and BART17-3p promote immune escape through the enhancer-mediated transcription of PD-L1

Epstein-Barr virus (EBV)-encoded latent genes are reported to regulate PD-L1 expression to promote immune escape. Here, the authors show that EBV-encoded miRNAs EBV-miR-BART11 and EBV-miR-BART17-3p upregulate PD-L1 expression in nasopharyngeal carcinoma and gastric cancer by targeting FOXP1 and PBRM1.

Jie Wang
Junshang Ge
Zhaoyang Zeng
ResearchOpen Access14 Feb 2022
Nature Communications

Volume: 13, P: 1-21
Construction and modular implementation of the THETA cycle for synthetic CO₂ fixation

Few synthetic CO₂-fixation pathways have been tested in vivo. Now, the new-to-nature THETA cycle is designed, realized in vitro and modular implemented in vivo. This cycle involves 17 enzymes, including the two most active carboxylases known so far, to produce the central building block acetyl-CoA using CO₂.

Shanshan Luo
Christoph Diehl
Tobias J. Erb
ResearchOpen Access20 Dec 2023
Nature Catalysis

Volume: 6, P: 1228-1240
Human papillomavirus-encoded circular RNA circE7 promotes immune evasion in head and neck squamous cell carcinoma

Immune evasion is a feature of HPV-positive head and neck squamous cell carcinoma (HNSCC). Here the authors report that a circular RNA, circE7, encoded by HPV promotes immune evasion in HNSCC by promoting downregulation of galectin-9.

Junshang Ge
Yi Meng
Zhaoyang Zeng
ResearchOpen Access04 Oct 2024
Nature Communications

Volume: 15, P: 1-18
An organ-wide spatiotemporal transcriptomic and cellular atlas of the regenerating zebrafish heart

Adult zebrafish possess the ability to regenerate injured hearts through a complex orchestration of molecular and cellular activities. Here, the authors present a single cell and spatially-resolved atlas of the regenerating zebrafish heart, which serves as a valuable resource for research on heart regeneration.

Lei Li
Meina Lu
Ying Su
ResearchOpen Access19 Apr 2025
Nature Communications

Volume: 16, P: 1-20
Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery

Through a genome-wide CRISPR synthetic viability screen for PARP-inhibitor resistance, Chen and Ge et al. show that transmembrane nuclease NUMEN directs double-stranded DNA break repair pathway choice at the nuclear periphery.

Bohong Chen
Tianyu Ge
Zhou Songyang
Research15 Jun 2023
Nature Cell Biology

Volume: 25, P: 1004-1016
Holistic bursting cells store long-term memory in auditory cortex

Previous work has identified cells in L2/3 of auditory cortex which strongly respond with bursting to a specific learned chord, but not to single component tones in an auditory task. Here the authors show that these cells correlate with the behavioral relevance of the learned composite sounds.

Ruijie Li
Junjie Huang
Hongbo Jia
ResearchOpen Access07 Dec 2023
Nature Communications

Volume: 14, P: 1-14
Pulsation of electrified jet in capillary microfluidics

Xiong Li
Shanshan Wei
Tianfu Wang
ResearchOpen Access18 Jul 2017
Scientific Reports

Volume: 7, P: 1-7
Degradation mechanisms of perovskite solar cells under vacuum and one atmosphere of nitrogen

Understanding degradation mechanisms in perovskite solar cells is key to their development. Now, Guo et al. show a greater degradation of the perovskite structure and morphology for devices operated under vacuum than under nitrogen.

Renjun Guo
Dan Han
Peter Müller-Buschbaum
Research18 Oct 2021
Nature Energy

Volume: 6, P: 977-986
The genome of cultivated peanut provides insight into legume karyotypes, polyploid evolution and crop domestication

High-quality genome sequence of cultivated peanut comprising 2.54 Gb with 20 pseudomolecules and 83,709 protein-coding gene models provides insights into genome evolution and the genetic mechanisms underlying seed size and leaf resistance in peanut.

Weijian Zhuang
Hua Chen
Rajeev K. Varshney
ResearchOpen Access01 May 2019
Nature Genetics

Volume: 51, P: 865-876
Trajectories of α-fetoprotein and unresectable hepatocellular carcinoma outcomes receiving atezolizumab plus bevacizumab: a secondary analysis of IMbrave150 study

Linbin Lu
Peichan Zheng
Xiong Chen
Research08 Jul 2023
British Journal of Cancer

Volume: 129, P: 620-625
Profiling chromatin states using single-cell itChIP-seq

He and colleagues develop itChIP-seq based on simultaneous cellular indexing and chromatin tagmentation. itChIP-seq is applicable to both low-input and single-cell analyses of chromatin states.

Shanshan Ai
Haiqing Xiong
Aibin He
Research03 Sept 2019
Nature Cell Biology

Volume: 21, P: 1164-1172
Acetylation-dependent SAGA complex dimerization promotes nucleosome acetylation and gene transcription

Biochemical and cellular assays show that the S. cerevisiae SAGA complex undergoes acetylation-dependent dimerization that enables the transcriptional coactivator to cooperatively acetylate nucleosomes, facilitate gene transcription and increase cell survival under stress conditions.

Junhua Huang
Wenjing Dai
Shanshan Li
Research17 Mar 2022
Nature Structural & Molecular Biology

Volume: 29, P: 261-273
Whole-genome resequencing of 445 Lactuca accessions reveals the domestication history of cultivated lettuce

Whole-genome resequencing of 445 Lactuca accessions, including major lettuce crop types and wild relative species, provides a comprehensive map of lettuce genome variations and sheds light on the domestication history of cultivated lettuce.

Tong Wei
Rob van Treuren
Huan Liu
Research12 Apr 2021
Nature Genetics

Volume: 53, P: 752-760
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis

Qianxue Lu
Jin Liu
Lei Wang
ResearchOpen Access28 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Identification and Characterization of Epstein-Barr Virus Genomes in Lung Carcinoma Biopsy Samples by Next-Generation Sequencing Technology

Shanshan Wang
Hongchao Xiong
Zheming Lu
ResearchOpen Access18 May 2016
Scientific Reports

Volume: 6, P: 1-8
New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry

Ningning Liu
Yun Xiong
Wenqing Shui
ResearchOpen Access19 Nov 2015
Scientific Reports

Volume: 5, P: 1-9
Author Correction: Degradation mechanisms of perovskite solar cells under vacuum and one atmosphere of nitrogen

Renjun Guo
Dan Han
Peter Müller-Buschbaum
Amendments and Corrections30 Mar 2022
Nature Energy

Volume: 7, P: 459
Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis

By screening 85 deubiquitylation enzymes, Zhang and colleagues identify OTUD3 as an enzyme that upregulates PTEN levels by deubiquitylation and acts as a tumour suppressor in synergy with another PTEN DUB, USP13.

Lin Yuan
Yanrong Lv
Lingqiang Zhang
Research17 Aug 2015
Nature Cell Biology

Volume: 17, P: 1169-1181
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

Microglia show remarkable regenerative capacity after acute depletion, which had been thought to be derived from de novo progenitors. Peng and colleagues demonstrate that the newly formed microglia are actually solely derived from residual microglia.

Yubin Huang
Zhen Xu
Bo Peng
Research22 Feb 2018
Nature Neuroscience

Volume: 21, P: 530-540
SmedOB1 is Required for Planarian Homeostasis and Regeneration

Shanshan Yin
Yan Huang
Zhou Songyang
ResearchOpen Access22 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
A novel mutation in intron 1 of Wnt1 causes developmental loss of dopaminergic neurons in midbrain and ASD-like behaviors in rats

Yongyi Li
Mingwei Zhu
Ya-Ping Tang
ResearchOpen Access01 Sept 2023
Molecular Psychiatry

Volume: 28, P: 3795-3805
Land subsidence analysis along high-speed railway based on EEMD-Prophet method

Qiu Dongwei
Tong Yuci
Wan Shanshan
ResearchOpen Access06 Jan 2024
Scientific Reports

Volume: 14, P: 1-17
Formation and fluorescent mechanism of red emissive carbon dots from o-phenylenediamine and catechol system

The fluorophore source of red emissive oPD&CAT system CDs is the 5,14-dihydroquinoxalino[2,3-b] phenazine (DHQP), formed in the initial reaction stage. Subsequently, the DHQP was connected with carbon core. The excited electrons of the molecular state can transfer into the energy level of CDs, which leads to UV excitation red emissive intensity decreased.

Pengfei Li
Shanshan Xue
Zaicheng Sun
ResearchOpen Access13 Oct 2022
Light: Science & Applications

Volume: 11, P: 1-11
Decreased plasma ELABELA level as a novel screening indicator for heart failure: a cohort and observational study

Chunju Liu
Jianhua Xiong
Chuanming Xu
ResearchOpen Access17 May 2024
Scientific Reports

Volume: 14, P: 1-15
Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc

Yu Zhong
Liting Yang
Wei Xiong
ResearchOpen Access25 Jun 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-13
BPIFB1 inhibits vasculogenic mimicry via downregulation of GLUT1-mediated H3K27 acetylation in nasopharyngeal carcinoma

Xianjie Jiang
Xiangying Deng
Zhaoyang Zeng
Research01 Nov 2021
Oncogene

Volume: 41, P: 233-245
Plant pathogen resistance is mediated by recruitment of specific rhizosphere fungi

Shanshan Liu
Chengyuan Tao
George A. Kowalchuk
Research10 Apr 2023
The ISME Journal

Volume: 17, P: 931-942
JAZF1 safeguards human endometrial stromal cells survival and decidualization by repressing the transcription of G0S2

JAZF1 regulates human endometrial stromal cells survival and decidualization by restricting the activity of Purβ, which induces the expression of G0S2, a factor that is involved in the mitochondrial apoptotic pathway in recurrent spontaneous abortion.

Yingyu Liang
Siying Lai
Lili Du
ResearchOpen Access27 May 2023
Communications Biology

Volume: 6, P: 1-17
circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma

Le Tang
Wei Xiong
Zhaoyang Zeng
Research29 Oct 2020
Oncogene

Volume: 40, P: 307-321
The E3 ubiquitin ligase, FBXW5, promotes the migration and invasion of gastric cancer through the dysregulation of the Hippo pathway

Yangyang Yao
Zhen Liu
Jun Deng
ResearchOpen Access24 Feb 2022
Cell Death Discovery

Volume: 8, P: 1-12
Hemostatic effect of 3D-printed hip fixators in children with retinoblastoma after intra-arterial chemotherapy: a non-randomized controlled trial

Changjuan Zeng
Yifan Wu
Lili Hou
ResearchOpen Access11 Nov 2024
Scientific Reports

Volume: 14, P: 1-8
Identification and pathogenomic analysis of an Escherichia coli strain producing a novel Shiga toxin 2 subtype

Xiangning Bai
Shanshan Fu
Yanwen Xiong
ResearchOpen Access30 Apr 2018
Scientific Reports

Volume: 8, P: 1-11
Retraction Note: BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer

Weihong Niu
Yanwei Luo
Ming Zhou
Amendments and CorrectionsOpen Access03 Sept 2019
Cell Death & Disease

Volume: 10, P: 1
Picking winners in strategic emerging industries using government subsidies in China: the role of market power

Junguo Shi
Bert M. Sadowski
Sihan Li
ResearchOpen Access10 Jul 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-8
USP49 mediates tumor progression and poor prognosis through a YAP1-dependent feedback loop in gastric cancer

Zhen Liu
Junhe Li
Jun Deng
Research22 Mar 2022
Oncogene

Volume: 41, P: 2555-2570
Trophic interactions between predatory protists and pathogen-suppressive bacteria impact plant health

Sai Guo
Chengyuan Tao
Stefan Geisen
Research23 Apr 2022
The ISME Journal

Volume: 16, P: 1932-1943
LncRNA LINC00472 regulates cell stiffness and inhibits the migration and invasion of lung adenocarcinoma by binding to YBX1

Xiangying Deng
Wei Xiong
Zhaojian Gong
ResearchOpen Access03 Nov 2020
Cell Death & Disease

Volume: 11, P: 1-13
Genetic diversity of the intimin gene (eae) in non-O157 Shiga toxin-producing Escherichia coli strains in China

Xi Yang
Hui Sun
Xiangning Bai
ResearchOpen Access24 Feb 2020
Scientific Reports

Volume: 10, P: 1-9
Temperature-dependent cell death patterns induced by functionalized gold nanoparticle photothermal therapy in melanoma cells

Yujuan Zhang
Xuelin Zhan
Weiping Min
ResearchOpen Access07 Jun 2018
Scientific Reports

Volume: 8, P: 1-9

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