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Showing 1–12 of 12 results

Advanced filters: Author: Sneha Suresh Clear advanced filters

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Efficient Cas9 genome editing in vivo is achieved without viral vectors using chemically modified single-guide RNAs.

Hao Yin
Chun-Qing Song
Daniel G Anderson
Research13 Nov 2017
Nature Biotechnology

Volume: 35, P: 1179-1187
Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag

PE-tag is a genome-wide approach to map the off-target effects of in vitro and in vivo prime editing.

Shun-Qing Liang
Pengpeng Liu
Scot A. Wolfe
Research08 May 2023
Nature Methods

Volume: 20, P: 898-907
Precise therapeutic gene correction by a simple nuclease-induced double-stranded break

Disease-causing microduplications can be corrected by harnessing an endogenous double-stranded break DNA repair pathway.

Sukanya Iyer
Sneha Suresh
Scot A. Wolfe
Research03 Apr 2019
Nature

Volume: 568, P: 561-565
A potent antibiotic-loaded bone-cement implant against staphylococcal bone infections

An antibiotic identified via molecular-docking simulations and screening, and loaded into a bone-cement matrix, performs better than currently used antibiotic-loaded bone cements in the treatment of staphylococcal bone infections in rats.

Sumana Ghosh
Mau Sinha
Shiladitya Sengupta
Research13 Oct 2022
Nature Biomedical Engineering

Volume: 6, P: 1180-1195
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity

Partial substitution of CRISPR RNAs with DNA nucleotides retains CRISPR–Cas9 genome editing activity while enhancing efficiency and specificity within cells, suggesting that DNA–RNA hybrids may be economical reagents for targeted genome editing.

Hao Yin
Chun-Qing Song
Daniel G Anderson
Research29 Jan 2018
Nature Chemical Biology

Volume: 14, P: 311-316
Ocean acidification induces changes in circadian alternative splicing profiles in a coral reef fish

Sneha Suresh
Michael Jarrold
Celia Schunter
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

Cas9-mediated gene editing corrects hereditary tyrosinemia in a mouse model.

Hao Yin
Chun-Qing Song
Daniel G Anderson
Research01 Feb 2016
Nature Biotechnology

Volume: 34, P: 328-333
Cross-talk between tissues is critical for intergenerational acclimation to environmental change in Acanthochromis polyacanthus

Multi-tissue transcriptomic analysis reveals how variability in parental behavioral tolerance and environment shape rapid acclimation to ocean acidification in a coral reef fish.

Sneha Suresh
Megan J. Welch
Celia Schunter
ResearchOpen Access18 Nov 2024
Communications Biology

Volume: 7, P: 1-11
Field validation of deep learning based Point-of-Care device for early detection of oral malignant and potentially malignant disorders

Praveen Birur N.
Bofan Song
Moni A. Kuriakose
ResearchOpen Access22 Aug 2022
Scientific Reports

Volume: 12, P: 1-11
Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer

Voddu Suresh
Rajivgandhi Sundaram
Shantibhusan Senapati
ResearchOpen Access29 Oct 2019
Scientific Reports

Volume: 9, P: 1-16
LIMK2 promotes melanoma tumor growth and metastasis through G3BP1-ESM1 pathway-mediated apoptosis inhibition

Parmanand Malvi
Dhana Sekhar Reddy
Narendra Wajapeyee
Research16 Mar 2023
Oncogene

Volume: 42, P: 1478-1491
Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin

Manoj Garg
Deepika Kanojia
H. Phillip Koeffler
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-11

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Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag

Precise therapeutic gene correction by a simple nuclease-induced double-stranded break

A potent antibiotic-loaded bone-cement implant against staphylococcal bone infections

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity

Ocean acidification induces changes in circadian alternative splicing profiles in a coral reef fish

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

Cross-talk between tissues is critical for intergenerational acclimation to environmental change in Acanthochromis polyacanthus

Field validation of deep learning based Point-of-Care device for early detection of oral malignant and potentially malignant disorders

Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer

LIMK2 promotes melanoma tumor growth and metastasis through G3BP1-ESM1 pathway-mediated apoptosis inhibition

Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin

Search

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