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Showing 101–150 of 170 results

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Author Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
Amendments and CorrectionsOpen Access17 Jun 2025
Nature Genetics

Volume: 57, P: 1788
Publisher Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
Amendments and CorrectionsOpen Access17 Jun 2025
Nature Genetics

Volume: 57, P: 1791
Forearc seismogenesis in a weakly coupled subduction zone influenced by slab mantle fluids

Fluids at the plate interface are sourced from the dehydrating slab mantle beneath the Shumagin Gap in Alaska, and contribute to regional seismic risk by influencing rupture propagation, according to magnetotelluric observations and electrical resistivity modelling.

Darcy Cordell
Samer Naif
Anne Bécel
Research28 Aug 2023
Nature Geoscience

Volume: 16, P: 822-827
CLEARANCE OF HAEMOPHILUS INFLUENZAS TYPE b (Hib) BACTEREMIA REQUIRES C3 FIXATION BUT NOT LYSIS IN THE NONIMMUNE HOST

Gary J Noel
Steven Katz
Paul J Edelson
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 331
Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field

Sui Seng Tee
Valentina DiGialleonardo
Kayvan R. Keshari
ResearchOpen Access06 Sept 2016
Scientific Reports

Volume: 6, P: 1-6
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury

Acetaminophen-induced liver injury is one of the most common causes of liver failure and has to be treated within hours of the overdose. Here Barbier-Torres et al. show that targeting MCJ, a mitochondrial negative regulator, even 24 h after the overdose protects liver from acetaminophen-induced damage.

Lucía Barbier-Torres
Paula Iruzubieta
María Luz Martínez-Chantar
ResearchOpen Access12 Dec 2017
Nature Communications

Volume: 8, P: 1-11
One-way membrane trafficking of SOS in receptor-triggered Ras activation

Analyses in supported lipid bilayers and in cells shed light on the roles of multiple SOS-membrane interactions in SOS's membrane recruitment and association, processive activation of Ras and signal attenuation.

Sune M Christensen
Hsiung-Lin Tu
Jay T Groves
Research08 Aug 2016
Nature Structural & Molecular Biology

Volume: 23, P: 838-846
Digital health technologies in the accelerating medicines Partnership® Schizophrenia Program

Johanna T. W. Wigman
Ann Ee Ching
John Torous
ResearchOpen Access03 Jun 2025
Schizophrenia

Volume: 11, P: 1-10
TMEM175, SCARB2 and CTSB associations with Parkinson’s disease risk across populations

Wenhua Sun
Claudia Schulte
Masharip Atadzhanov
ResearchOpen Access02 Dec 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability

Regina H. Reynolds
Juan Botía
Mina Ryten
ResearchOpen Access17 Apr 2019
npj Parkinson's Disease

Volume: 5, P: 1-14
Author Correction: Global diversity and biogeography of bacterial communities in wastewater treatment plants

Linwei Wu
Daliang Ning
Jizhong Zhou
Amendments and Corrections14 Nov 2019
Nature Microbiology

Volume: 4, P: 2579
Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

Jeffrey A. M. Coull
Dominic Boudreau
Yves De Koninck
Research21 Aug 2003
Nature

Volume: 424, P: 938-942
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice

Milagros Balbín
Antonio Fueyo
Carlos López-Otín
Research28 Sept 2003
Nature Genetics

Volume: 35, P: 252-257
Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege

Alexander W. Charney
Nicole W. Simons
Miriam Merad
Amendments and Corrections21 Aug 2020
Nature Medicine

Volume: 26, P: 1493
Perivascular instruction of cell genesis and fate in the adult brain

Steven A Goldman
Zhuoxun Chen
Reviews26 Oct 2011
Nature Neuroscience

Volume: 14, P: 1382-1389
Evolution of genes and genomes on the Drosophila phylogeny

An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

Andrew G. Clark
Michael B. Eisen
Iain MacCallum
Research08 Nov 2007
Nature

Volume: 450, P: 203-218
Sampling the host response to SARS-CoV-2 in hospitals under siege

Alexander W. Charney
Nicole W. Simons
Miriam Merad
Correspondence27 Jul 2020
Nature Medicine

Volume: 26, P: 1157-1158
Fluoxetine-Induced Sleep Disturbance in Depressed Patients

Cynthia M Dorsey
Scott E Lukas
Steven L Cunningham
Research01 Jun 1996
Neuropsychopharmacology

Volume: 14, P: 437-442
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2

Roan et al. use Olink and single‐cell RNA sequencing (scRNA-seq) to show a dysregulated crosstalk between the cellular and humoral immune responses in individuals with long COVID 8 months postinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Kailin Yin
Michael J. Peluso
Nadia R. Roan
ResearchOpen Access11 Jan 2024
Nature Immunology

Volume: 25, P: 218-225
Averting biodiversity collapse in tropical forest protected areas

Analysis of changes in functional groups of species and potential drivers of environmental change for protected areas across the world’s major tropical regions reveals large variation between reserves that have been effective and those experiencing an erosion of biodiversity, and shows that environmental changes immediately outside reserves are nearly as important as those inside in determining their ecological fate.

William F. Laurance
D. Carolina Useche
Franky Zamzani
Research25 Jul 2012
Nature

Volume: 489, P: 290-294
Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Isidro Cortés-Ciriano
Jake June-Koo Lee
Peter J. Park
Amendments and Corrections13 May 2020
Nature Genetics

Volume: 55, P: 893
Modulation of the expression of Bcl-2 and related proteins in human leukemia cells by protein kinase C activators: relationship to effects on 1-[β-D-arabinofuranosyl]cytosine-induced apoptosis

Tina M Bartimole
Julie A Vrana
Steven Grant
Research01 May 1997
Cell Death & Differentiation

Volume: 4, P: 294-303
Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores

Paula Saffie-Awad
Spencer M. Grant
Sara Bandres-Ciga
ResearchOpen Access03 Jul 2025
npj Parkinson's Disease

Volume: 11, P: 1-13
Perceptions of science, science communication, and climate change attitudes in 68 countries – the TISP dataset

Niels G. Mede
Viktoria Cologna
Rolf A. Zwaan
ResearchOpen Access20 Jan 2025
Scientific Data

Volume: 12, P: 1-27
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra
Rainer Malik
Stephanie Debette
Amendments and CorrectionsOpen Access14 Nov 2022
Nature

Volume: 612, P: E7
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs have unique gene features, and a number display evidence for cancer-driving functions that are conserved from humans to mice.

Joana Carlevaro-Fita
Andrés Lanzós
Christian von Mering
ResearchOpen Access05 Feb 2020
Communications Biology

Volume: 3, P: 1-16
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Julie Williams, Michael Owen and colleagues report staged follow-up and meta-analyses of genome-wide association studies for Alzheimer's disease from the GERAD+ consortium. They identify common variants at ABCA7 and MS4A6A/MS4A4E associated with Alzheimer's disease and support for several additional susceptibility loci.

Paul Hollingworth
Denise Harold
Julie Williams
Research03 Apr 2011
Nature Genetics

Volume: 43, P: 429-435
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Philippe Amouyel, Julie Williams, Gerard Schellenberg, Sudha Seshadri and colleagues report a meta-analysis of genome-wide association studies for late-onset Alzheimer's disease in 17,008 cases and 37,154 controls with replication in an additional 8,572 cases and 11,312 controls. They identify 11 loci newly associated with Alzheimer's disease.

Jean-Charles Lambert
Carla A Ibrahim-Verbaas
Philippe Amouyel
Research27 Oct 2013
Nature Genetics

Volume: 45, P: 1452-1458
rsc: a novel oncogene with structural and functional homology with the gene family of exchange factors for Ral

David R D'Adamo
Steven Novick
Angel Pellicer
Research20 Mar 1997
Oncogene

Volume: 14, P: 1295-1305
A novel Alzheimer disease locus located near the gene encoding tau protein

G Jun
C A Ibrahim-Verbaas
L A Farrer
Research17 Mar 2015
Molecular Psychiatry

Volume: 21, P: 108-117
The breakup of a long-period comet is not a likely match to the Chicxulub impactor

Steven J. Desch
Alan P. Jackson
Ariel D. Anbar
ResearchOpen Access21 Jun 2022
Scientific Reports

Volume: 12, P: 1-4
Microbial production of recalcitrant dissolved organic matter: long-term carbon storage in the global ocean

Recalcitrant dissolved organic matter is now known to be a key element in the global carbon cycle. Here, Nianzhi Jiao and colleagues set out the role of ocean-dwelling microorganisms in the generation of this pool of long-lived carbon, using a new concept they call the microbial carbon pump.

Nianzhi Jiao
Gerhard J. Herndl
Farooq Azam
Reviews05 Jul 2010
Nature Reviews Microbiology

Volume: 8, P: 593-599
Single-molecule evaluation of fluorescent protein photoactivation efficiency using an in vivo nanotemplate

A system using the human glycine receptor expressed in Xenopus oocytes allows characterization of the photoactivation efficiency of photoactivatable and photoconvertible fluorescent proteins at the single-molecule level, providing crucial data for using these probes for quantitative super-resolution microscopy.

Nela Durisic
Lara Laparra-Cuervo
Melike Lakadamyali
Research05 Jan 2014
Nature Methods

Volume: 11, P: 156-162
X‐chromosome-wide association study for Alzheimer’s disease

Julie Le Borgne
Lissette Gomez
Céline Bellenguez
ResearchOpen Access04 Dec 2024
Molecular Psychiatry

Volume: 30, P: 2335-2346
Spatial limitations in averaging social cues

Joseph Florey
Colin W. G. Clifford
Isabelle Mareschal
ResearchOpen Access30 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
Clinicopathological analysis of basal cell carcinoma of the anal region and its distinction from basaloid squamous cell carcinoma

Deepa T Patil
John R Goldblum
Steven D Billings
Research19 Apr 2013
Modern Pathology

Volume: 26, P: 1382-1389
Herbimycin A accelerates the induction of apoptosis following etoposide treatment or γ-irradiation of bcr/abl-positive leukaemia cells

Fiona A Riordan
Christopher A Bravery
R Gitendra Wickremasinghe
Research01 Apr 1998
Oncogene

Volume: 16, P: 1533-1542
Interplay between materials and microfluidics

In this Review, the interplay between materials and microfluidics is examined, with the discussion focused on how recent advances in materials fabrication have expanded the frontiers of microfluidic platforms and how the new microfluidic capabilities are, in turn, furthering materials design.

Xu Hou
Yu Shrike Zhang
Ali Khademhosseini
Reviews20 Apr 2017
Nature Reviews Materials

Volume: 2, P: 1-15
Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics

López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation. They show that pathological and pharmacological low-level states of consciousness display disrupted synchronization patterns, higher constraint to the anatomy and a loss of heterogeneity and stability in the structural hubs compared to conscious states.

Ane López-González
Rajanikant Panda
Gustavo Deco
ResearchOpen Access06 Sept 2021
Communications Biology

Volume: 4, P: 1-15
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Mev Dominguez-Valentin
Julian R. Sampson
Pål Møller
ResearchOpen Access24 Jul 2019
Genetics in Medicine

Volume: 22, P: 15-25
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Mev Dominguez-Valentin
Emma J. Crosbie
Pål Møller
ResearchOpen Access01 Dec 2020
Genetics in Medicine

Volume: 23, P: 705-712
AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach
Denzil Bernard
Abraham Heifets
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-16
Paradoxical Anxiogenic Response of Juvenile Mice to Fluoxetine

Ji-eun Oh
Bojana Zupan
Miklos Toth
Research13 May 2009
Neuropsychopharmacology

Volume: 34, P: 2197-2207
Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)

Lara M. Lange
Micol Avenali
Masharip Atadzhanov
Amendments and CorrectionsOpen Access13 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-3
A quantum chemical interaction energy dataset for accurately modeling protein-ligand interactions

Steven A. Spronk
Zachary L. Glick
Daniel L. Cheney
ResearchOpen Access12 Sept 2023
Scientific Data

Volume: 10, P: 1-14
The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

Lara M. Lange
Kristin Levine
Masharip Atadzhanov
ResearchOpen Access25 Mar 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study

Sidhant Chopra
Alex Fornito
Patrick McGorry
ResearchOpen Access26 Feb 2021
Neuropsychopharmacology

Volume: 46, P: 1494-1501
Cytokine signatures of end organ injury in COVID-19

Luis G. Gómez-Escobar
Katherine L. Hoffman
Edward J. Schenck
ResearchOpen Access15 Jun 2021
Scientific Reports

Volume: 11, P: 1-15

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