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Showing 251–300 of 358 results

Advanced filters: Author: Taylor Robinson Clear advanced filters

The promise of metabolic phenotyping in gastroenterology and hepatology

Disease risk and treatment response is determined by an individual's complex history of genetic and environmental interactions. Personalized health care therefore requires an in-depth understanding of patient biology that can now be measured using '-omics' technologies. In this Review, different metabolic profiling methods and applications are described that might introduce a new dimension in personalized patient care in gastroenterology and hepatology.

Elaine Holmes
Anisha Wijeyesekera
Jeremy K. Nicholson
Reviews21 Jul 2015
Nature Reviews Gastroenterology & Hepatology

Volume: 12, P: 458-471
Generational effects of culture and digital media in former Soviet Republics

Benjamin D. Horne
Natalie M. Rice
R. Alexander Bentley
ResearchOpen Access19 Apr 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-11
Mendelian randomisation study of smoking exposure in relation to breast cancer risk

Hanla A. Park
Sonja Neumeyer
Jenny Chang-Claude
ResearchOpen Access02 Aug 2021
British Journal of Cancer

Volume: 125, P: 1135-1145
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

Nichola Johnson
Sarah Maguire
Olivia Fletcher
ResearchOpen Access26 Jan 2021
British Journal of Cancer

Volume: 124, P: 842-854
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Amendments and Corrections17 Jul 2020
Nature

Volume: 584, P: E2
Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx

Alexander M. Frankell
Michelle Dietzen
Charles Swanton
Amendments and CorrectionsOpen Access04 Jul 2024
Nature

Volume: 631, P: E15
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Advances in next generation sequencing have made it possible to precisely characterize the coding mutations that occur during the development and progression of individual cancers. Here, this technique is used to sequence the genomes and transcriptomes of an oestrogen-receptor-α-positive metastatic lobular breast cancer; significant evolution is found to occur with disease progression.

Sohrab P. Shah
Ryan D. Morin
Samuel Aparicio
ResearchOpen Access08 Oct 2009
Nature

Volume: 461, P: 809-813
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer
Garrett Hellenthal
Alastair Compston
Research10 Aug 2011
Nature

Volume: 476, P: 214-219
Precise interpolar phasing of abrupt climate change during the last ice age

A new ice core from West Antarctica shows that, during the last ice age, abrupt Northern Hemisphere climate variations were followed two centuries later by a response in Antarctica, suggesting an oceanic propagation of the climate signal to the Southern Hemisphere high latitudes.

Christo Buizert
Betty Adrian
Thomas E. Woodruff
Research08 Apr 2015
Nature

Volume: 520, P: 661-665
The Genotype-Tissue Expression (GTEx) project

John Lonsdale
Jeffrey Thomas
Helen F Moore
Comments & OpinionOpen Access29 May 2013
Nature Genetics

Volume: 45, P: 580-585
A survey of chairpersons of departments of medicine about the current and future roles of clinical genetics in internal medicine

Matthew R G Taylor
Research01 Jul 2003
Genetics in Medicine

Volume: 5, P: 328-331
TOWARD THE ELIMINATION OF VARICELLA IN CHILDREN WITH LEUKEMIA

Jean Taylor-Wiedeman
Philip A Brunell
Ziad M Shehab
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 250
Challenges to curing primary brain tumours

Brain cancer encompasses a diverse range of complex malignancies, many of which are associated with a poor prognosis and require more effective treatments. In this Position Paper, an international panel of clinicians and laboratory-based scientists convened by Cancer Research UK identify and discuss seven challenges that must be overcome if we are to cure all patients with a brain tumour.

Kenneth Aldape
Kevin M. Brindle
Richard J. Gilbertson
ReviewsOpen Access07 Feb 2019
Nature Reviews Clinical Oncology

Volume: 16, P: 509-520
Classification of pain following spinal cord injury

P J Siddall
D A Taylor
M J Cousins
Research01 Feb 1997
Spinal Cord

Volume: 35, P: 69-75
Mapping of population disparities in the cholangiocarcinoma urinary metabolome

Munirah Alsaleh
Zoe Leftley
Simon D. Taylor-Robinson
ResearchOpen Access28 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)

Thomas Starkey
Maria C. Ionescu
Lennard Y. W. Lee
ResearchOpen Access25 Jul 2023
Scientific Reports

Volume: 13, P: 1-8
Heterogeneous distribution of water in the Moon

The discovery of water in lunar samples in 2008 challenged the notion that the Moon's interior had lost all its volatiles. Since then, analyses of the water concentrations and isotopic compositions in lunar samples taken together suggest that the Moon is heterogeneously wet, which may lend clues to its origin.

Katharine L. Robinson
G. Jeffrey Taylor
Reviews25 May 2014
Nature Geoscience

Volume: 7, P: 401-408
Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

Frank Dieterle
Frank Sistare
William Mattes
Reviews10 May 2010
Nature Biotechnology

Volume: 28, P: 455-462
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Brian J. Willett
Joe Grove
Emma C. Thomson
Amendments and CorrectionsOpen Access16 Sept 2022
Nature Microbiology

Volume: 7, P: 1709
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1

Bianca Jupp
Silvia Pitzoi
Jeffrey W. Dalley
ResearchOpen Access21 Apr 2020
Scientific Reports

Volume: 10, P: 1-13
Disruption prediction with artificial intelligence techniques in tokamak plasmas

Tokamak plasmas are prone to sudden collapses that terminate the nuclear fusion reactions. This perspective discusses the prediction of these so-called disruptions with artificial intelligence techniques.

J. Vega
A. Murari
I. Zychor
Reviews06 Jun 2022
Nature Physics

Volume: 18, P: 741-750
Hepatic encephalopathy

Hepatic encephalopathy is a neuropsychiatric syndrome that occurs in patients with liver disease. This Primer discusses the epidemiology, pathophysiology, diagnosis and treatment of hepatic encephalopathy, and discusses how this disorder affects the quality of life of patients.

Dieter Häussinger
Radha K. Dhiman
Hendrik Vilstrup
Reviews23 Jun 2022
Nature Reviews Disease Primers

Volume: 8, P: 1-22
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

An in vivo transposon screen in a pancreatic cancer model identifies frequent inactivation of Usp9x; deletion of Usp9x cooperates with Kras^G12D to accelerate rapidly pancreatic tumorigenesis in mice, validating their genetic interaction.

Pedro A. Pérez-Mancera
Alistair G. Rust
David A. Tuveson
Research29 Apr 2012
Nature

Volume: 486, P: 266-270
Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

Takele et al. conduct a systematic review and meta-analysis of the effects of intervention characteristics on preventing gestational diabetes. Group or healthcare facility-based physical activity interventions are found to be more effective in preventing gestational diabetes than community-based interventions.

Wubet Worku Takele
Kimberly K. Vesco
Siew Lim
ResearchOpen Access20 Apr 2024
Communications Medicine

Volume: 4, P: 1-15
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

Thomas W. Winkler
Humaira Rasheed
Iris M. Heid
ResearchOpen Access13 Jun 2022
Communications Biology

Volume: 5, P: 1-20
Publisher Correction: Shared heritability and functional enrichment across six solid cancers

Xia Jiang
Hilary K. Finucane
Sara Lindström
Amendments and CorrectionsOpen Access23 Sept 2019
Nature Communications

Volume: 10, P: 1-8
Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

Anna Murphy
Liam J Nestor
Rebecca Elliott
ResearchOpen Access02 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1049-1057
Child abuse and the eye

David Taylor
R Bonshek
J D H Young
Reviews01 Jan 1999
Eye

Volume: 13, P: 3-10
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Medulloblastoma

This Primer by Pfister and colleagues reviews the molecular genetics, diagnosis and management of medulloblastoma and touches upon the quality of life of patients and future outlooks.

Paul A. Northcott
Giles W. Robinson
Stefan M. Pfister
Reviews14 Feb 2019
Nature Reviews Disease Primers

Volume: 5, P: 1-20
Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT

Paul D. Taylor
Haotian Gu
Lynne Greenwood
ResearchOpen Access12 Oct 2022
International Journal of Obesity

Volume: 46, P: 2145-2155
Participant characteristics in the prevention of gestational diabetes as evidence for precision medicine: a systematic review and meta-analysis

Lim et al. perform a systematic review and meta-analysis to identify participant characteristics associated with response to gestational diabetes prevention. Characteristics such as BMI, polycystic ovary syndrome and being in the preconception phase could determine responses to certain preventive interventions.

Siew Lim
Wubet Worku Takele
Jami Josefson
ResearchOpen Access05 Oct 2023
Communications Medicine

Volume: 3, P: 1-11
Culture and awareness of occupational health risks amongst UK firefighters

Taylor A. M. Wolffe
Louis Turrell
Anna A. Stec
ResearchOpen Access10 Jan 2023
Scientific Reports

Volume: 13, P: 1-12
Contamination of UK firefighters personal protective equipment and workplaces

Taylor A. M. Wolffe
Anna Clinton
Anna A. Stec
ResearchOpen Access10 Jan 2023
Scientific Reports

Volume: 13, P: 1-12
Mental health of UK firefighters

Taylor A. M. Wolffe
Andrew Robinson
Anna A. Stec
ResearchOpen Access10 Jan 2023
Scientific Reports

Volume: 13, P: 1-12
Cancer incidence amongst UK firefighters

Taylor A. M. Wolffe
Andrew Robinson
Anna A. Stec
ResearchOpen Access10 Jan 2023
Scientific Reports

Volume: 12, P: 1-13
Effects of Suvorexant, a Dual Orexin/Hypocretin Receptor Antagonist, on Impulsive Behavior Associated with Cocaine

Taylor A Gentile
Steven J Simmons
John W Muschamp
Research25 Jul 2017
Neuropsychopharmacology

Volume: 43, P: 1001-1009
Prenatal Nicotine Exposure Impairs Executive Control Signals in Medial Prefrontal Cortex

Daniel W Bryden
Amanda C Burton
Matthew R Roesch
Research20 Jul 2015
Neuropsychopharmacology

Volume: 41, P: 716-725
Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis

David A. Sheridan
Isaac Thom Shawa
Simon D. Taylor-Robinson
ResearchOpen Access01 Apr 2022
Scientific Reports

Volume: 12, P: 1-11
Cytokine changes in cerebrospinal fluid and plasma after emergency orthopaedic surgery

Michael Fertleman
Christopher Pereira
Simon D. Taylor-Robinson
ResearchOpen Access09 Feb 2022
Scientific Reports

Volume: 12, P: 1-10
Precision treatment of beta-cell monogenic diabetes: a systematic review

Naylor et al. systematically review the efficacy of treatments for beta-cell monogenic diabetes. Limited evidence from the mostly non-randomized, small studies supports no treatment in glucokinase-related hyperglycemia and sulfonylureas for HNF1A-diabetes; further evidence is needed on the optimum treatments in these and other monogenic subtypes.

Rochelle N. Naylor
Kashyap A. Patel
Tiinamaija Tuomi
ResearchOpen Access18 Jul 2024
Communications Medicine

Volume: 4, P: 1-17
Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

Alvis Brazma
Pascal Hingamp
Martin Vingron
Comments & Opinion01 Dec 2001
Nature Genetics

Volume: 29, P: 365-371
In vitro methods to prepare astrocyte and motoneuron cultures for the investigation of potential in vivo interactions

Anna R Taylor
Mac B Robinson
Carol E Milligan
Protocols07 Jun 2007
Nature Protocols

Volume: 2, P: 1499-1507
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial

Amy Goodwin
Emily J. H. Jones
Mark H. Johnson
ResearchOpen Access20 Dec 2021
Translational Psychiatry

Volume: 11, P: 1-9
Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

Alexander Roberts
Lindsay Bentley
Nicholas M. Barnes
ResearchOpen Access17 Feb 2021
Scientific Reports

Volume: 11, P: 1-12
Hand-portable HPLC with broadband spectral detection enables analysis of complex polycyclic aromatic hydrocarbon mixtures

Portable liquid chromatography instruments enable a myriad of applications in field research. Here a handportable system incorporating a broadband absorption detector is used to separate and classify polycyclic aromatic hydrocarbons from environmental water samples based solely on spectral fingerprinting.

Stelios Chatzimichail
Faraz Rahimi
Ali Salehi-Reyhani
ResearchOpen Access16 Feb 2021
Communications Chemistry

Volume: 4, P: 1-14
Dropsonde observations during the Aerosol Cloud meTeorology Interactions oVer the western ATlantic Experiment

Holger Vömel
Armin Sorooshian
Luke D. Ziemba
ResearchOpen Access01 Nov 2023
Scientific Data

Volume: 10, P: 1-14
Dual-probe molecular MRI for the in vivo characterization of atherosclerosis in a mouse model: Simultaneous assessment of plaque inflammation and extracellular-matrix remodeling

Carolin Reimann
Julia Brangsch
Marcus R. Makowski
ResearchOpen Access25 Sept 2019
Scientific Reports

Volume: 9, P: 1-10

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