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Scientific Reports (21)
Acta Pharmacologica Sinica (11)
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Showing 1–50 of 67 results

Advanced filters: Author: Ting-Ting Jiang Clear advanced filters

Atomically precise gold nanocluster boosting selective hydrogenation of nitroarene by H₂ in water

The chemoselective hydrogenation of molecules containing multiple reducible groups using molecular hydrogen presents inherent challenges. Here, the authors synthesize a homoleptic gold nanocluster that demonstrates exceptional catalytic selectivity, activity, and yield for the hydrogenation of 4-nitroacetophenone in water under mild conditions.

Xiao-Xiao Lai
Jianyu Wei
Quan-Ming Wang
ResearchOpen Access23 Aug 2025
Nature Communications

Volume: 16, P: 1-11
Genome-resolved metagenomics reveals microbiome diversity across 48 tick species

Sequencing the genome and microbiome of about 1,500 tick samples from regions across China revealed host–microbe associations in ticks that could have implications for controlling ticks and tick-borne diseases.

Li-Feng Du
Wenyu Shi
Wu-Chun Cao
ResearchOpen Access23 Sept 2025
Nature Microbiology

Volume: 10, P: 2631-2645
Correction: Clinical-mediated discovery of pyroptosis in CD8⁺ T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence

Ying Zhang
Yun Bai
Bin Li
Amendments and CorrectionsOpen Access22 Feb 2024
Cell Death & Disease

Volume: 15, P: 1-2
Proteomic characterization of epithelial ovarian cancer delineates molecular signatures and therapeutic targets in distinct histological subtypes

The molecular phenotypic features of epithelial ovarian cancer (EOC) remain elusive. Here, the authors perform mass spectrometry-based proteomic profiling for 269 EOC patients and reveal molecularly distinct features and potential therapeutic targets among the histological subtypes of EOC.

Ting-Ting Gong
Shuang Guo
Qi-Jun Wu
ResearchOpen Access28 Nov 2023
Nature Communications

Volume: 14, P: 1-15
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease

Yan-Bing Chen
Bo Jiang
Jie Zhang
ResearchOpen Access06 Sept 2025
Molecular Psychiatry

P: 1-13
Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes

Qing Li
Ting-ting Tang
Wei-ping Jia
Research03 Oct 2016
Acta Pharmacologica Sinica

Volume: 38, P: 80-89
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases

Berberine has lipid-lowering effects and other metabolic benefits, but it presents with poor bioavailability. Here the authors conjugate berberine to liver-targeting nanoparticles, and show increased accumulation of berberine in the liver, improved metabolic profiles and reduced atherosclerotic plaques in mice.

Hui-Hui Guo
Chen-Lin Feng
Jian-Dong Jiang
ResearchOpen Access30 Apr 2019
Nature Communications

Volume: 10, P: 1-16
De novo genome assembly depicts the immune genomic characteristics of cattle

The genomic organisation of the cattle genome has been assembled to a limited level of resolution. Here using long range nanopore sequencing the authors present a cattle genome assembly concentrating on characterising the immunogenomic loci, particularly T cell receptor (TR), immunoglobulin (IG) and MHC genes, from one animal.

Ting-Ting Li
Tian Xia
Tao Li
ResearchOpen Access19 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins

SARS-CoV-2-related coronaviruses are identified in Malayan pangolins (Manis javanica); these pangolin-associated coronaviruses belonged to two sub-lineages of SARS-CoV-2-related coronaviruses, including one that exhibits strong similarity in the receptor-binding domain to SARS-CoV-2.

Tommy Tsan-Yuk Lam
Na Jia
Wu-Chun Cao
Research26 Mar 2020
Nature

Volume: 583, P: 282-285
Experimental study on the energy dissipation mechanism of bolted rock under dynamic loading

Peng-qi Qiu
Wen-wei Wang
Xiaoyong Yang
ResearchOpen Access17 May 2025
Scientific Reports

Volume: 15, P: 1-14
Astrocytic ALKBH5 in stress response contributes to depressive-like behaviors in mice

The regulatory mechanism and function of astrocytic epigenetic effects on depression remain to be explored. Here, the authors show astrocytic ALKBH5 contributes to depressive-like behaviors via the m6A RNA methylation of GLT-1.

Fang Guo
Jun Fan
Xiong Cao
ResearchOpen Access21 May 2024
Nature Communications

Volume: 15, P: 1-19
YY1/HIF-1α/mROS positive-feedback loop exacerbates glomerular mesangial cell proliferation in mouse early diabetic kidney disease

Ting-ting Yang
Yu-ting Shao
Qian Lu
Research04 Mar 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1974-1989
Correction: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Ke-Wu Zeng
Jing-Kang Wang
Pengfei Tu
Amendments and CorrectionsOpen Access04 Apr 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-2
Association of alpha-fetoprotein and metastasis for small hepatocellular carcinoma: A propensity-matched analysis

Yu-Qi Wang
An-Jiang Wang
Si-Hai Chen
ResearchOpen Access20 Sept 2022
Scientific Reports

Volume: 12, P: 1-9
The study of automatic machine learning base on radiomics of non-focus area in the first chest CT of different clinical types of COVID-19 pneumonia

Hui-Bin Tan
Fei Xiong
Bi-Wen Peng
ResearchOpen Access03 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
Adverse drug events in Chinese pediatric inpatients and associated risk factors: a retrospective review using the Global Trigger Tool

Huan-huan Ji
Lin Song
Yun-tao Jia
ResearchOpen Access07 Feb 2018
Scientific Reports

Volume: 8, P: 1-7
Excessive antibiotics use increased in-hospital mortality in intracerebral hemorrhage patients with stroke-associated infection

Fei Wang
Yinghua Wang
Xiao Wu
ResearchOpen Access06 Feb 2020
Scientific Reports

Volume: 10, P: 1-8
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

Long Yu and colleagues report a genome-wide association study for hepatitis B virus–related hepatocellular carcinoma (HBV-HCC). They report that genetic variants in STAT4 and HLA-DQ genes confer risk of HBV-HCC.

De-Ke Jiang
Jielin Sun
Long Yu
Research16 Dec 2012
Nature Genetics

Volume: 45, P: 72-75
Neuraminidase 1 promotes renal fibrosis development in male mice

The influenza virus neuraminidase has been well documented, yet the functions of mammalian neuraminidases remain less explored. Here, the authors show that neuraminidase 1 promotes renal fibrosis development by interacting with ALK5 to activate SMAD2/3.

Qian-Qian Chen
Kang Liu
Lei Zhang
ResearchOpen Access27 Mar 2023
Nature Communications

Volume: 14, P: 1-20
Anodic Electrogenerated Chemiluminescence of Ru(bpy)₃²⁺ with CdSe Quantum Dots as Coreactant and Its Application in Quantitative Detection of DNA

Yong-Ping Dong
Ting-Ting Gao
Jun-Jie Zhu
ResearchOpen Access16 Oct 2015
Scientific Reports

Volume: 5, P: 1-10
Decreasing prevalence and time trend of gastroschisis in 14 cities of Liaoning Province: 2006–2015

Na Li
Yan-Ling Chen
Yan-Hong Huang
ResearchOpen Access14 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Evaluating the time trends in prevalence of exomphalos in 14 cities of Liaoning province, 2006 to 2015

Ting-Ting Gong
Qi-Jun Wu
Yan-Hong Huang
ResearchOpen Access08 Sept 2016
Scientific Reports

Volume: 6, P: 1-8
Screening and identification of lncRNAs as potential biomarkers for pulmonary tuberculosis

Zhong-liang Chen
Li-Liang Wei
Ji-Cheng Li
ResearchOpen Access01 Dec 2017
Scientific Reports

Volume: 7, P: 1-10
TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling

BTRC can activate NF-κB signaling through the ubiquitination and degradation of IκB-α. Here the authors show that TSPAN15 promotes metastasis of oesophageal squamous cell cancer by enhancing BTRC induced degradation of IκB-α and subsequent activation of NF-κB.

Baozhu Zhang
Zhao Zhang
Ying-Hui Zhu
ResearchOpen Access12 Apr 2018
Nature Communications

Volume: 9, P: 1-12
Correction: H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance

Fei Peng
Ting-Ting Li
Quentin Liu
Amendments and CorrectionsOpen Access27 Aug 2024
Cell Death & Disease

Volume: 15, P: 1
Clinical characteristics and disease-specific prognostic nomogram for primary gliosarcoma: a SEER population-based analysis

Song-Shan Feng
Huang-bao Li
Quan Cheng
ResearchOpen Access24 Jul 2019
Scientific Reports

Volume: 9, P: 1-9
Blockage of UCHL1 activity attenuates cardiac remodeling in spontaneously hypertensive rats

Xiao Han
Yun-Long Zhang
Hui-Hua Li
Research15 Jun 2020
Hypertension Research

Volume: 43, P: 1089-1098
Activation of MST1 protects filtration barrier integrity of diabetic kidney disease in mice through restoring the tight junctions of glomerular endothelial cells

Ting-ting Yang
Ying Liu
Xiao-xing Yin
Research06 Dec 2024
Acta Pharmacologica Sinica

Volume: 46, P: 1345-1360
IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population

Ling-Feng Zha
Shao-Fang Nie
Xiang Cheng
ResearchOpen Access18 Apr 2018
Scientific Reports

Volume: 8, P: 1-8
Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis

Xue-Jun Zhang, Jun Wang and colleagues identify mutations in MVK in disseminated superficial actinic porokeratosis, a disorder characterized by defects in epidermal keratinization. MVK encodes mevalonate kinase, an enzyme involved in the biosynthesis of cholesterol and isoprenoids.

Sheng-Quan Zhang
Tao Jiang
Xue-Jun Zhang
Research16 Sept 2012
Nature Genetics

Volume: 44, P: 1156-1160
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation

SH3RF2 suppresses RBPMS stability to promote AP-1 transactivation, and thereby contributes to cisplatin resistance in ovarian cancer cells

Ting-Ting Gong
Fang-Hua Liu
Qi-Jun Wu
ResearchOpen Access09 Jan 2024
Communications Biology

Volume: 7, P: 1-15
Correction: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Ke-Wu Zeng
Jing-Kang Wang
Pengfei Tu
Amendments and CorrectionsOpen Access12 Mar 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-2
Simplifying multidimensional fermentation dataset analysis and visualization: One step closer to capturing high-quality mutant strains

Xiang Zhou
Dan Xu
Ting-Ting Jiang
ResearchOpen Access03 Jan 2017
Scientific Reports

Volume: 7, P: 1-12
Chromosome-level genome assembly and annotation of Flueggea virosa (Phyllanthaceae)

Bao-Zheng Chen
Zi-Jiang Yang
Wen-Bin Yu
ResearchOpen Access13 Aug 2024
Scientific Data

Volume: 11, P: 1-11
Dietary fat intake and endometrial cancer risk: dose-response meta-analysis of epidemiological studies

Luo Jiang
Rui Hou
Qi-Jun Wu
ResearchOpen Access16 Nov 2015
Scientific Reports

Volume: 5, P: 1-11
Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway

Hong-Ying Li
Ting-Ting Wei
Lingpeng Zhu
ResearchOpen Access18 Nov 2023
Cell Death Discovery

Volume: 9, P: 1-15
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice

Ting-ting Zhou
Tong Zhao
Xu Shen
Research04 Mar 2019
Acta Pharmacologica Sinica

Volume: 40, P: 1193-1204
The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations

Ting-ting Liu
Teng Yang
Hua-liang Jiang
Research22 Feb 2019
Acta Pharmacologica Sinica

Volume: 40, P: 850-858
Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression

Yi-pin Lv
Liu-sheng Peng
Yuan Zhuang
ResearchOpen Access10 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-12
Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Ke-Wu Zeng
Jing-Kang Wang
Pengfei Tu
ResearchOpen Access19 Feb 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-13
CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis

Lin Du
Xiu-guo Han
Ting-ting Tang
ResearchOpen Access18 Jun 2018
Cell Death & Disease

Volume: 9, P: 1-11
Retraction Note: Inhibition of microRNA-214 promotes epithelial–mesenchymal transition process and induces interstitial cystitis in postmenopausal women by upregulating Mfn2

Jian-Wei Lv
Wei Wen
Wei Xue
Amendments and CorrectionsOpen Access14 Jun 2022
Experimental & Molecular Medicine

Volume: 54, P: 861
Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling

Shuang Yang
Hou-wei Li
Xue Liu
Research19 Sept 2023
Acta Pharmacologica Sinica

Volume: 45, P: 98-111
Clinical-mediated discovery of pyroptosis in CD8⁺ T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence

Ying Zhang
Yun Bai
Bin Li
ResearchOpen Access24 Aug 2023
Cell Death & Disease

Volume: 14, P: 1-14
Genome-wide screening identifies oncofetal lncRNA Ptn-dt promoting the proliferation of hepatocellular carcinoma cells by regulating the Ptn receptor

Jin-Feng Huang
Hong-Yue Jiang
Fang Wang
Research14 Jan 2019
Oncogene

Volume: 38, P: 3428-3445
HN1L-mediated transcriptional axis AP-2γ/METTL13/TCF3-ZEB1 drives tumor growth and metastasis in hepatocellular carcinoma

Lei Li
Yin-Li Zheng
Xin-Yuan Guan
Research18 Feb 2019
Cell Death & Differentiation

Volume: 26, P: 2268-2283
Copper-catalyzed alkyne oxidation/Büchner-type ring-expansion to access benzo[6,7]azepino[2,3-b]quinolines and pyridine-based diones

Organic molecules containing seven-membered rings are important structural motifs for drug candidates, but the construction of seven-membered rings can be challenging through traditional cyclization pathways. Here, the authors report a copper-catalyzed alkyne oxidation and Büchner-type ring-expansion to generate benzo[6,7]azepino[2,3-b]quinolines and pyridine-based diones.

Xiao-Lei Jiang
Qing Liu
Wen-Bo Shen
ResearchOpen Access20 Feb 2023
Communications Chemistry

Volume: 6, P: 1-12
Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson’s disease mouse model through activating GHS-R1a/D₂R heterodimers

Ting-ting Tang
Ming-xia Bi
Hong Jiang
ResearchOpen Access10 Mar 2023
Acta Pharmacologica Sinica

Volume: 44, P: 1564-1575
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs

Xiao-kang Zhao
Meng-meng Zhu
Yuan-li Chen
Research30 Mar 2023
Acta Pharmacologica Sinica

Volume: 44, P: 1625-1636
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies

Kai-long Jiang
Le-xian Tong
Jia Li
Research29 Mar 2021
Acta Pharmacologica Sinica

Volume: 43, P: 220-228

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