Nature Search

Is adenosine the mediator of opiate action on neuronal firing rate?

Trevor W. Stone
Martin N. Perkins
Research01 Sept 1979
Nature

Volume: 281, P: 227-228
A Fossil Human Mandible from a Levalloiso–Mousterian Horizon in Cyrenaica

C. B. M. McBURNEY
J. C. TREVOR
L. H. WELLS
Research14 Nov 1953
Nature

Volume: 172, P: 889-891
Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus

Martin N. Perkins
Nancy J. Rothwell
Trevor W. Stone
Research29 Jan 1981
Nature

Volume: 289, P: 401-402
Hominin presence in Eurasia by at least 1.95 million years ago

When hominins dispersed into Eurasia is unclear. Here, the authors present multiple cut-marked bones from Grăunceanu, Romania dated to at least 1.95 million years ago and suggest hominins would have lived in a temperate and seasonal environment.

Sabrina C. Curran
Virgil Drăgușin
Claire E. Terhune
ResearchOpen Access20 Jan 2025
Nature Communications

Volume: 16, P: 1-11
Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

Bruno Amati
Stephen Dalton
Hartmut Land
Research01 Oct 1992
Nature

Volume: 359, P: 423-426
Grandmaster level in StarCraft II using multi-agent reinforcement learning

AlphaStar uses a multi-agent reinforcement learning algorithm and has reached Grandmaster level, ranking among the top 0.2% of human players for the real-time strategy game StarCraft II.

Oriol Vinyals
Igor Babuschkin
David Silver
Research30 Oct 2019
Nature

Volume: 575, P: 350-354
Fine-scale patterns of SARS-CoV-2 spread from identical pathogen sequences

The analysis of pairs of identical SARS-CoV-2 genome sequences enables characterization of transmission patterns between geographies and age groups.

Cécile Tran-Kiem
Miguel I. Paredes
Trevor Bedford
ResearchOpen Access05 Mar 2025
Nature

Volume: 640, P: 176-185
Deformation and bursting of elastic capsules impacting a rigid wall

Experiments on the deformation and bursting of elastic capsules impacting rigid walls are reported, revealing an analogy to the impact of liquid drops. The developed model for macroscopic objects could potentially be expanded to microscopic scales.

Etienne Jambon-Puillet
Trevor J. Jones
P.-T. Brun
Research16 Mar 2020
Nature Physics

Volume: 16, P: 585-589
Cultural innovation and megafauna interaction in the early settlement of arid Australia

Warratyi rock shelter shows evidence of human occupation approximately 50,000 years ago, development of tool use and cultural innovation, and interaction with now-extinct megafauna in arid Australia.

Giles Hamm
Peter Mitchell
Duncan Johnston
Research02 Nov 2016
Nature

Volume: 539, P: 280-283
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Impacts of human mobility on the citywide transmission dynamics of 18 respiratory viruses in pre- and post-COVID-19 pandemic years

Population mobility is associated with SARS-CoV-2 transmission but its impacts on other respiratory viruses are not well understood. Here, the authors investigate associations between mobile phone-derived mobility metrics and the dynamics of 18 respiratory viruses in Seattle, Washington from 2018 to 2022.

Amanda C. Perofsky
Chelsea L. Hansen
Cécile Viboud
ResearchOpen Access16 May 2024
Nature Communications

Volume: 15, P: 1-17
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota

Human infections with Campylobacter fetus are often assumed to be derived from livestock. Here, Iraola et al. provide evidence that healthy humans may act as carriers and dispersers, and C. fetus may have originated in humans as an intestinal pathobiont and then adapted as a livestock pathogen.

Gregorio Iraola
Samuel C. Forster
Trevor D. Lawley
ResearchOpen Access08 Nov 2017
Nature Communications

Volume: 8, P: 1-8
Genomic epidemiology reveals multiple introductions of Zika virus into the United States

Genome sequencing of Zika virus samples from infected patients and Aedes aegypti mosquitoes in Florida shows that the virus was probably introduced into the United States on multiple occasions, and that the Caribbean is the most likely source.

Nathan D. Grubaugh
Jason T. Ladner
Kristian G. Andersen
Research24 May 2017
Nature

Volume: 546, P: 401-405
Genome sequence of the Brown Norway rat yields insights into mammalian evolution

Richard A. Gibbs
George M. Weinstock
Francis Collins
Research01 Apr 2004
Nature

Volume: 428, P: 493-521
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

Hypermutation and microsatellite burden determine responses and long-term survival following PD-1 blockade in children and young adults with refractory cancers resulting from germline DNA replication repair deficiency.

Anirban Das
Sumedha Sudhaman
Uri Tabori
ResearchOpen Access06 Jan 2022
Nature Medicine

Volume: 28, P: 125-135
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Liquid explosions induced by X-ray laser pulses

X-ray-induced explosions in water drops, examined using time-resolved imaging, show interacting high-speed liquid and vapour flows. This type of X-ray absorption dynamics is predictable and may be used for inducing particular dynamical liquid states.

Claudiu A. Stan
Despina Milathianaki
Sébastien Boutet
Research23 May 2016
Nature Physics

Volume: 12, P: 966-971
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

The Human BioMolecular Atlas Program (HuBMAP) presents its production phase: the generation of spatial maps of functional tissue units across organs from diverse populations and the creation of tools and infrastructure to advance biomedical research.

Sanjay Jain
Liming Pei
Michael P. Snyder
Reviews19 Jul 2023
Nature Cell Biology

Volume: 25, P: 1089-1100
A thiol probe for measuring unfolded protein load and proteostasis in cells

Proteostasis is maintained through a number of molecular mechanisms, some of which function to protect the folded state of proteins. Here the authors demonstrate the use of TPE-MI in a fluorigenic dye assay for the quantitation of unfolded proteins that can be used to assess proteostasis on a cellular or proteome scale.

Moore Z. Chen
Nagaraj S. Moily
Danny M. Hatters
ResearchOpen Access07 Sept 2017
Nature Communications

Volume: 8, P: 1-11
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
A physical map of the human genome

John D. McPherson
Marco Marra
Hans Lehrach
Research15 Feb 2001
Nature

Volume: 409, P: 934-941
Endogenous kynurenines as targets for drug discovery and development

Trevor W. Stone
L. Gail Darlington
Reviews01 Aug 2002
Nature Reviews Drug Discovery

Volume: 1, P: 609-620
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Prediction of human population responses to toxic compounds by a collaborative competition

Crowdsourcing analysis improves computational prediction of cytotoxic responses in humans.

Federica Eduati
Lara M Mangravite
Julio Saez-Rodriguez
ResearchOpen Access01 Sept 2015
Nature Biotechnology

Volume: 33, P: 933-940
The Edwin Smith Surgical Papyrus: an analysis of the first case reports of spinal cord injuries

J Trevor Hughes
Reviews01 Apr 1988
Spinal Cord

Volume: 26, P: 71-82
Real-time evaluation of signal accuracy in wastewater surveillance of pathogens with high rates of mutation

Ocean Thakali
Élisabeth Mercier
Eli Zeeb
ResearchOpen Access14 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
Mouse microglia express unique miRNA-mRNA networks to facilitate age-specific functions in the developing central nervous system

Microglial miRNA signatures are characterised in the developing mouse brain, with specific miRNA-mRNA networks being associated with CNS development, immune function and dysregulated disease states.

Alexander D. Walsh
Sarrabeth Stone
Michele D. Binder
ResearchOpen Access22 May 2023
Communications Biology

Volume: 6, P: 1-16
A new, large-bodied omnivorous bat (Noctilionoidea: Mystacinidae) reveals lost morphological and ecological diversity since the Miocene in New Zealand

Suzanne J. Hand
Robin M. D. Beck
Trevor H. Worthy
ResearchOpen Access10 Jan 2018
Scientific Reports

Volume: 8, P: 1-11
Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

Trevor Beaudoin
Tracy A. Stone
Charles M. Deber
ResearchOpen Access03 Oct 2018
Scientific Reports

Volume: 8, P: 1-12

Search

Is adenosine the mediator of opiate action on neuronal firing rate?

A Fossil Human Mandible from a Levalloiso–Mousterian Horizon in Cyrenaica

Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus

Hominin presence in Eurasia by at least 1.95 million years ago

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

Grandmaster level in StarCraft II using multi-agent reinforcement learning

Fine-scale patterns of SARS-CoV-2 spread from identical pathogen sequences

Deformation and bursting of elastic capsules impacting a rigid wall

Cultural innovation and megafauna interaction in the early settlement of arid Australia

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Diminishing benefits of urban living for children and adolescents’ growth and development

Mapping the human genetic architecture of COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

Impacts of human mobility on the citywide transmission dynamics of 18 respiratory viruses in pre- and post-COVID-19 pandemic years

A second update on mapping the human genetic architecture of COVID-19

Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota

Genomic epidemiology reveals multiple introductions of Zika virus into the United States

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

Genetic mechanisms of critical illness in COVID-19

Liquid explosions induced by X-ray laser pulses

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

A thiol probe for measuring unfolded protein load and proteostasis in cells

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

A physical map of the human genome

Endogenous kynurenines as targets for drug discovery and development

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Prediction of human population responses to toxic compounds by a collaborative competition

The Edwin Smith Surgical Papyrus: an analysis of the first case reports of spinal cord injuries

Real-time evaluation of signal accuracy in wastewater surveillance of pathogens with high rates of mutation

Mouse microglia express unique miRNA-mRNA networks to facilitate age-specific functions in the developing central nervous system

A new, large-bodied omnivorous bat (Noctilionoidea: Mystacinidae) reveals lost morphological and ecological diversity since the Miocene in New Zealand

Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

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