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A synthetic biology approach was used to engineer Vibrio natriegens into a strain capable of bioremediating complex organic pollutants in saline wastewater and soils, thereby addressing notable threats to marine biosecurity.

Existing photo-controlled CRISPR diagnostic methods suffer from limited universality, high cost, and low detection efficiency. Here, the authors develop a photo-caging strategy designed for the direct repeat (DR) region of Cas12a crRNA, enabling a broadly applicable one-pot detection platform

Here, the authors report a high-performance broadband spectrometer based on a van der Waals heterostructure tunnel diode containing MoS₂ and and black phosphorus, leveraging their electrically tunable photoresponse and advanced computational algorithms for spectral reconstruction.

Chang’e-6 mission’s analysis of farside lunar soils reveals stronger magnetic properties than nearside samples and identifies distinct magmatic and impact-formed minerals. This offers insights into the Moon’s magnetic history and crustal anomalies.

Acoustic graphene plasmons (AGPs) hold promise for nanophotonics and sensing applications. Here, the authors observe enhanced in-plane scattering of mid-infrared AGPs caused by atomic steps on the substrate surface, suggesting potential strategies for controlling their propagation via substrate engineering.

Here, employing 2,270 metagenomic samples across 10 different ruminant species, the authors construct a catalogue of the ruminant gut archaeome, comprised of 998 nonredundant genomes, expanding knowledge on Archaea compositions, diversity, and functions across the gut biogeography of various ruminants.

Macrophages play a key role in atherosclerosis through lipid uptake and inflammation. Here, the authors show that RNF128 promotes atherosclerosis by stabilizing scavenger receptor B1 (SRB1) via polyubiquitination, enhancing foam cell formation and inflammation, while its ablation reduces plaque formation in hyperlipidemic mice.

Manufacturing of perovskite solar cells under ambient conditions is desirable. Meng et al. show that dimethylammonium formate suppresses halide oxidation and deprotonation of organic cations, enabling air-processed inverted solar cells with 24.7% efficiency.

Most LiDARs have an intrinsic tradeoff between acquisition rate and non-ambiguity range. Researchers demonstrated a LiDAR called RRMFC based on an integrated lithium niobate frequency comb, leading to a 1.79 GHz acquisition rate and infinite non-ambiguity range.

Among other exotic properties graphene exhibits the highest thermal conductivity observed so far. This is true at least for graphene composed of only ¹²C atoms. However, it is now shown experimentally that regions of ¹³C atoms can substantially reduce the thermal conductivity. Aside from their fundamental importance, these results suggest that thermal conductivity can be tailored by varying the relative amounts of carbon isotopes used.

A large range of inert and non-defective sites in catalysts is a primary factor impeding catalyst activity in acidic CO₂ electroreduction. Here, the authors achieve high HCOOH selectivity and activity in acidic electrolyte by introducing tensile strain to activate inert sites.

Parket al. use ¹³C and ¹⁵N solid-state NMR and X-ray photoelectron spectroscopy to study the chemical structure of hydrazine-treated graphite oxide. Hydrazine treatment is shown to lead to the incorporation of aromatic N₂moieties at the graphene edges and restore graphitic networks on the basal planes.

Worldwide, the number of only-child families is increasing. This research examines how growing up without siblings affects adult brain structure, function and connectivity, cognition, personality and mental health.

Researchers demonstrate the high-coherence parallelization in integrated photonics. Their high-coherence, high-power, multiwavelength light source drives a silicon photonic link with a 60 Tbit/s data rate and significantly reduces digital signal processing consumption.

Socioeconomic status is multidimensional and can change over time. Xu, Lui, Ji et al. found dimension-specific, late-stage-specific and change-specific socioeconomic effects on brain, cognition, personality and emotion.

Patients treated for multiple myeloma often experience relapse due to antigen loss, thus necessitating the identification of additional therapeutic targets. In this study, the authors demonstrate that FcRH5 is expressed on MM cells and can be targeted using chimaeric antigen receptor T cells in mice.

The authors reveal a mechanism in understanding the responses to Ralstonia solanacearum in pepper under high temperature and high humidity conditions, that is differential associations between transcription factors mediate distinct immune and heat responses.

The current use of elastography ultrasound faces challenges, including vulnerability to subjective manipulation, echo signal attenuation, unknown risks of elastic pressure and high imaging hardware cost. Here, the author shows a virtual elastography to empower low-end ultrasound devices with state-of-art elastography function.

Hydrogen produced directly from neutral seawater is promising but challenging due to seawater’s complex composition. Here, the authors report a Na⁺-conducted pH-asymmetric electrolyzer that can directly split seawater into hydrogen with low electricity cost and nearly zero chloride interference.

Phosphoantigen-mediated BTN2A1 association drives BTN3A1 intracellular fluctuations outwards in a thermodynamically favourable manner, thereby enabling BTN3A1 to push off from the BTN2A1 ectodomain to initiate T cell receptor–mediated γδ T cell activation.

Proton transfer across graphene is associated with large computed energy barriers and is thought to be generally unfavourable. Here, the authors observe aqueous proton transfer through graphene subjected to pH cycling, suggesting that it is due to transfer through rare, naturally occurring atomic defects.

Inhibition of intestinal MYC is shown to have beneficial metabolic effects by promoting GLP-1 secretion and reducing ceramide production.

Evolution of accretion disk and corona during outbursts in black hole binary systems is still unclear. Here, the authors show spectral analysis of MAXI J1820+070 and propose a scenario of a dynamical corona to explain the evolution of the reflection fraction observed by Insight-HXMT.

A high-dimensional photodetection system that combines a lens and a thin-film interface enables simultaneous measurements of light spectrum and polarization states, with the aid of a deep neural network.

Cross-ancestry genome-wide association studies of 3,414 brain imaging phenotypes in Chinese Han and white British participants identify autosomal and X-chromosomal associations in more diverse populations.

The transcription factor retinoid X receptor-alpha (RXRα) can also form homotetramers. Here the authors show that the anti-cancer agent K-80003 selectively inhibits the nongenomic action of N-terminally-cleaved RXRα in tumour cells by stabilizing its tetramerization but not that of full-length RXRα.

Jun Wang and colleagues report the genome sequence of the cucumber. The cucumber genome is the seventh plant genome sequence to be reported and was assembled with a combination of traditional Sanger and next-generation sequencing methods.

Genome-wide association meta-analyses in populations of East Asian and European ancestries identify variant–trait associations for 44 hippocampal traits and provide insight into the genetic architectures of hippocampal and subfield volumes.

Liu and colleagues show that a previously described G396R variant of the human IGHG1 gene offers increased protection from SARS-CoV-2 and bacterial infections.