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Integrative analyses of transcriptome and whole-genome sequencing data for 1,188 tumours across 27 types of cancer are used to provide a comprehensive catalogue of RNA-level alterations in cancer.

A genome-wide study by the Long COVID Host Genetics Initiative identifies an association between the FOXP4 locus and long COVID, implicating altered lung function in its pathophysiology.

Ginzburg–Landau theory provides a powerful framework for describing the behaviour of conventional superconductors without detailed microscopic information about them. Bao et al.construct a similar framework for describing spin superconductivity, a recently proposed analogue of conventional superconductivity.

High-entropy ceramics are solid solutions offering compositional flexibility and wide variety of applicability. High-entropy concepts are shown to lead to substantial performance improvement in cation-disordered rocksalt-type cathodes for Li-ion batteries.

Insight-HXMT detected a double-peaked X-ray burst from Galactic magnetar SGR J1935+2154, consistent with two fast radio bursts (FRBs) observed from the same object within seconds. This coincidence suggests a common physical origin, and gives insight into the mechanism behind the origin of FRBs.

It is extremely difficult to separate tritium from radioactively contaminated water. Here the authors introduce catalytic hydrogen isotope exchange to water distillation, realizing excellent detritiation performance.

Fibers derived from non-silk proteins hold potential for various biomedical applications, but mechanically-balanced and highly-biocompatible regenerated protein fibers are elusive. Here, the authors report an entanglement-reinforced strategy to fabricate keratin/albumin bio-fibers that show high strength and toughness, along with favorable biocompatibility, degradability and immunocompatibility.

The Van Allen radiation belts are two zones of energetic particles encircling the Earth, but how electrons are accelerated to relativistic energies remains unclear. Here, the authors analyse a radiation belt event and provide evidence in favour of the ULF wave-driven radial diffusion mechanism.

Angle-resolved photoemission spectroscopy of CaNi₂ shows a band with vanishing dispersion across the full 3D Brillouin zone that is identified with the pyrochlore flat band as well as two additional flat bands that arise from multi-orbital interference of Ni d-electrons.

A consensus cell type atlas for the fly brain provides both an intellectual framework and open-source toolchains for brain-scale comparative connectomics.

Iron pnictide compounds have recently been shown to have superconducting properties. Xuet al. show that the superconducting gap of underdoped pnictides scales linearly with the transition temperature, and that a pseudogap develops with underdoping.

High-throughput computational screening of multicomponent molecular photocatalytic systems offers a strategy to minimize the screening of large numbers of photosensitizer–catalyst combinations. Here a machine learning-accelerated approach using multiple descriptors shows strong predictive power in experimentally validated systems for CO₂ reduction.

Non-invasive brain stimulation (NIBS) shows considerable promise as a therapeutic strategy for neurological and psychiatric disorders. This Review explores the role of NIBS techniques, including repetitive transcranial magnetic stimulation and transcranial electrical stimulation, for treating cognitive impairments, speech and language difficulties, and motor control deficits in people with neurodegenerative or brain lesion disorders.

The authors report an in-situ x-ray diffraction study of pressure and strain-induced phase transformations in silicon, an essential electronic material. They observe several different plastic strain-induced transformation phenomena which may inspire practical applications.

Neural Decomposition (NEURD) is a software package that decomposes neuronal data from high-resolution electron microscopy volumes into feature-rich graph representations to facilitate analysis for neuroscience research.

The authors find the magnon spin transport in CrSP₄/Pt (Ta) can be effectively modulated through adjustments in temperature and applied magnetic field, particularly at the spin-flip field.

Free-electron lasers (FELs) can produce bright X-ray pulses, but require high quality electron beams. Here the authors show how to generate and preserve ultrabright electron beams from plasma-based accelerators for ultra-compact, high-brightness X-ray FELs.

It remains unclear why some decisions take longer than others even when the sensory inputs are similar. Here, the authors show that both initial neural state and sensory input combine in the premotor cortex to influence the speed and geometry of neural population activity during decisions.

Experiments at the Joint European Torus tokamak show improved thermal ion confinement in the presence of highly energetic ions and Alfvénic instabilities in the plasma.

The authors study CsV₃Sb₅ by nuclear quadrupole resonance. At ambient pressure, there are two superconducting gaps with line nodes in the smaller one. For pressures above P_c ~ 1.85 GPa, where the charge-density wave phase is completely suppressed, they observe fully-gapped superconductivity with broken rotational symmetry.

Using differential phase contrast imaging and density-functional theory, the authors identify and explain observations of well-ordered interface-stabilized phase states (referred to as complexions) at the iron/magnetite interface.

Spin injection in pure topological surface states of topological insulators is challenging due to the coexistence of highly conducting bulk states. Here, Song et al. report spin injection and inverse Edelstein effect in the spin–momentum locked surface states of topological Kondo insulator SmB₆.

Superconducting single-photon detectors are critical for quantum communication, fluorescence lifetime imaging and remote sensing, but commonly operate at very low temperatures. Now, high-temperature cuprate superconducting nanowires enable single-photon detection up to 25 K.

The authors predict the Pockels effect of ScAlN with varying Sc concentration, realizing a ScAlN-on-insulator-on-silicon material platform, which allows the formation of low-loss, electrically-tunable microring resonators for accurate measurement of ScAlN’s Pockels coefficients.

Probing the explosion of nitrous oxide ions in real time using high-harmonic radiation and infrared laser pulses now provides insight into the correlated dynamics of electrons and nuclei during photoionization.

The anomalous Hall effect has been observed in high-quality epitaxial thin films of non-collinear antiferromagnet Mn₃Pt, and can be switched on and off using an electric field.

Barocaloric materials, undergoing thermal changes in response to applied pressure, may provide energy efficient and zero-emission solid-state cooling. Here the authors report a mechanism for achieving large reversible barocaloric effects near ambient temperature, leveraging volume and conformational entropy changes within the organic bilayers of two-dimensional metal–halide perovskites.

Solar-driven carbon dioxide reduction has witnessed a renaissance in the past decades, but the system suffers from low reaction rates. Here the authors develop a copper/tin-oxide electrocatalyst, achieving a new benchmark solar-to-CO energy conversion efficiency in a flow electrolyzer.

Knowledge of effective Coulomb interactions is central to understand emergent quantum phases in strongly correlated systems. Here, Boschini et al. report a dynamic quasi-circular spectrum of charge density wave fluctuations in the CuO₂ plane of Bi₂Sr₂CaCu₂O_8+δ, shedding a light on understanding how Coulomb interactions can lead to rotational and translational symmetry breaking in the cuprates.

Polycyclic aromatic hydrocarbons play an important role in interstellar chemistry, where interaction with high energy photons can induce ionization and fragmentation reactions. Here the authors, with XUV-IR pump-probe experiments, investigate the ultrafast photoinduced dynamics of fluorene, phenanthrene and pyrene, providing insight into their preferred reaction channels.

Plasma turbulence is the main driver to deteriorate the performance of fusion power plants. This work presents an unprecedented comparison of plasma turbulence between experiment and simulation, proving that the gyrokinetic model GENE reached a high level of maturity to predict core turbulence.

A magnetoresistance effect that occurs in a platinum layer deposited on a magnon junction consisting of two insulating magnetic yttrium iron garnet layers separated by an antiferromagnetic nickel oxide spacer layer could be used to create spintronic and magnonic devices that are free from Joule heating.

6R-TaS2 is a natural van der Waals heterostructure formed by 1H- and 1T-phase TaS₂ layers, which can individually exhibit Ising superconductivity, correlated states and charge density waves. Here, the authors show experimental evidence of emergent nematic Ising superconductivity with simultaneous hidden magnetism (extrinsic anomalous Hall effect and Kondo screening) in 6R-TaS₂ under 30 K.

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

Time resolved measurements provide insights to the intriguing process of ultrafast molecular fragmentation. Here the authors use CEP-locked laser pulses in pump–probe scheme to explore the H₂⁺dissociation and find out that the electron localization to one of the nuclei occurs in about 15 fs.

Quantum teleportation has found important applications in quantum technologies, but pushing it to macroscopic objects is challenging because of the fragility of quantum states. Here, the authors demonstrate teleportation of states from light beams to the vibrational states of a macroscopic diamond sample.

Climate change effects on food webs may be modulated by ecological variables. Here, the authors report how planktonic food web stability depends on temperature and biodiversity, and show that trophic dynamics and synchrony help elucidate the patterns.

The poor structural stability of cathode materials is responsible for the rapid capacity loss of sodium-ion batteries during cycling. This work addresses the instability by introducing vacancies into the transition metal layers and realize long-life pouch cells.

This work employs nano- to microscale characterization to identify different structural change pathways associated with non-homogeneous reactions within the particles, and explores differences in the failure mechanisms of lithium-rich transition metal oxide materials at different current densities.