Nature Search

Helicobacter pylori antimicrobial resistance and gene variants in Shandong Province

Zhijing Xue
Qi Zhao
Guohai Su
ResearchOpen Access01 Oct 2025
Scientific Reports

Volume: 15, P: 1-12
Tandem polymer solar cells featuring a spectrally matched low-bandgap polymer

Researchers demonstrate that PBDTT-DPP, a semiconducting polymer with a low bandgap of 1.44 eV, allows tandem polymer solar cells to reach power conversion efficiencies of around 8.6%.

Letian Dou
Jingbi You
Yang Yang
Research12 Feb 2012
Nature Photonics

Volume: 6, P: 180-185
Highly dynamic and sensitive NEMOer calcium indicators for imaging ER calcium signals in excitable cells

The endoplasmic/sarcoplasmic reticulum (ER/SR) plays a crucial role in calcium signaling, but there are few methods capable of efficiently capturing ER/SR Ca²⁺ dynamics. Here authors develop a set of genetically encoded indicators enabling ratiometric super-resolution imaging and detection of elementary Ca²⁺ release in cardiomyocytes.

Wenjia Gu
Jia-Hui Chen
Youjun Wang
ResearchOpen Access11 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells

Li et al. report that co-delivering a dominant negative fragment of p53 (p53DD) greatly enhances precise editing efficiencies for prime editing and cytosine base editing in human pluripotent stem cells, without compromising the genome-wide safety.

Mu Li
Aaron Zhong
Ting Zhou
ResearchOpen Access27 Oct 2022
Nature Communications

Volume: 13, P: 1-12
A stable and biocompatible shortwave infrared nanoribbon for dual-channel in vivo imaging

While the shortwave infrared (SWIR) region has potential for bioimaging applications, stable and biocompatible SWIR absorbers/emitters are challenging to access. Here, the authors report the approach of crystal-aided aggregate synthesis for the development of J-aggregates for in vivo bioimaging.

Cheng Yao
Ruwei Wei
Youjun Yang
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-12
Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase

Here the authors use cryo-electron microscopy to provide insights into fatty acid recycling by an acyl-acyl carrier protein (ACP) synthesizing enzyme, showing a transition from a hexameric to tetrameric form in the process of acyl-ACP production.

Haomin Huang
Chen Wang
Youjun Feng
ResearchOpen Access10 Jan 2025
Nature Structural & Molecular Biology

Volume: 32, P: 802-817
Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity

The human tumor suppressor p53 interacts with the BCL-2 family proteins to regulate apoptosis. Here, the authors solve the structures of p53 in complex with the antiapoptotic protein BCL-2 and suggest a mechanism by which p53 promotes apoptosis by competitively antagonizing the interaction of BCL-2 with pro-apoptotic BCL-2 family proteins.

Hudie Wei
Haolan Wang
Yongheng Chen
ResearchOpen Access18 Jul 2023
Nature Communications

Volume: 14, P: 1-13
Genome assembly of wild tea tree DASZ reveals pedigree and selection history of tea varieties

Wild teas are considered as valuable resource for studying domestication and breeding. Here, Zhang et al. report genome of wild tea DASZ and transcriptome of 217 accessions, which clarify pedigree of Chinese tea cultivars and show tea may not have undergone long-term artificial directional selection on flavor-related metabolites.

Weiyi Zhang
Youjun Zhang
Weiwei Wen
ResearchOpen Access24 Jul 2020
Nature Communications

Volume: 11, P: 1-12
Engineering of NEMO as calcium indicators with large dynamics and high sensitivity

The NEMO series of genetically encoded calcium indicators report calcium activity in neuronal and non-neuronal cells with high signal-to-baseline ratio, which is shown in neuronal culture, slice preparations, in vivo and in planta.

Jia Li
Ziwei Shang
Youjun Wang
ResearchOpen Access20 Apr 2023
Nature Methods

Volume: 20, P: 918-924
The isotopic effects of deuteration on optoelectronic properties of conducting polymers

Isotopic substitution alters the optoelectronic properties of conducting polymers, but a microscopic understanding is still missing. Shao et al.address this effect using a series of polymer isotopes that are synthesized with deuterium atoms substituted either on their backbone or side chains.

Ming Shao
Jong Keum
Kai Xiao
Research24 Jan 2014
Nature Communications

Volume: 5, P: 1-11
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline

HDAC6 is a tau deacetylase and acetylation of tau inhibits its function and promotes aggregation. Here the authors show that HDAC6 protects against tau accumulation in a mouse model of tauopathy.

Hanna Trzeciakiewicz
Deepa Ajit
Todd J. Cohen
ResearchOpen Access02 Nov 2020
Nature Communications

Volume: 11, P: 1-18
Virus infection of a weed increases vector attraction to and vector fitness on the weed

Gong Chen
Huipeng Pan
Youjun Zhang
ResearchOpen Access22 Jul 2013
Scientific Reports

Volume: 3, P: 1-6
Response spectra and design spectrum of ground fissures site under seismic action

Chao Zhang
Weining Zhong
Youjun Xu
ResearchOpen Access08 May 2025
Scientific Reports

Volume: 15, P: 1-12
A diversity-oriented rhodamine library for wide-spectrum bactericidal agents with low inducible resistance against resistant pathogens

Preparation of xanthene-containing compounds has been limited due to structural bias existing methods pose. Here, the authors developed a mild, diversity-oriented method for rhodamines synthesis, leading to the finding of compounds with antibacterial potency against a variety of bacterial species.

Xiao Luo
Liujia Qian
Youjun Yang
ResearchOpen Access16 Jan 2019
Nature Communications

Volume: 10, P: 1-12
Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome

Dysregulation of mTOR signaling has been implicated in autism spectrum disorders. Here authors show that hyperconnectivity and hyperactivity of the mPFC–BLA circuitry inPten^+/−mice underlies their social impairments, and that reducing mTORC1 signaling during early postnatal development rescues these deficits.

Wen-Chin Huang
Youjun Chen
Damon T. Page
ResearchOpen Access15 Nov 2016
Nature Communications

Volume: 7, P: 1-15
Pancreatic human islets and insulin-producing cells derived from embryonic stem cells are rapidly identified by a newly developed Dithizone

Bashar Khiatah
Meirigeng Qi
Ismail H. Al-Abdullah
ResearchOpen Access26 Jun 2019
Scientific Reports

Volume: 9, P: 1-6
FXR inhibition functions as a checkpoint blockade of the pathogenic Tfh cell response in lupus

Xiangyang Wang
Linsen Ye
Yingjiao Cao
Research25 Jun 2025
Cellular & Molecular Immunology

Volume: 22, P: 889-900
Tomato yellow leaf curl virus alters the host preferences of its vector Bemisia tabaci

Yong Fang
Xiaoguo Jiao
Youjun Zhang
ResearchOpen Access07 Oct 2013
Scientific Reports

Volume: 3, P: 1-5
Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

Plasmid-encoded tet(X) genes from Escherichia coli in China confer high-level tigecycline resistance.

Jian Sun
Chong Chen
Ya-Hong Liu
Research24 Jun 2019
Nature Microbiology

Volume: 4, P: 1457-1464
A wide star–black-hole binary system from radial-velocity measurements

Radial-velocity measurements of a Galactic B-type star show a dark companion that seems to be a black hole of about 68 solar masses, in a widely spaced binary system.

Jifeng Liu
Haotong Zhang
Xiangqun Cui
Research27 Nov 2019
Nature

Volume: 575, P: 618-621
RNA N⁶-methyladenosine demethylase FTO promotes diabetic wound healing through TRIB3-mediated autophagy in an m⁶A-YTHDF2-dependent manner

Zheng Dong
Shiyan Li
Qian Tan
ResearchOpen Access29 Mar 2025
Cell Death & Disease

Volume: 16, P: 1-16
Proteomic mapping of ER–PM junctions identifies STIMATE as a regulator of Ca²⁺ influx

Through a proteomic analysis of ER–PM junctions, Zhou and colleagues and Wang and colleagues discover that the transmembrane protein STIMATE is a positive regulator of STIM localization and function, thereby stimulating Ca²⁺ influx.

Ji Jing
Lian He
Yubin Zhou
Research31 Aug 2015
Nature Cell Biology

Volume: 17, P: 1339-1347
Preferential allosteric modulation of Otop1 channels by small molecule compounds

Functional characterization of preferential and potent small molecule modulators that allosterically enhance the gating of the Otop1 channel by targeting its key gating apparatus

Xiangjin Kong
Jie Sun
Cheng Tang
ResearchOpen Access26 Feb 2025
Communications Biology

Volume: 8, P: 1-11
Rapid on-site differentiation of two invasive whitefly cryptic species using LAMP

Yage Liu
Lifeng Yang
Dong Chu
ResearchOpen Access12 Feb 2025
Scientific Reports

Volume: 15, P: 1-8
p53 promotes peroxisomal fatty acid β-oxidation to repress purine biosynthesis and mediate tumor suppression

Jianhong Zhao
Xiaojun Zhou
Youjun Li
ResearchOpen Access07 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-15
Comparative physiological and transcriptomic analyses reveal genotype specific response to drought stress in Siberian wildrye (Elymus sibiricus)

Yongping An
Qian Wang
Pei Wang
ResearchOpen Access10 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Shear mechanical response and deformation failure of F-type socket joint in a rectangular pipe jacking tunnel under different geologic conditions

Youjun Xu
Zhengrong Zhao
Yuekui Pang
ResearchOpen Access11 Dec 2023
Scientific Reports

Volume: 13, P: 1-16
Combination of S100A12/TLR2 signaling molecules and clinical indicators in a new predictive model for IVIG-resistant Kawasaki disease

Yali Wu
Pan Liu
Yan Ding
ResearchOpen Access27 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Direct control of store-operated calcium channels by ultrafast laser

Pan Cheng
Xiaoying Tian
Hao He
ResearchOpen Access19 Jan 2021
Cell Research

Volume: 31, P: 758-772
Virome analysis for identification of novel mammalian viruses in bats from Southeast China

Dan Hu
Changqiang Zhu
Changjun Wang
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-12
Genome characterization of two bile-isolated Vibrio fluvialis strains: an insight into pathogenicity and bile salt adaption

Beiwen Zheng
Xiawei Jiang
Lanjuan Li
ResearchOpen Access19 Sept 2017
Scientific Reports

Volume: 7, P: 1-10
Bemisia tabaci Q carrying tomato yellow leaf curl virus strongly suppresses host plant defenses

Xiaobin Shi
Huipeng Pan
Youjun Zhang
ResearchOpen Access10 Jun 2014
Scientific Reports

Volume: 4, P: 1-7
A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Autofluorescence: Preparation, Characterization and In Vivo Biodegradation Tracking and Modeling

Xiaoyu Ma
Xiangcheng Sun
Yu Lei
ResearchOpen Access27 Jan 2016
Scientific Reports

Volume: 6, P: 1-12
Net primary productivity and its partitioning in response to precipitation gradient in an alpine meadow

Fangyue Zhang
Quan Quan
Shuli Niu
ResearchOpen Access09 Nov 2017
Scientific Reports

Volume: 7, P: 1-10
Evidence For Rapid Spatiotemporal Changes in Genetic Structure of an Alien Whitefly During Initial Invasion

Dong Chu
Dong Guo
Youjun Zhang
ResearchOpen Access18 Mar 2014
Scientific Reports

Volume: 4, P: 1-6
miR-148a inhibits colitis and colitis-associated tumorigenesis in mice

Yahui Zhu
Li Gu
Youjun Li
Research29 Sept 2017
Cell Death & Differentiation

Volume: 24, P: 2199-2209

Search

Helicobacter pylori antimicrobial resistance and gene variants in Shandong Province

Tandem polymer solar cells featuring a spectrally matched low-bandgap polymer

Highly dynamic and sensitive NEMOer calcium indicators for imaging ER calcium signals in excitable cells

Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells

A stable and biocompatible shortwave infrared nanoribbon for dual-channel in vivo imaging

Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase

Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity

Genome assembly of wild tea tree DASZ reveals pedigree and selection history of tea varieties

Engineering of NEMO as calcium indicators with large dynamics and high sensitivity

The isotopic effects of deuteration on optoelectronic properties of conducting polymers

An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline

Virus infection of a weed increases vector attraction to and vector fitness on the weed

Response spectra and design spectrum of ground fissures site under seismic action

A diversity-oriented rhodamine library for wide-spectrum bactericidal agents with low inducible resistance against resistant pathogens

Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome

Pancreatic human islets and insulin-producing cells derived from embryonic stem cells are rapidly identified by a newly developed Dithizone

FXR inhibition functions as a checkpoint blockade of the pathogenic Tfh cell response in lupus

Tomato yellow leaf curl virus alters the host preferences of its vector Bemisia tabaci

Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

A wide star–black-hole binary system from radial-velocity measurements

RNA N⁶-methyladenosine demethylase FTO promotes diabetic wound healing through TRIB3-mediated autophagy in an m⁶A-YTHDF2-dependent manner

Proteomic mapping of ER–PM junctions identifies STIMATE as a regulator of Ca²⁺ influx

Preferential allosteric modulation of Otop1 channels by small molecule compounds

Rapid on-site differentiation of two invasive whitefly cryptic species using LAMP

p53 promotes peroxisomal fatty acid β-oxidation to repress purine biosynthesis and mediate tumor suppression

Comparative physiological and transcriptomic analyses reveal genotype specific response to drought stress in Siberian wildrye (Elymus sibiricus)

Shear mechanical response and deformation failure of F-type socket joint in a rectangular pipe jacking tunnel under different geologic conditions

Combination of S100A12/TLR2 signaling molecules and clinical indicators in a new predictive model for IVIG-resistant Kawasaki disease

Direct control of store-operated calcium channels by ultrafast laser

Virome analysis for identification of novel mammalian viruses in bats from Southeast China

Genome characterization of two bile-isolated Vibrio fluvialis strains: an insight into pathogenicity and bile salt adaption

Bemisia tabaci Q carrying tomato yellow leaf curl virus strongly suppresses host plant defenses

A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Autofluorescence: Preparation, Characterization and In Vivo Biodegradation Tracking and Modeling

Net primary productivity and its partitioning in response to precipitation gradient in an alpine meadow

Evidence For Rapid Spatiotemporal Changes in Genetic Structure of an Alien Whitefly During Initial Invasion

miR-148a inhibits colitis and colitis-associated tumorigenesis in mice

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