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Showing 1–19 of 19 results
Advanced filters: Author: Yuchao Ni Clear advanced filters

  • ATG16L1 is a key autophagic protein. Here, the authors elucidate the molecular basis of ATG16L1 interactions with FIP200 and ATG8 family proteins, showing that the interaction of ATG16L1 with FIP200 is indispensable for the effective autophagic flux.

    • Xinyu Gong
    • Yuqian Zhou
    • Lifeng Pan
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Nanoscale metal inclusions play an important role in solid-state dielectric devices. Here, the authors demonstrate that these inclusions can change their shape, size and position in response to an applied electric field, and that electrochemical processes can lead to metal cluster nucleation and growth.

    • Yuchao Yang
    • Peng Gao
    • Wei D. Lu
    Research
    Nature Communications
    Volume: 5, P: 1-9

  • Currently, there is limited understanding of the molecular subtypes of fumarate hydratase (FH)-deficient renal cell carcinoma (RCC). Here, the authors employ integrated genomics and transcriptomics to develop a CpG site-specific methylation signature for the identification of FH-deficient RCC, and to identify three distinct molecular subtypes for this rare but highly lethal kidney cancer.

    • Xingming Zhang
    • Junjie Zhao
    • Guangxi Sun
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • RNF213 is a key player in fighting against various invasive pathogens in mammals. Here, the authors show that pathogenic Shigella flexneri can use its effector IpaH1.4 to directly target and subvert RNF213 to evade host antibacterial immunity.

    • Xindi Zhou
    • Huijing Zhang
    • Lifeng Pan
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Developing a generalizable method for blocking and rescuing tryptophan (Trp) interactions would enable the gain-of-function manipulation of various Trp-containing proteins but has so far been challenging. Now a genetically encoded N1-vinyl-caged Trp capable of rapid and bioorthogonal decaging enables site-specific activation of Trp on a protein of interest within living cells.

    • Yuchao Zhu
    • Wenlong Ding
    • Peng R. Chen
    Research
    Nature Chemistry
    Volume: 16, P: 533-542

  • The transfer of 2D semiconductor films remains a challenging step in the fabrication of industry-compatible 2D electronics. Here, the authors report a method based on a Se intermediate layer to facilitate the transfer of wafer-scale MoS2 monolayers with nearly 100% film intactness and superior surface/interface cleanness, leading to an improved electrical performance of the devices.

    • Xingchao Zhang
    • Lanying Zhou
    • Guangyu Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8

  • Transcription factors are crucial in disease but hard to target with traditional drugs. Here, authors present BlockerSELEX, a strategy to develop inhibitory aptamers that block transcription factor interactions, which disrupts interactions between key proteins, showing potential for new nucleic acid therapies.

    • Tongqing Li
    • Xueying Liu
    • Weihong Tan
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Chen et al. present a filament conductivity change mechanism in memristive devices with all ohmic electrodes, allowing for advanced functionalities and more effective emulation of the metaplasticity concept in neuroscience.

    • Shaochuan Chen
    • Zhen Yang
    • Ilia Valov
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Quasi-solid-state Zn-air batteries are limited by sluggish kinetics and low temperature incompatibility. Here, the authors use a single-atom catalyst and an organohydrogel electrolyte to enable a 100 mA cm−2 cycling current density at 25 °C and a −60 to 60 °C operational window.

    • Qichen Wang
    • Qingguo Feng
    • Xiang Xiong
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • SIRT1 is a stress sensor whose deacetylase activity is increased during cellular stress, but the molecular mechanism is unclear. Here, the authors show that O-GlcNAcylation of SIRT1 is elevated upon different stress stimuli and increases SIRT1 deacetylase activity, protecting cells from stress-induced apoptosis.

    • Cuifang Han
    • Yuchao Gu
    • Wengong Yu
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • A freeform multimaterial assembly process (FMAP) is demonstrated, synchronizing laser induction with 3D printing for seamlessly integrating multimaterials into 3D objects, enabling streamlined, flexible, and precise electronic device fabrication.

    • Bujingda Zheng
    • Yunchao Xie
    • Jian Lin
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • TFE3-translocation renal cell carcinoma (TFE3-tRCC) is a rare subtype of kidney cancer with no standard treatment options for the advanced disease. Here, the authors perform genomic and transcriptomic profiling of 63 untreated primary TFE3-tRCC tumours and reveal potential therapeutic targets.

    • Guangxi Sun
    • Junru Chen
    • Hao Zeng
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • Aldehyde dehydrogenase 1B1-specific small-molecule inhibitors are identified that block the growth of colon cancer spheroids and organoids and are shown to potentially regulate mitochondrial metabolism and ribosomal function.

    • Zhiping Feng
    • Marisa E. Hom
    • James K. Chen
    Research
    Nature Chemical Biology
    Volume: 18, P: 1065-1075

  • Rose is one of the most popular ornamental plants with crucial ecological, cultural and economic value. Here, the authors generated a high-quality telomere-to-telomere genome for the ancestor of tea rose, as well as investigated the release rhythm and regulatory networks of the special tea scent.

    • Lijun Zhou
    • Sihui Wu
    • Qixiang Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Simultaneous electrodeposition of metals facilitates the realization of memrisitive devices with high yield and improved reliability.

    • Ilia Valov
    • Yuchao Yang
    News & Views
    Nature Nanotechnology
    Volume: 15, P: 510-511

  • Limitations associated with the primary amination of aryl C–H bonds include the poor control of regioselectivity with electron-rich substrates and the challenging nature of the reaction in the case of electron-deficient arenes. Now, site-directed C–C bond primary amination of simple alkylarenes and benzyl alcohols provides a route for the direct and efficient preparation of anilines.

    • Jianzhong Liu
    • Xu Qiu
    • Ning Jiao
    Research
    Nature Chemistry
    Volume: 11, P: 71-77

  • Thermally activated delayed fluorescence (TADF) emitters are promising electroluminescent materials for next-generation organic light-emitting diodes (OLEDs). In this Review, the molecular design, photophysical characteristics and OLEDs composed of small-molecule, dendritic and polymeric TADF emitters are discussed.

    • Yuchao Liu
    • Chensen Li
    • Martin R. Bryce
    Reviews
    Nature Reviews Materials
    Volume: 3, P: 1-20