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Showing 1–50 of 54 results

Advanced filters: Author: Zhi-yong Liu Clear advanced filters

Enantioselective synthesis of β- and α-amino ketones through reversible alkane carbonylation

Alkane carbonylation through photocatalytic alkyl radical addition to CO is a challenge. Now, an equilibrium-leveraging strategy which combines the direct carbonylation of alkanes with CO with onwards enantioselective transformations is reported, providing an enantioselective method for the synthesis of β-amino and α-amino ketones.

Wei-Wei Ding
Zhi-Yuan He
Liu-Zhu Gong
Research17 Jan 2024
Nature Synthesis

Volume: 3, P: 507-516
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting

Proteomics can aid in the identification of molecular subtypes in cancers. Here, the authors perform proteomic profiling of 124 paired oesophageal cancer and adjacent non-tumour tissues and identify two subtypes that are associated with patient survival for therapeutic targeting.

Wei Liu
Lei Xie
En-Min Li
ResearchOpen Access16 Aug 2021
Nature Communications

Volume: 12, P: 1-18
Rapid and accurate multi-phenotype imputation for millions of individuals

Here the authors developed a multi-phenotype imputation method termed PIXANT by leveraging efficient machine learning (ML)-based algorithms.

Lin-Lin Gu
Hong-Shan Wu
Ming Fang
ResearchOpen Access04 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

Li-Dong Wang
Fu-You Zhou
Xue-Jun Zhang
Amendments and Corrections01 Sept 2014
Nature Genetics

Volume: 46, P: 1041
Twin-field quantum key distribution over a 511 km optical fibre linking two distant metropolitan areas

A field test of twin-field quantum key distribution was implemented through a 511 km optical fibre. To this end, precise wavelength control of remote independent laser sources and fast time- and phase-compensation systems are developed.

Jiu-Peng Chen
Chi Zhang
Jian-Wei Pan
Research21 Jun 2021
Nature Photonics

Volume: 15, P: 570-575
Carbachol inhibits TNF-α-induced endothelial barrier dysfunction through alpha 7 nicotinic receptors

Yu-zhen Li
Xiu-hua Liu
Zhi-yong Sheng
Research27 Sept 2010
Acta Pharmacologica Sinica

Volume: 31, P: 1389-1394
Recurrence of positive SARS-CoV-2 viral RNA in recovered COVID-19 patients during medical isolation observation

Bo Yuan
Han-Qing Liu
Shuo Song
ResearchOpen Access17 Jul 2020
Scientific Reports

Volume: 10, P: 1-7
Acteoside ameliorates cerebral ischemia/reperfusion injury in MCAO rats as a natural plasma Kallikrein inhibitor from Osmanthus fragrans flower

Hui-hao Wang
Kai-rui Feng
Li Liu
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-10
Continental drift and plateau uplift control origination and evolution of Asian and Australian monsoons

Xiaodong Liu
Buwen Dong
Qingchun Guo
ResearchOpen Access13 Jan 2017
Scientific Reports

Volume: 7, P: 1-8
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

Li-Dong Wang
Fu-You Zhou
Xue-Jun Zhang
Research22 Aug 2010
Nature Genetics

Volume: 42, P: 759-763
A circuit from the ventral subiculum to anterior hypothalamic nucleus GABAergic neurons essential for anxiety-like behavioral avoidance

Anxiety is thought to be evolutionarily rooted in predator defense. Yan et al. show that GABAergic neurons in the anterior hypothalamic nucleus (AHN), a node in the predator defense network, play an essential role in anxiety-like behaviors.

Jing-Jing Yan
Xiao-Jing Ding
Xiao-Hong Xu
ResearchOpen Access03 Dec 2022
Nature Communications

Volume: 13, P: 1-16
Quantum memory assisted entropic uncertainty relation as a signature of quantum phase transition in the spin XXZ model

Cheng-Cheng Liu
Ze-Wei Sun
Liu Ye
ResearchOpen Access03 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Effect of consolidation chemotherapy following definitive chemoradiotherapy in patients with esophageal squamous cell cancer

Sheng-Xi Wu
Xu-Yuan Li
Zhi-Yong Wu
ResearchOpen Access04 Dec 2017
Scientific Reports

Volume: 7, P: 1-5
Revealing the chirality origin and homochirality crystallization of Ag₁₄ nanocluster at the molecular level

The preparation of chiral monolayer-protected metal clusters is interesting for their potential applications in a variety of fields, including catalysis. Here, the authors synthesize chiral Ag₁₄ nanoclusters in an all-achiral environment, and decipher the origin of chirality at the molecular level; the solvent choice is key to achieve homochiral crystallization.

Xiao-Qian Liang
Ying-Zhou Li
Di Sun
ResearchOpen Access17 Aug 2021
Nature Communications

Volume: 12, P: 1-10
Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

Xue-Jun Zhang, Zhi-Rong Yao and colleagues report a genome-wide association study for atopic dermatitis in the Chinese Han population. They identified two new susceptibility loci at 5q22 and 20q13.

Liang-Dan Sun
Feng-Li Xiao
Xue-Jun Zhang
Research12 Jun 2011
Nature Genetics

Volume: 43, P: 690-694
Efficient electrochemical production of glucaric acid and H₂ via glucose electrolysis

Renewable biomass conversion may afford high-value products from common materials, but catalysts usually require expensive metals and exhibit poor selectivities. Here, authors employ nickel-iron oxide and nitride electrocatalysts to produce H₂ and to convert glucose to glucaric acid selectively.

Wu-Jun Liu
Zhuoran Xu
Han-Qing Yu
ResearchOpen Access14 Jan 2020
Nature Communications

Volume: 11, P: 1-11
Acoustic extraordinary transmission manipulation based on proximity effects of heterojunctions

Zhi-Yong Tao
Ting Liu
Ya-Xian Fan
ResearchOpen Access31 Jan 2019
Scientific Reports

Volume: 9, P: 1-7
A non-invasive artificial intelligence model for identifying axillary pathological complete response to neoadjuvant chemotherapy in breast cancer: a secondary analysis to multicenter clinical trial

Teng Zhu
Yu-Hong Huang
Kun Wang
Research25 Jun 2024
British Journal of Cancer

Volume: 131, P: 692-701
Single-mode interface states in heterostructure waveguides with Bragg and non-Bragg gaps

Ya-Xian Fan
Tang-Qing Sang
Zhi-Yong Tao
ResearchOpen Access13 Mar 2017
Scientific Reports

Volume: 7, P: 1-7
Mettl1 knockdown alleviates cardiac I/R injury in mice by inactivating the Mettl1-CYLD-P53 positive feedback loop

Shu-ting Yu
Zhi-yong Sun
Wei-jie Du
Research16 Oct 2024
Acta Pharmacologica Sinica

Volume: 46, P: 592-605
PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3

Phytochrome photoreceptors mediate degradation of PIF transcription factors in the nucleus in response to light. Here Niet al. identify a family of nuclear protein kinases that interact with photoactivated phytochrome B and facilitate phytochrome-induced phosphorylation and degradation of PIF3.

Weimin Ni
Shou-Ling Xu
Peter H. Quail
ResearchOpen Access11 May 2017
Nature Communications

Volume: 8, P: 1-11
Addition of tanshinone IIA to UW solution decreases skeletal muscle ischemia-reperfusion injury

Hong-gang Wang
Zhi-yong Li
Xiao-lin Liu
Research01 Aug 2006
Acta Pharmacologica Sinica

Volume: 27, P: 991-999
IL-1β-activated mTORC2 promotes accumulation of IFN-γ⁺ γδ T cells by upregulating CXCR3 to restrict hepatic fibrosis

Qihui Liu
Quanli Yang
Ligong Lu
ResearchOpen Access01 Apr 2022
Cell Death & Disease

Volume: 13, P: 1-12
Discovery of Novel Inhibitors and Fluorescent Probe Targeting NAMPT

Xia Wang
Tian-Ying Xu
Chao-Yu Miao
ResearchOpen Access31 Jul 2015
Scientific Reports

Volume: 5, P: 1-16
Development of orthotopic mouse models for mid-low rectal cancer

Wen Chen
Kun Shi
Zhi-yong Qian
Research12 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1772-1781
A multitask deep learning model utilizing electrocardiograms for major cardiovascular adverse events prediction

Ching-Heng Lin
Zhi-Yong Liu
Ting-Yu Chang
ResearchOpen Access02 Jan 2025
npj Digital Medicine

Volume: 8, P: 1-10
Target margin design for real-time lung tumor tracking stereotactic body radiation therapy using CyberKnife Xsight Lung Tracking System

Zhi-Yong Yang
Yu Chang
Qin Li
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-11
The dynamic change of serum S100B levels from day 1 to day 3 is more associated with sepsis-associated encephalopathy

Long Wu
Qing Feng
Lina Zhang
ResearchOpen Access07 May 2020
Scientific Reports

Volume: 10, P: 1-10
Discovery of novel DprE1 inhibitors via computational bioactivity fingerprints and structure-based virtual screening

Xue-ping Hu
Liu Yang
Ting-jun Hou
Research19 Oct 2021
Acta Pharmacologica Sinica

Volume: 43, P: 1605-1615
CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice

Fu-wen Zuo
Zhi-yong Liu
Fan Yi
Research16 Jan 2024
Acta Pharmacologica Sinica

Volume: 45, P: 1019-1031
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression

Take home Figure. IL-17 promotes the development of heart failure. Upregulation of IL-17 activates NF-κB, which in turn suppresses the expression of CACNA1C encoding the pore-forming subunit of voltage gated Ltype calcium channel Cav1.2 and ATP2A2 encoding SERCA2a. Decreased expression of Cav1.2 and SERCA2a reduced cardiac contractility due to impaired calcium handling and promoted cardiac hypertrophic growth through the activation of calcium related signaling pathway, which eventually led to heart failure. PLN, phospholamban; SERCA2a, sarcoplasmic reticulum Ca²⁺-ATPase2a; RYR2, ryanodine receptor 2; CAMKII, calcium/calmodulin-dependent kinase II

Gen-long Xue
De-sheng Li
Zhen-wei Pan
Research15 Feb 2021
Acta Pharmacologica Sinica

Volume: 42, P: 1780-1789
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury

Zhi-yong Xie
Wei Dong
Xin-ling Liang
ResearchOpen Access22 Dec 2021
Acta Pharmacologica Sinica

Volume: 43, P: 2081-2093
HOTAIR contributes to the carcinogenesis of gastric cancer via modulating cellular and exosomal miRNAs level

Jie Zhang
Wei-qing Qiu
Zhi-yong Shen
ResearchOpen Access19 Sept 2020
Cell Death & Disease

Volume: 11, P: 1-15
New method for calculating the windward area of irregular fragments

Xing-yu Liu
Di-hua Ouyang
Chun-hai Yang
ResearchOpen Access24 Apr 2024
Scientific Reports

Volume: 14, P: 1-15
Biotransformation and bioaccessibility of active ingredients from Radix Astragali by Poria cocos during solid-state fermentation and in vitro digestion and antioxidant activity evaluation

Cai-Yun Chen
Run Zhang
Jia-Yu Zhang
ResearchOpen Access27 Apr 2023
Scientific Reports

Volume: 13, P: 1-13
Gamma-H2AX upregulation caused by Wip1 deficiency increases depression-related cellular senescence in hippocampus

Zhi-Yong He
Wen-Yue Wang
Ming Zhang
ResearchOpen Access30 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
Mesocortical BDNF signaling mediates antidepressive-like effects of lithium

Di Liu
Qian-Qian Tang
Jun-Li Cao
Research19 May 2020
Neuropsychopharmacology

Volume: 45, P: 1557-1566
Diverse kinase alterations and myeloid-associated mutations in adult histiocytosis

Jia Chen
Ai-lin Zhao
Jian Li
Research05 Oct 2021
Leukemia

Volume: 36, P: 573-576
Ovarian cancer treatment with a tumor-targeting and gene expression-controllable lipoplex

Zhi-Yao He
Feng Deng
Yu-Quan Wei
ResearchOpen Access30 Mar 2016
Scientific Reports

Volume: 6, P: 1-13
Involvement of the secreted protein Metrnl in human diseases

Zhu-wei Miao
Wen-jun Hu
Chao-yu Miao
Reviews30 Sept 2020
Acta Pharmacologica Sinica

Volume: 41, P: 1525-1530
Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

Chunhui Yuan
Zongyou Pan
Hongwei Ouyang
ResearchOpen Access12 Nov 2020
Bone Research

Volume: 8, P: 1-10
Remote preparation for single-photon two-qubit hybrid state with hyperentanglement via linear-optical elements

Xian-Fang Jiao
Ping Zhou
Zhi-Yong Wang
ResearchOpen Access20 Mar 2019
Scientific Reports

Volume: 9, P: 1-10
Metabolic profiles of prokaryotic and eukaryotic communities in deep-sea sponge Neamphius huxleyi indicated by metagenomics

Zhi-Yong Li
Yue-Zhu Wang
Hua-Jun Zheng
ResearchOpen Access27 Jan 2014
Scientific Reports

Volume: 4, P: 1-12
Effects of a commercially formulated glyphosate solutions at recommended concentrations on honeybee (Apis mellifera L.) behaviours

Qi-Hua Luo
Jing Gao
Qing-Yun Diao
ResearchOpen Access22 Jan 2021
Scientific Reports

Volume: 11, P: 1-8
Relationships of Non-coding RNA with diabetes and depression

Tian An
Jing Zhang
Guang-Jian Jiang
ResearchOpen Access24 Jul 2019
Scientific Reports

Volume: 9, P: 1-12
Vanadium dioxide-assisted broadband tunable terahertz metamaterial absorber

Huan Liu
Zhi-Hang Wang
Zhi-Yong Tao
ResearchOpen Access08 Apr 2019
Scientific Reports

Volume: 9, P: 1-10
Heterozygous IDH1^R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP

Shuang Wei
Jie Wang
Shuli Xia
Research30 May 2018
Oncogene

Volume: 37, P: 5160-5174
Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry

Isocitrate dehydrogenase (IDH) mutations can be identified by gas chromatography mass spectrometry (GC/MS). The sensitivity and specificity are 100% in gliomas for the accumulation of 2-hydroxyglutarate (2-HG), whereas the ratio of 2-HG/glutamic acid also serves as a reliable index. The modified mini-column GC/MS method could shorten the procedure to 40 min for rapid diagnosis.

Hao Xu
Yu-Kun Xia
Ying Mao
Research20 Dec 2018
Laboratory Investigation

Volume: 99, P: 588-598
The high concentration of progesterone is harmful for endometrial receptivity and decidualization

Yu-Xiang Liang
Li Liu
Zeng-Ming Yang
ResearchOpen Access15 Jan 2018
Scientific Reports

Volume: 8, P: 1-12
Tobacco vein banding mosaic virus 6K2 Protein Hijacks NbPsbO1 for Virus Replication

Chao Geng
Zhi-Yong Yan
Xiang-Dong Li
ResearchOpen Access23 Feb 2017
Scientific Reports

Volume: 7, P: 1-16

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