The intestinal barrier has an important role in organismal homeostasis; however, the mechanisms that mediate intestinal epithelial aging are incompletely understood. Here, Zhang et al. show that RAB-10 functionality is impaired in aging worms, affecting endocytic recycling and, thus, contributing to the age-related deterioration of adherens junctions.
- Jing Zhang
- Zongyan Jiang
- Anbing Shi
