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Spine regulation is the biological process by which the structure or function of a dendritic spine is modulated by factors such as neuronal excitation. The structure of dendritic spines is highly variable; however, a typical spine consists of a spine head that may be mushroom- or cup-shaped and a thinner neck region.
Morphological and electrophysiological understanding of cerebrospinal fluid-contacting neurons (CSF-cNs) is extended by analysis in the mouse, revealing that they express PKD2L1 and ASICs along with ligand- and voltage-gated channels modulated by metabotropic receptors.
Individual boutons on mouse corticostriatal axons exhibit differential selectivity for rewarded and unrewarded movements during motor learning, and the proportion of reward-responsive boutons increases.
Here, the authors used functional ultrasound imaging to map human spinal cord activity during urodynamically controlled micturition, showing that blood flow closely tracks bladder pressure and offering new insights into spinal cord regulation of micturition.
A series of papers provide an overview of the adult Drosophila melanogaster whole-brain connectome and how the resulting resource allows for more sophisticated approaches to investigate computations in the fly brain.
The binding of psychedelics to the BDNF receptor TrkB boosts plasticity in cultured neurons and underlies the antidepressant-like effects of these compounds in mice.
