Little is known about the function of most long non-coding RNAs. But a suite of new tools might change that.
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References
Au, K. F. et al. Proc. Natl Acad. Sci. USA 110, E4821–E4830 (2013).
Durruthy-Durruthy, J. et al. Nature Genet. 48, 44–52 (2016).
Hangauer, M. J., Vaughn, I. W. & McManus, M. T. PLoS Genet. 9, e1003569 (2013).
Cabili, M. N. et al. Genome Biol. 16, 20 (2015).
Jinek, M. et al. Science 343, 1247997 (2014).
Chu, C. et al. Cell 161, 404–416 (2015).
McHugh, C. A. et al. Nature 521, 232–236 (2015).
Minajigi, A. et al. Science 349, aab2276 (2015).
Novikova, I. V., Hennelly, S. P. & Sanbonmatsu, K. Y. Nucleic Acids Res. 40, 5034–5051 (2012).
Spitale, R. C. et al. Nature Chem. Biol. 9, 18–20 (2013).
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Chi, K. Finding function in mystery transcripts. Nature 529, 423–425 (2016). https://doi.org/10.1038/529423a
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DOI: https://doi.org/10.1038/529423a
