Sir,

Haematopoietic stem cell transplantation (HSCT) including peripheral blood stem cell transplantation (PBSCT) and bone marrow transplantation (BMT) is now well recognized as the curative treatment modality for severe aplastic anaemia and haematological malignancy. However, HSCT is associated with several complications. These result from the side effects of the treatment regimen such as high-dose chemotherapy, steroid treatment, and irradiation that induced pancytopenia after transplantation, and that of the immune reaction like graft-versus-host disease (GVHD).1 The ocular complications of the anterior segment after BMT are common while those of the posterior segment are not frequently reported. The most commonly reported posterior segment complications are either intraretinal or vitreous haemorrhages according to the literatures.2 We present two cases of exudative bullous retinal detachment (RD) in two patients after PBSCT who develop severe and potentially vision-threatening complications. Since our two cases died shortly after the diagnosis, bullous RD may be a poor prognostic factor for survival after PBSCT.

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