Figure 5
From: The circadian mutation PER2S662G is linked to cell cycle progression and tumorigenesis
PER2S662 mutations increased tumor incidence in the p53R172H/+ background. (a) Overall survival. (b) Male survival. Survival curves (Kaplan–Meier representation) of the indicated mouse cohorts. n=number of mice per genotype. The survival curves are plotted with respect to the number of weeks using SPSS software. Statistical significance was assessed using the log-rank test and is indicated (P-value). Alterations in median life span of the indicated genotypes relative to control (increase as plus or decrease as minus) are labeled
