Tracking humans and microbes

Lloréns-Rico, Verónica; Raes, Jeroen

doi:10.1038/d41586-019-01591-y

NEWS AND VIEWS
29 May 2019

Tracking humans and microbes

The Human Microbiome Project put the health-associated microbes found in humans on centre stage. The project’s second phase shows how microbial disturbance in disease is linked to host processes.

By

Verónica Lloréns-Rico⁰ &
Jeroen Raes¹

Verónica Lloréns-Rico
1. Verónica Lloréns-Rico is at the Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium, and at the VIB Center for Microbiology, Leuven.
View author publications

Search author on: PubMed Google Scholar
Jeroen Raes
1. Jeroen Raes is at the Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium, and at the VIB Center for Microbiology, Leuven.
View author publications

Search author on: PubMed Google Scholar

Access through your institution

Buy or subscribe

Precision medicine can be defined as “an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person” (see go.nature.com/2wv1ch9). Now, studies from the US National Institutes of Health Integrative Human Microbiome Project (iHMP) provide a resource of microbial and human data tracking the progression of two diseases and pregnancy that will help efforts to understand host-associated microorganisms and their interactions with their human host. The resource will be of great value for aiding the precision-medicine approaches of the future. This work includes three flagship studies: two research papers in Nature, one by Zhou et al.¹ and another by Lloyd-Price et al.² and a paper in Nature Medicine by Fettweis et al.³. There is also a Perspective in Nature by the iHMP Research Network Consortium⁴, and another research paper in Nature Medicine by Serrano et al.⁵.

Access options

Access through your institution

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Nature 569, 632-633 (2019)

doi: https://doi.org/10.1038/d41586-019-01591-y

References

Zhou, W. et al. Nature 569, 663–671 (2019).
Article Google Scholar
Lloyd-Price, J. et al. Nature 569, 655–662 (2019).
Article Google Scholar
Fettweis, J. M. et al. Nature Med. https://doi.org/10.1038/s41591-019-0450-2 (2019).
Article Google Scholar
The Integrative HMP (iHMP) Research Network Consortium. Nature 569, 641–648 (2019).
Article Google Scholar
Serrano, M. G. et al. Nature Med. https://doi.org/10.1038/s41591-019-0465-8 (2019).
Article Google Scholar
Qin, J. et al. Nature 464, 59–65 (2010).
Article PubMed Google Scholar
The Human Microbiome Project Consortium. Nature 486, 207–214 (2012).
Article PubMed Google Scholar
Turnbaugh, P. J. et al. Nature 457, 480–484 (2009).
Article PubMed Google Scholar
Eckburg, P. B. et al. Science 308, 1635–1638 (2005).
Article PubMed Google Scholar
Costello, E. K. et al. Science 326, 1694–1697 (2009).
Article PubMed Google Scholar
Vandeputte, D., Tito, R. Y., Vanleeuwen, R., Falony, G. & Raes, J. FEMS Microbiol. Rev. 41, S154–S167 (2017).
PubMed Google Scholar
Gloor, G. B., Macklaim, J. M., Pawlowsky-Glahn, V. & Egozcue, J. J. Front. Microbiol. 8, 2224 (2017).
Article PubMed Google Scholar
Falony, G. et al. Science 352, 560–564 (2016).
Article PubMed Google Scholar
Vandeputte, D. et al. Nature 551, 507–511 (2017).
Article PubMed Google Scholar
He, Y. et al. Nature Med. 24, 1532–1535 (2018).
Article PubMed Google Scholar
Chen, R. et al. Cell 148, 1293–1307 (2012).
Article PubMed Google Scholar
Price, N. D. et al. Nature Biotechnol. 35, 747–756 (2017).
Article PubMed Google Scholar

Download references

Reprints and permissions

Subjects

Jobs

Recruitment Announcement for High-Level Talents at DIMST, CAS

I) Leaders for twelve research divisions II) Academic Leading Talents III) Outstanding Young Talents

No. 333 Pingdong Road, Songshan Lake Science City, Dongguan, Guangdong

Dongguan Institute of Materials Science and Technology, Chinese Academy of Sciences (DIMST, CAS)
Faculty Positions Available at Shenzhen University of Advanced Technology

Join us!

Shenzhen, Guangdong, China

Shenzhen University of Advanced Technology
Institute Positions Available at Shenzhen University of Advanced Technology

Join us!

Shenzhen, Guangdong, China

Shenzhen University of Advanced Technology
Global Recruitment for Faculty, Postdocs, and Specialists at Hangzhou Institute of Medicine, CAS

Seeking exceptional Senior/Junior PIs, Postdocs, and Core Specialists globally year-round

Hangzhou, China

Hangzhou Institute of Medicine Chinese Academy of Sciences (HIMCAS)
Teaching & Research Positions (Life Sciences, Environment, Medicine, Computing)

Jointly sponsored by the Hangzhou Municipal People's Government and the University of Chinese Academy of Sciences.

Hangzhou, Zhejiang, China

Hangzhou Institute of Advanced Study, UCAS

[1] Zhou, W. et al. Nature 569, 663–671 (2019).
Article Google Scholar

[2] Lloyd-Price, J. et al. Nature 569, 655–662 (2019).
Article Google Scholar

[3] Fettweis, J. M. et al. Nature Med. https://doi.org/10.1038/s41591-019-0450-2 (2019).
Article Google Scholar

[4] The Integrative HMP (iHMP) Research Network Consortium. Nature 569, 641–648 (2019).
Article Google Scholar

[5] Serrano, M. G. et al. Nature Med. https://doi.org/10.1038/s41591-019-0465-8 (2019).
Article Google Scholar

[6] Qin, J. et al. Nature 464, 59–65 (2010).
Article PubMed Google Scholar

[7] The Human Microbiome Project Consortium. Nature 486, 207–214 (2012).
Article PubMed Google Scholar

[8] Turnbaugh, P. J. et al. Nature 457, 480–484 (2009).
Article PubMed Google Scholar

[9] Eckburg, P. B. et al. Science 308, 1635–1638 (2005).
Article PubMed Google Scholar

[10] Costello, E. K. et al. Science 326, 1694–1697 (2009).
Article PubMed Google Scholar

[11] Vandeputte, D., Tito, R. Y., Vanleeuwen, R., Falony, G. & Raes, J. FEMS Microbiol. Rev. 41, S154–S167 (2017).
PubMed Google Scholar

[12] Gloor, G. B., Macklaim, J. M., Pawlowsky-Glahn, V. & Egozcue, J. J. Front. Microbiol. 8, 2224 (2017).
Article PubMed Google Scholar

[13] Falony, G. et al. Science 352, 560–564 (2016).
Article PubMed Google Scholar

[14] Vandeputte, D. et al. Nature 551, 507–511 (2017).
Article PubMed Google Scholar

[15] He, Y. et al. Nature Med. 24, 1532–1535 (2018).
Article PubMed Google Scholar

[16] Chen, R. et al. Cell 148, 1293–1307 (2012).
Article PubMed Google Scholar

[17] Price, N. D. et al. Nature Biotechnol. 35, 747–756 (2017).
Article PubMed Google Scholar

Access options

References

Related Articles

Subjects

Latest on:

Jobs

Recruitment Announcement for High-Level Talents at DIMST, CAS

Faculty Positions Available at Shenzhen University of Advanced Technology

Institute Positions Available at Shenzhen University of Advanced Technology

Global Recruitment for Faculty, Postdocs, and Specialists at Hangzhou Institute of Medicine, CAS

Teaching & Research Positions (Life Sciences, Environment, Medicine, Computing)

Search

Quick links