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Showing 1–4 of 4 results
Advanced filters: Author: Verónica Lloréns-Rico Clear advanced filters

  • The Human Microbiome Project put the health-associated microbes found in humans on centre stage. The project’s second phase shows how microbial disturbance in disease is linked to host processes.

    • Verónica Lloréns-Rico
    • Jeroen Raes
    News & Views
    Nature
    Volume: 569, P: 632-633

  • Here, the authors use simulated quantitative gut microbial communities to benchmark the performance of 13 common data transformations in determining diversity as well as microbe-microbe and microbe-metadata associations, finding that quantitative approaches incorporating microbial load variation outperform computational strategies in downstream analyses, urging for a widespread adoption of quantitative approaches, or recommending specific computational transformations whenever determination of microbial load of samples is not feasible.

    • Verónica Lloréns-Rico
    • Sara Vieira-Silva
    • Jeroen Raes
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Here, the authors profile the respiratory microbiome of COVID-19 patients and link clinical practices, such as mechanical ventilation, with vast changes in the microbiota. In the lungs, oral bacteria are found physically associated with proinflammatory immune cells, thus possibly contributing to exacerbated immune responses in severe disease

    • Verónica Lloréns-Rico
    • Ann C. Gregory
    • Jeroen Raes
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12