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Fastest-ever calcium sensors broaden the potential of neuronal imaging

Proteins have been developed that emit flashes of light in response to influxes of calcium ions into cells on millisecond timescales. Two sets of scientists discuss the legacy and future of these proteins.
By
  1. Michael B. Ryan

    1. Michael B. Ryan is in the Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.

  2. Anne K. Churchland

    1. Anne K. Churchland is in the Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.

  3. Yiyang Gong

    1. Yiyang Gong is in the Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA, and in the Department of Neurobiology, Duke University.

  4. Casey Baker

    1. Casey Baker is in the Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA.

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Nature 615, 804-805 (2023)

doi: https://doi.org/10.1038/d41586-023-00704-y

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Competing Interests

The authors declare no competing interests.

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