Summary
The optimum family structure of two experimental designs ((i) Non segregating generations plus F2's and backcrosses; (ii) The North Carolina Expt. III) have been investigated with respect to the estimation of additive (D) and non additive (H) genetic variation for a quantitative trait. In the former design it is shown that the generations should ideally be replicated in proportion to the total variation of each generation (if this is known) while in the latter, one should aim to sample at least 20 F2 plants. The relative efficiencies of the two designs are compared and the considerable advantages of the N.C. Expt. III design are illustrated and emphasised.
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Kearsey, M. The efficiency of the North Carolina expt. III and the selfing, backcrossing series for estimating additive and dominance variation. Heredity 45, 73–82 (1980). https://doi.org/10.1038/hdy.1980.51
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DOI: https://doi.org/10.1038/hdy.1980.51
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