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New onset diabetes: can it be delayed?

Journal of Human Hypertension volume 22, pages 517–519 (2008)Cite this article

The prevalence of type 2 diabetes is increasing internationally at astounding rates. It is estimated that the number of adults living with diabetes in the world will double from 150 million in 1995 to 300 million people by the year 2025. India, China and the United States have been identified as countries with the highest level of diabetes.1 With the alarming worldwide growing rates of diabetes and the associated cardiovascular complications, numerous efforts have been made to identify potential predictors of developing type 2 diabetes.

A combined analysis of six prospective studies investigating predictors of progression from impaired glucose tolerance to type 2 diabetes demonstrated that fasting glucose and post-challenge glucose concentrations as well as body mass index (BMI) at the time of diagnosis were the strongest predictors correlated with progression from impaired glucose tolerance to type 2 diabetes.2 However, with respect to BMI the analysis further demonstrated that in the cohorts with the highest rates of diabetes, BMI was not found to be associated with the development of type 2 diabetes when adjusted for the baseline glucose levels. Moreover, the authors also discovered that gender and family history were not strongly correlated with progression to type 2 diabetes development. In addition, this analysis indicated an inconsistent relationship between age and progression to type 2 diabetes.

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Authors and Affiliations

  1. The Hypertensive Diseases Unit, Section of Endocrinology, Diabetes and Metabolism, University of Chicago Pritzker School of Medicine, Chicago, IL, USA

    K P Vasisht & G Bakris

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  1. K P Vasisht
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  2. G Bakris
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Correspondence to G Bakris.

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Vasisht, K., Bakris, G. New onset diabetes: can it be delayed?. J Hum Hypertens 22, 517–519 (2008). https://doi.org/10.1038/jhh.2008.48

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