Figure 1

mRNA expression of AMH, AMHRII, ALK2, ALK3, ALK6, Smad1, and Smad5 in GCTs. Thirty GCTs (recurrent GCTs nos 21, 24–26) were analyzed by PCR for the expressions of AMHRII, ALK2, ALK3, ALK6, Smad1, and Smad5 mRNAs (a). AMH and AMHRII mRNA expressions were quantified relative to actin by quantitative PCR in 28 (22 primary and 6 recurrent) GCTs (b, c). AMH mRNA expression correlated positively to AMHRII mRNA expression (b) and negatively to tumor size (c) (P=0.0391).