Figure 6 | Laboratory Investigation

Figure 6

From: Norcantharidin inhibits the expression of extracellular matrix and TGF-β1 in HK-2 cells induced by high glucose independent of calcineurin signal pathway

Figure 6

Effects of NCTD on NFATc nuclear translocation and protein expression in HK-2 cells stimulated by high glucose. (a) Immunofluorescence staining indicated that NCTD inhibited the nuclear translocation of NFATc from cytoplasm to the nucleus ( × 800). The blue-colored stain is nuclear counterstained with Hoechest 33258. (b) Western blot showed that NCTD decreased the upregulation of NFATc nuclear deposition. C, 5.5 mM D-glucose; HG, 30 mM D-glucose; HG+NCTD, 30 mM D-glucose plus 5 mg/l NCTD.

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