Extended Data Figure 6: qPCR analysis of individual var genes in various parasite clones.
From: Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria
a, Transcription profile of 3D7-G7, PfRNase II–FKBP-H3, G1, C3 clones and two subclones of C3 (scB7 and scB1). The predominantly transcribed var genes with distinct ups type are indicated on each column. Expression levels are normalized to expression of the seryl-tRNA synthetase gene. b, Control parasite clones only predominantly transcribe a single var gene. The five subtype var genes and four control genes are shown on the top of the graph. Data are shown as relative copy numbers related to the seryl-tRNA synthetase gene. Samples were harvested at the ring stage.
