Extended Data Figure 2: Anti-Cryptosporidium activity does not correlate with mammalian cell toxicity.
From: A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis
Correlation of C. parvum cytopathic effect versus HepG2 cytotoxicity assay for selected pyrazolopyridine and imidazopyrazine analogues along with BQR695 and MMV390048. Data shown here are geometric mean EC50 values, with at least two biological replicates.
