Extended Data Figure 3: Recombinant C. parvum cgd8_4500 shows phosphatidylinositide kinase activity.
From: A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis
C. parvum cgd8_4500 was expressed in insect cells using a Baculovirus system and recombinant enzyme was purified. A Michaelis–Menten plot of phosphatidylinositide kinase reaction with 3 nM CpPI(4)K enzyme at varying ATP concentrations is shown. Data shown here are a representative graph of two independent biological replicates.
