Supplementary Figure 5: ATM-dependent p14ARF regulation affects ribosomal biogenesis. | Nature Cell Biology

Supplementary Figure 5: ATM-dependent p14ARF regulation affects ribosomal biogenesis.

From: Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer

Supplementary Figure 5

a. Schematic presentation of the findings described in panels b and c. b. IBs depicting the localization over time of NPM/B23 and p14ARF in ATM compromised H1299 cells in total lysates, nucleoplasmic and nucleolar fractions. c. Modulation of p14ARF levels by ATMi affects TTF-I nucleoplasmic/nucleolar localization. IBs depicting the status of TTF-I and p14ARF in H1299 total cell lysates, nucleoplasmic and nucleolar fractions, respectively upon DMSO, ATMi and ATMi/siARF treatments.

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