Supplementary Figure 3
(a) Nascent chromatin enrichment of factors proposed to deal with DNA–RNA duplexes and protein degradation at the fork20,56. (b) Nascent chromatin enrichment of origin recognition and licensing factors. (c) Coverage of the PCNA interactome by NCC-SILAC. Bars illustrate factors identified in NCC relative to those reported in the literature, numbers are indicated in brackets. Functional groups of PCNA interactors are according to Moldovan et al., 2007. For details see Supplementary Table 2. (d) Analysis of factors enriched on nascent chromatin by western blot. For comparison the log2 nascent chromatin enrichment is indicated. (e) Nascent chromatin enrichment of lysine and arginine methyltransferases (violet) and demethylases (grey). (f) Nascent chromatin enrichment of RNA polymerases. Only unique subunits are shown. All Nascent chromatin enrichments are presented as in Fig. 1h.
