Supplementary Figure 3: Knockdown of HOXA5 or HOXA7 does not lead to changes in BRDU incorporation in FL immunophenotypic HSPCs. | Nature Cell Biology

Supplementary Figure 3: Knockdown of HOXA5 or HOXA7 does not lead to changes in BRDU incorporation in FL immunophenotypic HSPCs.

From: Medial HOXA genes demarcate haematopoietic stem cell fate during human development

Supplementary Figure 3: Knockdown of HOXA5 or HOXA7 does not lead to changes in BRDU incorporation in FL immunophenotypic HSPCs.

(A) Representative FACS plots and quantification of cell cycle analyses based on BrdU incorporation (mean from one experiment with 2 independent donors, statistics source data can be found in Supplementary Table 7) of control vector and HOXA5 and HOXA7 shRNA vector transduced FL-HSPCs. (B,C) Examples of cell cycle activators (B) and inhibitors (C) from RNA-seq analyses of FL immunophenotypic HSPCs with HOXA7 knockdown compared to empty vector controls (showing mean from 4 independent experiments, values used to generate graphs can be found in Supplementary Table 4 and GEO database GSE76685).

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