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Imaging gene expression: tiny signals make a big noise

Nature Chemical Biology volume 2, pages 181–182 (2006)Cite this article

The hypothesis of ubiquitous fluctuations in gene expression has spurred the development of general methods for tracking temporal changes in protein concentrations in individual cells. The determination of protein levels with single-molecule sensitivity represents a significant advancement in the monitoring of cellular behavior that is driven by gene expression.

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Figure 1: Two novel techniques for monitoring gene expression with single-protein-molecule sensitivity.

Jessica Iannuzzi

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Authors and Affiliations

  1. Department of Bioengineering,

    Diane Longo & Jeff Hasty

  2. Department of Bioengineering and the Institute for Nonlinear Science, University of California San Diego, La Jolla, 92093, California, USA

    Diane Longo & Jeff Hasty

Authors
  1. Diane Longo
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  2. Jeff Hasty
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Longo, D., Hasty, J. Imaging gene expression: tiny signals make a big noise. Nat Chem Biol 2, 181–182 (2006). https://doi.org/10.1038/nchembio0406-181

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