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Redox metabolites such as reactive oxygen species and reactive sulfur species are produced as a byproduct of aerobic metabolism and can be either beneficial or detrimental depending on cellular context. This Focus issue features a collection of articles exploring emerging research areas in redox biology.
We asked a collection of redox biologists, “What do you think are the most exciting frontiers or the most needed developments in redox biology?” — here is what they said.
This Comment discusses how an integrative cross-disciplinary research program in China aims to link RNA biology with translational drug discovery to accelerate RNA innovation and contribute to a global shift toward rational, RNA-centered therapeutics.
Machine learning-based tools have revolutionized how scientists study protein structure. Here, Nature Chemical Biology speaks to Cecilia Clementi, Bruno Correia and Peilong Lu about progress in developing computational tools for predicting protein structure and properties, how these programs can be used for protein design, and the developments they would like to see in the field.