Table 2 Location and phenotype of mouse tumours isolated from mice of the indicated genetic backgrounds.
Mouse | NPM–ALK | NPM–ALK/RAG2−/− | NPM–ALK/OTI | |||
|---|---|---|---|---|---|---|
Location | Phenotype | Location | Phenotype | Location | Phenotype | |
1 | Thymus | 4,8,44,25,117,30 (DP) | Thymus | 4,8,44 (DP) | LN (c,a,i,m), Spleen | 4,44,25,117 (SP) |
2 | Thymus | 4,8,44,25,117 (DP) | Thymus | 4,44,25,117 (SP) | Thymus | 4,44,117 (SP) |
3 | Thymus | 4,8,117 (DP) | Thymus | 4,8,44,25 (DP) | LN (c,a,i,m), Spleen | Null,25 |
4 | Thymus | 4,8,44,25,117,30 (DP) | Thymus | 4,8,44,25 (DP) | LN (m), Spleen | Null,44 |
5 | Thymus | 4,44,117,30 (SP) | Thymus | 4,8,44 (DP) | LN (i,m), Spleen | Null,44,25,117 |
6 | Thymus | 44,25,117 (DN) | Thymus | 4,44,25 (SP) | LN (c,i,md) | Null,44,25 |
7 | LN (c,a,i,m), Spleen | Null | Thymus | 4,8,25,30 (DP) | LN (c,i,m,md), Spleen | Null,44,25 |
8 | Thymus | 4,44,117 (SP) | Thymus | 4,8,44,25,30 (DP) | LN (m), Spleen | 4,44,Vα2 (SP) |
9 | Thymus | 4,8,44,117 (DP) | Thymus | 4,8,25 (DP) | LN (c,a,i,m) | Null,25 |
10 | Thymus | 4,44,25,117,30 (SP) | Thymus | 4,8,44,25 (DP) | LN (c,a,i,m) | 8,25,117 SP |
