Figure 2: Deficiency in haematopoietic ESL-1 generates a quiescent bone marrow environment. | Nature Communications

Figure 2: Deficiency in haematopoietic ESL-1 generates a quiescent bone marrow environment.

From: Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability

Figure 2

(a) Experimental scheme for the generation of mixed chimeric mice by bone marrow transplantation. (b) Representative plots of BrdU incorporation in LSK and myeloid progenitors (MPs) in WT:WT-DsRed or Glg1−/−:WT DsRed chimeric mice. (c) Percentage of BrdU-incorporating WT-DsRed and Glg1−/− cells in the mixed chimeric mice shown in b; n=6. NS, not significant. Each circle represents a mouse. Bar graphs show mean±s.e.m.

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