Figure 4: Molecular modelling based on small-angle X-ray scattering.

Ab initio bead models of IscS (a), the solution (b) and X-ray (c) structures of IscU, CyaY (d), IscU/IscS (e), CyaY/IscS (f) and CyaY/IscS/IscU (g) complexes. The models were obtained from DAMMIF (grey semitransparent spheres) superimposed with rigid body models by the software SASREF. The two components of the crystallographic dimer model of IscS are displayed as cyan and blue Cα traces. For each model, the right views are rotated counterclockwise around the vertical y axis.