Figure 1: Detection of chromosomal duplications using RNA-Seq data.
From: Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
(a) e-Karyotyping analysis of samples from RNA-Seq studies. Shown are moving average plots of representative examples of chromosomal aneuploidies in pluripotent and pluripotent-derived cells. The grey background represents statistically significant aneuploidy as recognized by the piecewise constant fit algorithm. (b) eSNP-Karyotyping of the aberrant samples shown in a. Colour bars represent the FDR-corrected P value. Positions with a P value lower than 0.01 are marked by a black line. (c) Two representative samples from the e-Karyotyping analysis for PSC-derived pancreatic progenitor cells. (d) eSNP-Karyotyping for the red sample analysed in c.
