Table 2 GREAT functional enrichment analysis of genomic regions for high 5 hmC CpGs (n=3,876).
GO: biological process | Hyper fold enrichment | Hyper FDR Q value |
|---|---|---|
Negative regulation of receptor catabolic process | 12.37 | 1.81E−08 |
Regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter | 4.94 | 1.66E−10 |
Positive regulation of cardiac muscle hypertrophy | 4.73 | 1.84E−08 |
Cytokine production involved in immune response | 4.72 | 9.42E−09 |
Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 4.05 | 3.25E−10 |
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 3.93 | 4.65E−09 |
Viral genome replication | 3.82 | 2.85E−08 |
Positive regulation of mRNA catabolic process | 3.72 | 3.21E−09 |
Regulation of histone deacetylation | 3.45 | 3.11E−10 |
Regulation of protein deacetylation | 3.17 | 6.43E−10 |
Production of molecular mediator of immune response | 3.14 | 6.15E−12 |
Regulation of mRNA stability | 3.13 | 2.51E−11 |
Regulation of RNA stability | 3.1 | 1.65E−12 |
Peptidyl-threonine modification | 2.92 | 1.71E−08 |
Somatic stem cell maintenance | 2.25 | 4.14E−09 |
Regulation of fat cell differentiation | 2.24 | 7.68E−11 |
Protein import into nucleus | 2.11 | 2.68E−09 |
Notch signalling pathway | 2.09 | 9.38E−13 |
Nuclear import | 2.08 | 4.12E−09 |
Positive regulation of response to external stimulus | 2.05 | 1.72E−11 |
