Figure 4: Patient’s fibroblasts show reduced induction of gene expression after IFN-α and IFN-γ stimulation.
From: Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection
Cells were stimulated with IFN-α for 15 h (a) or IFN-γ for 8 h (b). qPCR was done in triplicate. mRNA fold change is shown relative to the untreated control fibroblasts. *P<0.05, **P<0.005, ***P<0.0005. Graphs show mean values±s.d.
