Figure 1: Expression and pathological significance of MICU1 in OvCa.
From: MICU1 drives glycolysis and chemoresistance in ovarian cancer
(a) Expression of MICU1 in various ovarian cell lines as determined by immunoblotting. Actin is used as the loading control. (b) Kaplan-Meier overall survival curves in MICU1 low and high expression OvCa cases from GEO databases. The proportion survival is plotted versus time since diagnosis in months. Kaplan-Meier curves with a log-rank test where P value<0.05 considered significant. (c) Immunohistochemical (IHC) staining of a tissue microarray of drug-resistant epithelial OvCa samples for MICU1 (1:150). Representative images taken at × 4 magnification are shown of (i) weak, (ii) moderate and (iii) high staining. Inset shows magnified areas of individual IHC stains taken at × 20 magnification. Scale: 100 μm.
